{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:50:19Z","timestamp":1791867019951,"version":"4.3.4"},"reference-count":61,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:00:00Z","timestamp":1710374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background: Tibial spine avulsion fractures (TSAFs) account for approximately 14% of anterior cruciate ligament injuries. This study aims to systematically review the current evidence for the operative management of paediatric TSAFs. Methods: A search was carried out across four databases: MEDLINE, Embase, Scopus, and Google Scholar. Studies discussing the outcomes of the surgical management of paediatric TSAFs since 2000 were included. Results: Of 38 studies included for review, 13 studies reported outcomes of TSAF patients undergoing screw fixation only, and 12 studies used suture fixation only. In total, 976 patients underwent arthroscopic reduction and internal fixation (ARIF), and 203 patients underwent open reduction and internal fixation (ORIF). The risk of arthrofibrosis with the use of ARIF (p = 0.45) and screws (p = 0.74) for TSAF repair was not significant. There was a significantly increased risk of knee instability (p &lt; 0.0001), reoperation (p = 0.01), and post-operative pain (p = 0.007) with screw fixation compared to sutures. Conclusions: While the overall benefits of sutures over screws and ARIF over ORIF are unclear, there is clear preference for ARIF and suture fixation for TSAF repair in practice. We recommend large-scale comparative studies to delineate long-term outcomes for various TSAF fixation techniques.<\/jats:p>","DOI":"10.3390\/children11030345","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T09:32:30Z","timestamp":1710495150000},"page":"345","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Tibial Spine Avulsion Fractures in Paediatric Patients: A Systematic Review and Meta-Analysis of Surgical Management"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2702-9404","authenticated-orcid":false,"given":"Mehak","family":"Chandanani","sequence":"first","affiliation":[{"name":"School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2354-7530","authenticated-orcid":false,"given":"Raian","family":"Jaibaji","sequence":"additional","affiliation":[{"name":"University College London, London WC1E 6BT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monketh","family":"Jaibaji","sequence":"additional","affiliation":[{"name":"Health Education North East, Newcastle upon Tyne NE15 8NY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Volpin","sequence":"additional","affiliation":[{"name":"NHS Grampian, Aberdeen AB15 6RE, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,14]]},"reference":[{"key":"ref_1","unstructured":"Poncet, A. (1875). Arrachement de l\u2019epine du tibia a l\u2019insertion du ligament croise anterieur. Bull Mem. Soc. Chir. Paris., 883\u2013884."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1302\/0301-620X.74B6.1447245","article-title":"Fracture of the tibial spine in adults and children. A review of 31 cases","volume":"74-B","author":"Kendall","year":"1992","journal-title":"J. Bone Joint Surg. Br."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Sapre, V., and Bagari, V. (2013). Regional Arthroscopy, InTech.","DOI":"10.5772\/45960"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"209","DOI":"10.2106\/00004623-195941020-00002","article-title":"Fracture of the Intercondylar Eminence of the Tibia","volume":"41","author":"Meyers","year":"1959","journal-title":"J. Bone Jt. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.2106\/00004623-197759080-00022","article-title":"Avulsion fracture of the tibial eminence: Treatment by open reduction and pinning","volume":"59","author":"Zaricznyj","year":"1977","journal-title":"J Bone Joint Surg. Am."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1007\/s00167-018-5039-7","article-title":"A new, MRI-based classification system for tibial spine fractures changes clinical treatment recommendations when compared to Myers and Mckeever","volume":"27","author":"Green","year":"2019","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_7","unstructured":"Meyers, A.L., Tiwari, V., and Nelson, R. (2024). Tibial Eminence Fractures, StatPearls."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s11832-014-0571-6","article-title":"Tibial eminence fractures in the paediatric population: A systematic review","volume":"8","author":"Coyle","year":"2014","journal-title":"J. Child Orthop."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s13643-016-0384-4","article-title":"Rayyan\u2014A web and mobile app for systematic reviews","volume":"5","author":"Ouzzani","year":"2016","journal-title":"Syst. Rev."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1046\/j.1445-2197.2003.02748.x","article-title":"Methodological Index for Non-Randomized Studies (MINORS): Development and Validation of A New Instrument","volume":"73","author":"Slim","year":"2003","journal-title":"ANZ J. