{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:15:57Z","timestamp":1760145357097,"version":"build-2065373602"},"reference-count":67,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T00:00:00Z","timestamp":1720483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background: Nasal high-frequency oscillatory ventilation (nHFOV) has emerged as an effective initial and rescue noninvasive respiratory support mode for preterm infants with respiratory distress syndrome (RDS); however, little is known about nHFOV use in Romanian neonatal intensive care units (NICUs). Objectives: We aimed to identify the usage extent and clinical application of nHFOV in Romania. Methods: A structured web-based questionnaire was designed to find the rate of nHFOV use and knowledge of this new method of noninvasive respiratory support in Romanian level III NICUs. Using multiple-choice, open-ended, and yes\/no questions, we collected information on the NICU\u2019s size, noninvasive respiratory support modes used, nHFOV use, indications, settings, nasal interfaces, secondary effects, and equipment used. Descriptive statistics and comparisons were performed using IBM SPSS Statistics 26.0. Results: A total of 21\/23 (91.3%) leaders from level III NICUs (median [IQR] number of beds of 10 [10\u201317.5]) responded to the survey. The most frequently used noninvasive ventilation modes were CPAP mode on mechanical ventilators (76.2%), followed by NIPPV (76.2%); heated, humidified high-flow nasal cannula (HHHFNC) (61.9%); and nHFOV (11\/21 units; 52.4%). A total of 5\/11 units reported frequent nHFOV use (in two or more newborns\/month) in both term and preterm infants. The main indications reported for nHFOV use were CPAP failure (90.9%), hypercapnia (81.8%), and bronchopulmonary dysplasia (72.7%). Face\/nasal masks and short binasal prongs are the most commonly used nasal interfaces (90.9% and 72.7%, respectively). Air leaks at the interface level (90.9%), thick secretions (81.8%), and airway obstruction (63.6%) were the most frequently mentioned adverse effects of nHFOV. Only three of the NICUs had a written protocol for nHFOV use. Most units not yet using nHFOV cited lack of equipment, experience, training, or insufficient information and evidence for the clinical use and outcome of nHFOV use in neonates as the main reasons for not implementing this noninvasive respiratory mode. Conclusions: Our survey showed that nHFOV is already used in more than half of the Romanian level III NICUs to support term and preterm infants with respiratory distress despite a lack of consensus regarding indications and settings during nHFOV.<\/jats:p>","DOI":"10.3390\/children11070836","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T13:22:36Z","timestamp":1720531356000},"page":"836","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Nasal High-Frequency Oscillatory Ventilation Use in Romanian Neonatal Intensive Care Units\u2014The Results of a Recent Survey"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2233-4218","authenticated-orcid":false,"given":"Maria Livia","family":"Ognean","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Lucian Blaga University, 550169 Sibiu, Romania"},{"name":"Neonatology Department, Clinical County Emergency Hospital, 550245 Sibiu, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anca","family":"Bivoleanu","sequence":"additional","affiliation":[{"name":"Regional Neonatal Intensive Care Unit, Grigore T. Popa University of Medicine and Pharmacy, Cuza-Voda Clinical Hospital of Obstetrics and Gynaecology, 700038 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2498-5433","authenticated-orcid":false,"given":"Manuela","family":"Cucerea","sequence":"additional","affiliation":[{"name":"Department of Neonatology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology, 540142 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radu","family":"Gali\u0219","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Emergency County Hospital Bihor, 410167 Oradea, Romania"},{"name":"Doctoral School, Poznan University of Medical Sciences, 60-512 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4629-5820","authenticated-orcid":false,"given":"Ioana","family":"Ro\u0219ca","sequence":"additional","affiliation":[{"name":"Neonatology Department, Panait Sirbu Maternity Hospital, 050786 Bucharest, Romania"},{"name":"Midwifery and Nursing Faculty, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5878-1407","authenticated-orcid":false,"given":"Monica","family":"Surdu","sequence":"additional","affiliation":[{"name":"Neonatology Department, County Emergency Hospital Constan\u021ba, 900591 Constanta, Romania"},{"name":"Faculty of Medicine, Ovidius University Constanta, 900470 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia-Maria","family":"Stoicescu","sequence":"additional","affiliation":[{"name":"\u201cAlessandrescu-Rusescu\u201d National Institute for Mother and Child Health, 010919 Bucharest, Romania"},{"name":"Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7358-601X","authenticated-orcid":false,"given":"Rangasamy","family":"Ramanathan","sequence":"additional","affiliation":[{"name":"Division of Neonatal Medicine, Cedars Sinai Guerin Children\u2019s, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3151","DOI":"10.1007\/s00431-021-04084-1","article-title":"Nasal HFOV versus nasal IPPV as a post-extubation respiratory support in preterm infants\u2014A randomised controlled trial","volume":"180","author":"Seth","year":"2021","journal-title":"Eur. J. Pediatr."