{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:43:08Z","timestamp":1791902588674,"version":"4.3.4"},"reference-count":34,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,4,7]],"date-time":"2024-04-07T00:00:00Z","timestamp":1712448000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>We conducted a two-year retrospective evaluation of infants aged under two years with a confirmed, clinical, or suspected diagnosis of scabies in a healthcare center in Alicante (Spain) to determine possible factors associated with diagnostic delay and poor treatment response. We collected epidemiological, clinical, diagnostic, and treatment variables. After describing our findings as mean values and percentages, we compared categorical variables using the Student\u2019s t-test and the Mann\u2013Whitney U test, and we compared continuous variables with the Chi2 test and Pearson\u2019s correlation coefficient. We included 51 infants (19 boys and 32 girls) with a mean age of 15 months. The main source of contagion was the family; half of the infants lived with four or more people. According to the International Consensus Criteria for the Diagnosis of Scabies, confirmed scabies was diagnosed in 45% of cases and clinical scabies in 47%, and 45% of cases had a diagnostic delay. Lesions mainly affected the hands, feet, and trunk, with papules in 92% of cases and burrows in 55%. The predominant symptoms were pruritus (94%) and irritability (69%). Regarding treatment, 98% of the infants received topical permethrin and 35% received oral ivermectin. Treatment failed in 76% of infants. Living in large family units was associated with a higher risk of contagion and therapeutic failure. Diagnostic delay was associated with previous misdiagnosis.<\/jats:p>","DOI":"10.3390\/children11040443","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T10:11:55Z","timestamp":1712571115000},"page":"443","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Scabies in Infants: Series of 51 Cases"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0050-6178","authenticated-orcid":false,"given":"Isabel","family":"Betlloch-Mas","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Miguel Hern\u00e1ndez University, Carretera Alicante-Valencia N-332, 03550 Sant Joan d\u2019Alacant, Spain"},{"name":"Department of Dermatology, Dr. Balmis General University Hospital, 03010 Alicante, Spain"},{"name":"ISABIAL Research Institute, 03010 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4185-0524","authenticated-orcid":false,"given":"Elena","family":"Boluda-Verd\u00fa","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Miguel Hern\u00e1ndez University, Carretera Alicante-Valencia N-332, 03550 Sant Joan d\u2019Alacant, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3339-7125","authenticated-orcid":false,"given":"Noelia","family":"Jara-Rico","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Dr. Balmis General University Hospital, 03010 Alicante, Spain"},{"name":"ISABIAL Research Institute, 03010 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6680-9716","authenticated-orcid":false,"given":"Ver\u00f3nica","family":"S\u00e1nchez-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Dr. Balmis General University Hospital, 03010 Alicante, Spain"},{"name":"ISABIAL Research Institute, 03010 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7519-2412","authenticated-orcid":false,"given":"Laura","family":"Berbegal-De Gracia","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Dr. Balmis General University Hospital, 03010 Alicante, Spain"},{"name":"ISABIAL Research Institute, 03010 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3374-4623","authenticated-orcid":false,"given":"Eusebi","family":"Chiner-Vives","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, San Juan de Alicante University Hospital, 03010 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,7]]},"reference":[{"key":"ref_1","first-page":"33","article-title":"Scabies: A Neglected Global Disease","volume":"16","author":"Leung","year":"2020","journal-title":"Curr. 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