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1007\/s00264-014-2462-3","article-title":"Neglected ununited tibial eminence fractures in the skeletally immature: Arthroscopic management","volume":"38","author":"Abdelkafy","year":"2014","journal-title":"Int. Orthop."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/s00167-015-3844-9","article-title":"Absorbable and non-absorbable suture fixation results in similar outcomes for tibial eminence fractures in children and adolescents","volume":"24","author":"Brunner","year":"2016","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_13","first-page":"571","article-title":"Mid-term Outcomes of Arthroscopic Suture Fixation Technique in Tibial Spine Fractures in the Pediatric Population","volume":"27","author":"Yagar","year":"2020","journal-title":"Turk. J. Trauma Emerg. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"232596711988196","DOI":"10.1177\/2325967119881961","article-title":"Suture Versus Screw Fixation of Tibial Spine Fractures in Children and Adolescents: A Comparative Study","volume":"7","author":"Callanan","year":"2019","journal-title":"Orthop. J. Sports Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.otsr.2010.01.012","article-title":"Tibial intercondylar eminence fractures in children: The long-term perspective","volume":"96","author":"Casalonga","year":"2010","journal-title":"Orthop. Traumatol. Surg. Res."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"103270","DOI":"10.1016\/j.otsr.2022.103270","article-title":"Arthroscopic suture-fixation of anterior tibial intercondylar eminence fractures by retensioning of the ACL and hollowing of the tibial footprint: Objective and subjective clinical results in a paediatric population","volume":"108","author":"Chalopin","year":"2022","journal-title":"Orthop. Traumatol. Surg. Res."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1007\/s00167-015-3707-4","article-title":"Cartilaginous tibial eminence fractures in children: Which recommendations for management of this new entity?","volume":"24","author":"Chotel","year":"2016","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"103021","DOI":"10.1016\/j.otsr.2021.103021","article-title":"Anatomical fixation of tibial intercondylar eminence fractures in children using a threaded pin with an adjustable lock","volume":"108","author":"Schneider","year":"2022","journal-title":"Orthop. Traumatol. Surg. Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1097\/BPO.0000000000000356","article-title":"Results of Displaced Pediatric Tibial Spine Fractures: A Comparison Between Open, Arthroscopic, and Closed Management","volume":"35","author":"Edmonds","year":"2015","journal-title":"J. Pediatr. Orthop."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1177\/145749691009900109","article-title":"Pediatric tibial eminence fractures: Arthroscopic treatment using K-wire","volume":"99","author":"Furlan","year":"2010","journal-title":"Scand. J. Surg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s00167-009-0733-0","article-title":"Physeal sparing arthroscopic fixation of displaced tibial eminence fractures: A new surgical technique","volume":"17","author":"Hirschmann","year":"2009","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"23259671231176991","DOI":"10.1177\/23259671231176991","article-title":"Long-term Outcomes of Tibial Spine Avulsion Fractures After Open Reduction with Osteosuturing Versus Arthroscopic Screw Fixation: A Multicenter Comparative Study","volume":"11","author":"Turati","year":"2023","journal-title":"Orthop. J. Sports Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1177\/230949901101900306","article-title":"Displaced tibial intercondylar eminence fractures","volume":"19","author":"Kieser","year":"2011","journal-title":"J. Orthop. Surg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"659","DOI":"10.4055\/jkoa.2007.42.5.659","article-title":"Arthroscopic Internal Fixation of Displaced Tibial Eminence Fracture Using Cannulated Screw","volume":"42","author":"Kim","year":"2007","journal-title":"J. Korean Orthop. Assoc."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1007\/s00402-021-03860-w","article-title":"Satisfactory outcome following arthroscopic fixation of tibial intercondylar eminence fractures in children and adolescents using bioabsorbable nails","volume":"141","author":"Kristinsson","year":"2021","journal-title":"Arch. Orthop. Trauma Surg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1177\/0363546508330133","article-title":"Arthroscopic Fixation of Anterior Tibial Spine Fractures with Bioabsorbable Nails in Skeletally Immature Patients","volume":"37","author":"Liljeros","year":"2009","journal-title":"Am. J. Sports Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1097\/BPB.0b013e32830b61f4","article-title":"Surgical management of type II tibial intercondylar eminence fractures in children","volume":"17","author":"Franck","year":"2008","journal-title":"J. Pediatr. Orthop. B"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/BPB.0000000000000223","article-title":"Arthroscopic fixation with intra-articular button for tibial intercondylar eminence fractures in skeletally immature patients","volume":"25","author":"Memisoglu","year":"2016","journal-title":"J. Pediatr. Orthop. B"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/BPB.0000000000000459","article-title":"Outcomes after arthroscopic fixation of tibial eminence fractures with bioabsorbable nails in skeletally immature patients","volume":"27","author":"Momaya","year":"2018","journal-title":"J. Pediatr. Orthop. B"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.otsr.2016.02.004","article-title":"Arthroscopic treatment of intercondylar eminence fractures with intraepiphyseal screws in children and adolescents","volume":"102","author":"Najdi","year":"2016","journal-title":"Orthop. Traumatol. Surg. Res."