},{"key":"ref_2","first-page":"CD005384","article-title":"Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure (NCPAP) for preterm infants","volume":"12","author":"Lemyre","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"F565","DOI":"10.1136\/archdischild-2016-310664","article-title":"Non-invasive high-frequency oscillatory ventilation in neonates: Review of physiology, biology and clinical data","volume":"101","year":"2016","journal-title":"Arch. Dis. Child.-Fetal Neonatal Ed."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.clp.2021.07.006","article-title":"Nasal High-Frequency Ventilation","volume":"48","author":"Centorrino","year":"2021","journal-title":"Clin. Perinatol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1038\/s41372-021-01104-8","article-title":"Nasal high-frequency jet ventilation (NHFJV) as a novel means of respiratory support in extremely low birth weight infants","volume":"41","author":"Keel","year":"2021","journal-title":"J. Perinatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.siny.2016.02.001","article-title":"High-frequency ventilation for non-invasive respiratory support of neonates","volume":"21","author":"Yoder","year":"2016","journal-title":"Semin. Fetal Neonatal Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.chest.2019.01.014","article-title":"Nasal High-Frequency Oscillatory Ventilation in Preterm Infants With Respiratory Distress Syndrome and ARDS After Extubation: A Randomized Controlled Trial","volume":"155","author":"Chen","year":"2019","journal-title":"Chest"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s12931-019-1023-0","article-title":"Noninvasive high-frequency oscillatory ventilation as respiratory support in preterm infants: A meta-analysis of randomized controlled trials","volume":"20","author":"Li","year":"2019","journal-title":"Respir. Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00431-021-04190-0","article-title":"Nasal high-frequency oscillatory ventilation versus nasal continuous positive airway pressure as primary respiratory support strategies for respiratory distress syndrome in preterm infants: A systematic review and meta-analysis","volume":"181","author":"Li","year":"2022","journal-title":"Eur. J. Pediatr."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1159\/000515226","article-title":"Nasal High-Frequency Oscillatory Ventilation in Preterm Infants with Moderate Respiratory Distress Syndrome: A Multicenter Randomized Clinical Trial","volume":"118","author":"Zhu","year":"2021","journal-title":"Neonatology"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e33142","DOI":"10.1097\/MD.0000000000033142","article-title":"The clinical effects of two non-invasive ventilation modes on premature infants with respiratory distress syndrome: A randomized controlled trial","volume":"102","author":"Wang","year":"2023","journal-title":"Medicine"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1136\/archdischild-2023-325681","article-title":"Non-invasive high-frequency oscillatory ventilation (NHFOV) versus nasal continuous positive airway pressure (NCPAP) for preterm infants: A systematic review and meta-analysis","volume":"109","author":"Wang","year":"2024","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.5114\/aoms.2020.93541","article-title":"Three non-invasive ventilation strategies for preterm infants with respiratory distress syndrome: A propensity score analysis","volume":"16","author":"Cao","year":"2020","journal-title":"Arch. Med. Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1001\/jamapediatrics.2022.0710","article-title":"Noninvasive High-Frequency Oscillatory Ventilation vs Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation as Postextubation Support for Preterm Neonates in China: A Randomized Clinical Trial","volume":"176","author":"Zhu","year":"2022","journal-title":"JAMA Pediatr."