{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:02:29Z","timestamp":1760148149604,"version":"build-2065373602"},"reference-count":38,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T00:00:00Z","timestamp":1680480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>The diagnosis of Kawasaki disease (KD) is challenging and often delayed mainly in case of young infants and in presence of an incomplete disease and atypical features. Facial nerve palsy is one of the rare neurologic symptoms of KD, associated with a higher incidence of coronary arteries lesions and may be an indicator of a more severe disease. Here, we describe a case of lower motor neuron facial nerve palsy complicating KD and perform an extensive literature review to better characterize clinical features and treatment of patients with KD-associated facial nerve palsy. The patient was diagnosed at the sixth day of disease and presented extensive coronary artery lesions. A prompt treatment with intravenous immunoglobulins, aspirin and steroids obtained a good clinical and laboratory response, with resolution of facial nerve palsy and improvement of coronary lesions. The incidence of facial nerve palsy is 0.9\u20131.3%; it is often unilateral, transient, more frequent on the left and seemingly associated with coronary impairment. Our literature review showed coronary artery involvement in the majority of reported cases (27\/35, 77%) of KD with facial nerve palsy. Unexplained facial nerve palsy in young children with a prolonged febrile illness should prompt consideration of echocardiography to exclude KD and start the appropriate treatment.<\/jats:p>","DOI":"10.3390\/children10040679","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T04:45:33Z","timestamp":1680497133000},"page":"679","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Incomplete Kawasaki Disease with Peripheral Facial Nerve Palsy and Lung Nodules: A Case Report and Literature Review"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8181-2219","authenticated-orcid":false,"given":"Marco","family":"Maglione","sequence":"first","affiliation":[{"name":"Pediatric Emergency Unit, Santobono-Pausilipon Children\u2019s Hospital, 80129 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annalisa","family":"Barlab\u00e0","sequence":"additional","affiliation":[{"name":"Department of Woman, Child and of General and Specialized Surgery, Universit\u00e0 degli Studi della Campania L. Vanvitelli, 81100 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"Grieco","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Santobono-Pausilipon Children\u2019s Hospital, 80129 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosaria","family":"Cosimi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Santobono-Pausilipon Children\u2019s Hospital, 80129 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giangiacomo","family":"Di Nardo","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Santobono-Pausilipon Children\u2019s Hospital, 80129 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni Maria","family":"Di Marco","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Santobono-Pausilipon Children\u2019s Hospital, 80129 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1500-0746","authenticated-orcid":false,"given":"Monica","family":"Gelzo","sequence":"additional","affiliation":[{"name":"CEINGE-Biotecnologie Avanzate, Scarl, 80131 Naples, Italy"},{"name":"Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universit\u00e0 di Napoli Federico II, 80138 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Castaldo","sequence":"additional","affiliation":[{"name":"CEINGE-Biotecnologie Avanzate, Scarl, 80131 Naples, Italy"},{"name":"Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universit\u00e0 di Napoli Federico II, 80138 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celeste","family":"Tucci","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Pediatric Neurology, Santobono-Pausilipon Children\u2019s Hospital, 80129 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaella Margherita","family":"Iodice","sequence":"additional","affiliation":[{"name":"Pediatric Emergency Unit, Santobono-Pausilipon Children\u2019s Hospital, 80129 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Concetta","family":"Lonardo","sequence":"additional","affiliation":[{"name":"Pediatric Emergency Unit, Santobono-Pausilipon Children\u2019s Hospital, 80129 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8159-2359","authenticated-orcid":false,"given":"Vincenzo","family":"Tipo","sequence":"additional","affiliation":[{"name":"Pediatric Emergency Unit, Santobono-Pausilipon Children\u2019s Hospital, 80129 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8073-7114","authenticated-orcid":false,"given":"Antonietta","family":"Giannattasio","sequence":"additional","affiliation":[{"name":"Pediatric Emergency Unit, Santobono-Pausilipon Children\u2019s Hospital, 80129 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/s13052-018-0536-3","article-title":"Kawasaki disease: Guidelines of the Italian Society of Pediatrics, part I\u2014Definition, epidemiology, etiopathogenesis, clinical expression and management of the acute phase","volume":"44","author":"Marchesi","year":"2018","journal-title":"Ital. 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