{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:12:50Z","timestamp":1791227570029,"version":"4.1.0"},"reference-count":81,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,3,19]],"date-time":"2023-03-19T00:00:00Z","timestamp":1679184000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Abnormalities in cellular differentiation during embryo-fetal period may lead to various malformations of the spine. Caudal regression syndrome (CRS) is a group of defects with premature growth\/development termination of the vertebral column. CRS can be divided into three types: sirenomelia, complete absence of the sacrum and partial absence of the sacrum. Genitourinary and gastrointestinal anomalies are common, with neurogenic bladder and bowel incontinence. Treatment of patients with CRS is complex and multidisciplinary and should be comprehensive. The most common orthopedic problems are: spinal deformity (kyphosis and scoliosis), spinopelvic instability and lower limbs deformities.<\/jats:p>","DOI":"10.3390\/children10030589","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T04:33:31Z","timestamp":1679286811000},"page":"589","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Caudal Regression Syndrome\u2014A Narrative Review: An Orthopedic Point of View"],"prefix":"10.3390","volume":"10","author":[{"given":"Barbara","family":"Jasiewicz","sequence":"first","affiliation":[{"name":"Department of Orthopedics and Rehabilitation, Jagiellonian University Collegium Medicum, Balzera 15, 34-500 Zakopane, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Kacki","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Rehabilitation, Jagiellonian University Collegium Medicum, Balzera 15, 34-500 Zakopane, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/10790268.2017.1369211","article-title":"Atypical caudal regression syndrome with agenesis of lumbar spine and presence of sacrum\u2013case report and literature review","volume":"41","author":"Szumera","year":"2017","journal-title":"J. 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