{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:22:15Z","timestamp":1760149335343,"version":"build-2065373602"},"reference-count":18,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T00:00:00Z","timestamp":1690761600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000871","name":"Mayo Clinic","doi-asserted-by":"publisher","award":["12362"],"award-info":[{"award-number":["12362"]}],"id":[{"id":"10.13039\/100000871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Introduction: Oral glucose tolerance testing is recommended for all children with CF older than 9 years, yet compliance remains poor across centers. Methods: We performed a small pilot study assessing the glycemic curves and participant satisfaction in seven children and adolescents. Results: We chose a dextrose-based candy (Nerds\u00ae) free of any fat, fiber, gelatin, or corn syrup and performed the candy OGTT 1\u20134 days following the standard oral dextrose solution OGTT. Glucose values at 120 min were similar between the candy and oral dextrose solution (p = 0.8986). Conclusions: Our small pilot suggests that a carefully selected candy alternative may result in similar glycemic OGTT when compared to the standard oral dextrose solution. However, some participants preferred the oral dextrose solution to candy due to having to consume a large volume in a short period of time. This may have significant implications as centers consider candy alternatives to increase OGTT adherence rates.<\/jats:p>","DOI":"10.3390\/children10081317","type":"journal-article","created":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T01:28:46Z","timestamp":1690766926000},"page":"1317","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oral Glucose Tolerance Testing Using Candy: A Sweet Solution to Improve Screening in Children with Cystic Fibrosis?"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-9857-5135","authenticated-orcid":false,"given":"Caroline","family":"Weeks","sequence":"first","affiliation":[{"name":"Mayo Clinic Pediatric Endocrinology Cystic Fibrosis Center, Mayo Clinic, Rochester, MN 55905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Jackson","sequence":"additional","affiliation":[{"name":"Division of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN 55905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadir","family":"Demirel","sequence":"additional","affiliation":[{"name":"Mayo Clinic Pediatric Endocrinology Cystic Fibrosis Center, Mayo Clinic, Rochester, MN 55905, USA"},{"name":"Division of Pediatric Pulmonology, Rochester, MN 55905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janelle","family":"Olson","sequence":"additional","affiliation":[{"name":"Mayo Clinic Pediatric Endocrinology Cystic Fibrosis Center, Mayo Clinic, Rochester, MN 55905, USA"},{"name":"Division of Pediatric Pulmonology, Rochester, MN 55905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicki","family":"Dean","sequence":"additional","affiliation":[{"name":"Mayo Clinic Pediatric Endocrinology Cystic Fibrosis Center, Mayo Clinic, Rochester, MN 55905, USA"},{"name":"Division of Pediatric Pulmonology, Rochester, MN 55905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caitlin","family":"Pyrz","sequence":"additional","affiliation":[{"name":"Mayo Clinic Pediatric Endocrinology Cystic Fibrosis Center, Mayo Clinic, Rochester, MN 55905, USA"},{"name":"Division of Pediatric Pulmonology, Rochester, MN 55905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4513-1800","authenticated-orcid":false,"given":"Ana L.","family":"Creo","sequence":"additional","affiliation":[{"name":"Mayo Clinic Pediatric Endocrinology Cystic Fibrosis Center, Mayo Clinic, Rochester, MN 55905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jcf.2013.06.001","article-title":"Predictors for future cystic fibrosis-related diabetes by oral glucose tolerance test","volume":"13","author":"Schmid","year":"2014","journal-title":"J. Cyst. Fibros."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.jcjd.2016.08.221","article-title":"Screening for Cystic Fibrosis-Related Diabetes: Matching Pathophysiology and Addressing Current Challenges","volume":"40","author":"Boudreau","year":"2016","journal-title":"Can. J. Diabetes"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.2337\/dc10-1768","article-title":"Clinical care guidelines for cystic fibrosis-related diabetes: A position statement of the American Diabetes Association and a clinical practice guideline of the Cystic Fibrosis Foundation, endorsed by the Pediatric Endocrine Society","volume":"33","author":"Moran","year":"2010","journal-title":"Diabetes Care"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.jcf.2011.06.001","article-title":"Use of \u201cglucola alternatives\u201d for cystic fibrosis-related diabetes screening","volume":"10","author":"Franco","year":"2011","journal-title":"J. Cyst. Fibros."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"522.e1","DOI":"10.1016\/j.ajog.2014.11.010","article-title":"Candy twists as an alternative to the glucola beverage in gestational diabetes mellitus screening","volume":"212","author":"Racusin","year":"2015","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e169","DOI":"10.2337\/dc13-1130","article-title":"Twizzlers as a cost-effective and equivalent alternative to the glucola beverage in diabetes screening","volume":"36","author":"Racusin","year":"2013","journal-title":"Diabetes Care"},{"key":"ref_7","first-page":"3","article-title":"Cystic fibrosis-related diabetes: Clinical approach and knowledge gaps","volume":"46","author":"Prentice","year":"2023","journal-title":"Paediatr. Respir. 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Available online: https:\/\/www.cfrise.com\/cystic-fibrosis-transition."},{"key":"ref_12","unstructured":"Marshall, B., Faro, A., Elbert, A., Fink, A., Sewall, A., and Loeffler, D. (2018). Cystic Fibrosis Foundation Patient Registry 2018 Annual Data Report, 2019 Cystic Fibrosis Foundation."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1080\/08870446.2016.1183008","article-title":"How patients\u2019 representations of cystic fibrosis-related diabetes inform their health behaviours","volume":"31","author":"Sylvain","year":"2016","journal-title":"Psychol. Health"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1177\/0379572119848287","article-title":"Global Patterns of Adolescent Fruit, Vegetable, Carbonated Soft Drink, and Fast-Food Consumption: A Meta-Analysis of Global School-Based Student Health Surveys","volume":"40","author":"Beal","year":"2019","journal-title":"Food Nutr. Bull."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1108\/IJHCQA-05-2014-0059","article-title":"Improving screening for diabetes in cystic fibrosis","volume":"28","author":"Abdulhamid","year":"2015","journal-title":"Int. J. Health Care Qual. Assur."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e512","DOI":"10.1542\/peds.2012-4029","article-title":"Improving screening for cystic fibrosis\u2013related diabetes at a pediatric cystic fibrosis program","volume":"132","author":"Kern","year":"2013","journal-title":"Pediatrics"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1017\/S0007114514003663","article-title":"Prospective associations between socio-economic status and dietary patterns in European children: The identification and prevention of dietary- and lifestyle-induced health effects in children and infants (IDEFICS) study","volume":"113","author":"Bammann","year":"2015","journal-title":"Br. J. Nutr."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Hebestreit, A., Intemann, T., Siani, A., De Henauw, S., Eiben, G., Kourides, Y.A., Kovacs, E., Moreno, L.A., Veidebaum, T., and Krogh, V. (2017). Dietary patterns of european children and their parents in association with family food environment: Results from the I. Family study. Nutrients, 9.","DOI":"10.3390\/nu9020126"}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/10\/8\/1317\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:22:48Z","timestamp":1760127768000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/10\/8\/1317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,31]]},"references-count":18,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,8]]}},"alternative-id":["children10081317"],"URL":"https:\/\/doi.org\/10.3390\/children10081317","relation":{},"ISSN":["2227-9067"],"issn-type":[{"type":"electronic","value":"2227-9067"}],"subject":[],"published":{"date-parts":[[2023,7,31]]}}}