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00264-008-0697-6","article-title":"Clinical and radiological results of arthroscopically treated tibial spine fractures in childhood","volume":"33","author":"Perugia","year":"2009","journal-title":"Int. Orthop."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Russu, O.M., Pop, T.S., Ciorcila, E., Gergely, I., Zuh, S.-G., Tr\u00e2mbi\u021ba\u0219, C., Borodi, P.G., Incze-Bartha, Z., Feier, A.M., and Georgeanu, V.A. (2021). Arthroscopic Repair in Tibial Spine Avulsion Fractures Using Polyethylene Terephthalate Suture: Good to Excellent Results in Pediatric Patients. J. Pers. Med., 11.","DOI":"10.3390\/jpm11050434"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.injury.2017.11.013","article-title":"Management and outcomes of isolated paediatric tibial spine fractures","volume":"49","author":"Scrimshire","year":"2018","journal-title":"Injury"},{"key":"ref_34","first-page":"90","article-title":"An analysis of different types of surgical fixation for avulsion fractures of the anterior tibial spine","volume":"74","author":"Sharma","year":"2008","journal-title":"Acta Orthop. Belg."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/BPO.0000000000002049","article-title":"A Multicenter Comparison of Open Versus Arthroscopic Fixation for Pediatric Tibial Spine Fractures","volume":"42","author":"Shimberg","year":"2022","journal-title":"J. Pediatr. Orthop."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Shin, C.H., Lee, D.J., Choi, I.H., Cho, T.-J., and Yoo, W.J. (2018). Clinical and radiological outcomes of arthroscopically assisted cannulated screw fixation for tibial eminence fracture in children and adolescents. BMC Musculoskelet. Disord., 19.","DOI":"10.1186\/s12891-018-1960-7"},{"key":"ref_37","first-page":"80","article-title":"Arthroscopic Fixation of Tibial Spine Avulsion in Skeletally Immature: The Technique","volume":"7","author":"Sinha","year":"2017","journal-title":"J. Orthop. Case Rep."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/BPB.0b013e32833a5f4d","article-title":"Intercondylar eminence avulsion fracture in children: Long-term follow-up of 14 cases at the end of skeletal growth","volume":"19","author":"Tudisco","year":"2010","journal-title":"J. Pediatr. Orthop. B"},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Uboldi, F.M., Trezza, P., Panuccio, E., and Memeo, A. (2022). Arthroscopic treatment of tibial intercondylar eminence fractures in skeletally immature patients with bioabsorbable nails. La Pediatr. Medica E Chir., 44.","DOI":"10.4081\/pmc.2022.299"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.arthro.2008.07.007","article-title":"Arthroscopic Fixation of Displaced Tibial Eminence Fractures: A New Growth Plate\u2013Sparing Method","volume":"24","author":"Vega","year":"2008","journal-title":"Arthrosc. J. Arthrosc. Relat. Surg."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/BPO.0000000000000476","article-title":"Open Versus Arthroscopic Reduction for Tibial Eminence Fracture Fixation in Children","volume":"36","author":"Watts","year":"2016","journal-title":"J. Pediatr. Orthop."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.knee.2013.12.004","article-title":"Arthroscopic treatment of tibial spine fracture in children with a cannulated Herbert screw","volume":"21","author":"Wiegand","year":"2014","journal-title":"Knee"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Wiktor, \u0141., and Tomaszewski, R. (2022). Results of Anterior Cruciate Ligament Avulsion Fracture by Treatment Using Bioabsorbable Nails in Children and Adolescents. Children, 9.","DOI":"10.3390\/children9121897"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1007\/s00167-010-1341-8","article-title":"The arthroscopic treatment of displaced tibial spine fractures in children and adolescents using Meniscus Arrows\u00ae","volume":"19","author":"Wouters","year":"2011","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1007\/s00402-017-2770-3","article-title":"Arthroscopic fixation of pediatric tibial eminence fractures using suture anchors: A mid-term follow-up","volume":"137","author":"Xu","year":"2017","journal-title":"Arch. Orthop. Trauma Surg."