{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:06:22Z","timestamp":1791929182905,"version":"4.3.4"},"reference-count":144,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T00:00:00Z","timestamp":1684713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>As the leading cause of neonatal morbidity and mortality, preterm birth is recognized as a major public health concern around the world. The purpose of this review is to analyze the connection between infections and premature birth. Spontaneous preterm birth is commonly associated with intrauterine infection\/inflammation. The overproduction of prostaglandins caused by the inflammation associated with an infection could lead to uterine contractions, contributing to preterm delivery. Many pathogens, particularly Chlamydia trachomatis, Neisseria\u00a0gonorrhoeae, Trichomonas\u00a0vaginalis, Gardnerella\u00a0vaginalis, Ureaplasma\u00a0urealyticum, Mycoplasma\u00a0hominis, Actinomyces, Candida spp., and Streptococcus spp. have been related with premature delivery, chorioamnionitis, and sepsis of the neonate. Further research regarding the prevention of preterm delivery is required in order to develop effective preventive methods with the aim of reducing neonatal morbidity.<\/jats:p>","DOI":"10.3390\/children10050907","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T05:04:44Z","timestamp":1684731884000},"page":"907","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":87,"title":["Maternal Infection and Preterm Birth: From Molecular Basis to Clinical Implications"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7108-211X","authenticated-orcid":false,"given":"George","family":"Daskalakis","sequence":"first","affiliation":[{"name":"First Department of Obstetrics and Gynecology, \u2018Alexandra\u2019 Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9570-3969","authenticated-orcid":false,"given":"Alexandros","family":"Psarris","sequence":"additional","affiliation":[{"name":"First Department of Obstetrics and Gynecology, \u2018Alexandra\u2019 Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7229-9983","authenticated-orcid":false,"given":"Antonios","family":"Koutras","sequence":"additional","affiliation":[{"name":"First Department of Obstetrics and Gynecology, \u2018Alexandra\u2019 Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0216-3420","authenticated-orcid":false,"given":"Zacharias","family":"Fasoulakis","sequence":"additional","affiliation":[{"name":"First Department of Obstetrics and Gynecology, \u2018Alexandra\u2019 Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Prokopakis","sequence":"additional","affiliation":[{"name":"First Department of Obstetrics and Gynecology, \u2018Alexandra\u2019 Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"Varthaliti","sequence":"additional","affiliation":[{"name":"First Department of Obstetrics and Gynecology, \u2018Alexandra\u2019 Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 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