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Zhang, L., Zhang, L., Zheng, J., Ren, B., Kang, X., Zhang, X., and Dang, X. (2020). Arthroscopic tri-pulley Technology reduction and internal fixation of pediatric Tibial Eminence fracture: A retrospective analysis. BMC Musculoskelet. Disord., 21.","DOI":"10.1186\/s12891-020-03421-z"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"639270","DOI":"10.3389\/fsurg.2021.639270","article-title":"Arthroscopically Assisted Cannulated Screw Fixation for Treating Type III Tibial Intercondylar Eminence Fractures: A Short-Term Retrospective Controlled Study","volume":"8","author":"Zheng","year":"2021","journal-title":"Front. Surg."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1007\/s00264-023-05756-3","article-title":"Arthroscopic percutaneous pullout suture transverse tunnel technique repair for tibial spine fractures in skeletally immature patients","volume":"47","author":"Zhou","year":"2023","journal-title":"Int. Orthop."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1179544118809050","DOI":"10.1177\/1179544118809050","article-title":"A Narrative Review on Avulsion Fractures of the Upper and Lower Limbs","volume":"11","author":"Vannabouathong","year":"2018","journal-title":"Clin. Med. Insights Arthritis Musculoskelet. Disord."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"3208","DOI":"10.1177\/0363546520957666","article-title":"Tibial Spine Fractures: How Much Are We Missing Without Pretreatment Advanced Imaging? A Multicenter Study","volume":"48","author":"Shimberg","year":"2020","journal-title":"Am. J. Sports Med."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1177\/03635465020300051201","article-title":"Partial Tears of the Anterior Cruciate Ligament in Children and Adolescents","volume":"30","author":"Kocher","year":"2002","journal-title":"Am. J. Sports Med."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"232596712210793","DOI":"10.1177\/23259671221079338","article-title":"Sensitivity and Specificity of MRI in Diagnosing Concomitant Meniscal Injuries with Pediatric and Adolescent Acute ACL Tears","volume":"10","author":"Dawkins","year":"2022","journal-title":"Orthop. J. Sports Med."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.otsr.2011.07.010","article-title":"The concordance of MRI and arthroscopy in traumatic meniscal lesions in children","volume":"97","author":"Bouju","year":"2011","journal-title":"Orthop. Traumatol. Surg. Res."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1097\/BPO.0b013e31820fc6b8","article-title":"Meniscal Pathology Associated with Acute Anterior Cruciate Ligament Tears in Patients with Open Physes","volume":"31","author":"Samora","year":"2011","journal-title":"J. Pediatr. Orthop."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1177\/0363546513508538","article-title":"Treatment and Management Outcomes of Tibial Eminence Fractures in Pediatric Patients","volume":"42","author":"Gans","year":"2014","journal-title":"Am. J. Sports Med."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"e661","DOI":"10.1097\/BPO.0000000000001331","article-title":"Confirming the Presence of Unrecognized Meniscal Injuries on Magnetic Resonance Imaging in Pediatric and Adolescent Patients with Anterior Cruciate Ligament Tears","volume":"39","author":"Munger","year":"2019","journal-title":"J. Pediatr. Orthop."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1177\/03635465231172770","article-title":"Extension of Tibial Spine Fractures Beyond the Tibial Spine: An MRI Analysis of 54 Patients","volume":"51","author":"Cirrincione","year":"2023","journal-title":"Am. J. Sports Med."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"68","DOI":"10.55275\/JPOSNA-2020-68","article-title":"Tibial Spine Fracture Management\u2014Technical Tips and Tricks from the Tibial Spine Fracture Research Interest Group","volume":"2","author":"Kushare","year":"2020","journal-title":"J. Pediatr. Orthop. Soc. N. Am."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.jisako.2023.06.001","article-title":"Tibial spine fractures: State of the art","volume":"8","author":"Salvato","year":"2023","journal-title":"J. ISAKOS"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1177\/0363546506294677","article-title":"Biomechanical Evaluation of Different Fixation Methods for Tibial Eminence Fractures","volume":"35","author":"Eggers","year":"2007","journal-title":"Am. J. Sports Med."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/bmb\/ldw018","article-title":"Arthroscopic treatment of tibial eminence fracture: A systematic review of different fixation methods","volume":"118","author":"Osti","year":"2016","journal-title":"Br. Med. Bull."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/11\/3\/345\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:13:32Z","timestamp":1760105612000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/11\/3\/345"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,14]]},"references-count":61,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,3]]}},"alternative-id":["children11030345"],"URL":"https:\/\/doi.org\/10.3390\/children11030345","relation":{},"ISSN":["2227-9067"],"issn-type":[{"value":"2227-9067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,14]]}}}