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Mei, Z., Ming, L., Wu, Z., and Zhu, Y. (2023). Use of NHFOV vs. NIPPV for the respiratory support of preterm newborns after extubation: A meta-analysis. Front. Pediatr., 10.","DOI":"10.3389\/fped.2022.1063387"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"300060520984915","DOI":"10.1177\/0300060520984915","article-title":"Non-invasive high-frequency oscillatory ventilation in preterm infants after extubation: A randomized, controlled trial","volume":"49","author":"Li","year":"2021","journal-title":"J. Int. Med. Res."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"e2321644","DOI":"10.1001\/jamanetworkopen.2023.21644","article-title":"Effectiveness of Nasal Continuous Positive Airway Pressure vs. Nasal Intermittent Positive Pressure Ventilation vs. Noninvasive High-Frequency Oscillatory Ventilation as Support after Extubation of Neonates Born Extremely Preterm or with More Severe Respiratory Failure: A Secondary Analysis of a Randomized Clinical Trial","volume":"6","author":"Zhu","year":"2023","journal-title":"JAMA Netw. Open"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"23","DOI":"10.24953\/turkjped.2021.01.003","article-title":"Comparison of four different non-invasive respiratory support techniques as primary respiratory support in preterm infants","volume":"63","year":"2021","journal-title":"Turk. J. Pediatr."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1002\/ppul.26244","article-title":"Noninvasive high-frequency oscillatory ventilation versus nasal intermittent positive pressure ventilation for preterm infants as an extubation support: A systematic review and meta-analysis","volume":"58","author":"Wang","year":"2023","journal-title":"Pediatr. Pulmonol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/S0140-6736(10)60278-4","article-title":"Elective high-frequency oscillatory versus conventional ventilation in preterm infants: A systematic review and meta-analysis of individual patients\u2019 data","volume":"375","author":"Cools","year":"2010","journal-title":"Lancet"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jpeds.2018.05.029","article-title":"The Effect of Noninvasive High-Frequency Oscillatory Ventilation on Desaturations and Bradycardia in Very Preterm Infants: A Randomized Crossover Trial","volume":"201","author":"Lorenz","year":"2018","journal-title":"J. Pediatr."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Sammour, I., and Karnati, S. (2020). Non-invasive Respiratory Support of the Premature Neonate: From Physics to Bench to Practice. Front. Pediatr., 8.","DOI":"10.3389\/fped.2020.00214"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1111\/j.1651-2227.2008.01016.x","article-title":"Should nasal high-frequency ventilation be used in preterm infants?","volume":"97","author":"Carlo","year":"2008","journal-title":"Acta Paediatr."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1159\/000369120","article-title":"Laryngeal muscle activity during nasal high-frequency oscillatory ventilation in nonsedated newborn lambs","volume":"107","author":"Samson","year":"2015","journal-title":"Neonatology"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/pr.2013.254","article-title":"High-frequency nasal ventilation for 21 d maintains gas exchange with lower respiratory pressures and promotes alveolarization in preterm lambs","volume":"75","author":"Null","year":"2014","journal-title":"Pediatr. Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jbiomech.2010.09.002","article-title":"Dynamic surface tension of natural surfactant extract under superimposed oscillations","volume":"44","author":"Reddy","year":"2011","journal-title":"J. Biomech."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1203\/PDR.0b013e31822f58a1","article-title":"Mechanism of reduced lung injury by high-frequency nasal ventilation in a preterm lamb model of neonatal chronic lung disease","volume":"70","author":"Rehan","year":"2011","journal-title":"Pediatr. Res."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1164\/ajrccm.162.5.9912145","article-title":"High-frequency oscillatory ventilation: Effects on lung function, mechanics, and airway cytokines in the immature baboon model for neonatal chronic lung disease","volume":"162","author":"Yoder","year":"2000","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1164\/rccm.202007-2701OC","article-title":"Transmission of Oscillatory Volumes into the Preterm Lung during Noninvasive High-Frequency Ventilation","volume":"203","author":"Gaertner","year":"2021","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1136\/archdischild-2021-322990","article-title":"Lung volume distribution in preterm infants on non-invasive high-frequency ventilation","volume":"107","author":"Gaertner","year":"2022","journal-title":"Arch. Dis. Child.-Fetal Neonatal Ed."},{"key":"ref_31","unstructured":"(2024, May 01). Ordinul Ministrului S\u0103n\u0103t\u0103\u0163ii \u015fi Familiei nr. 910 Privind Criteriile de Ierarhizare a Sec\u0163iilor de Spital de Specialitate Obstetric\u0103, Ginecologie \u015fi Neonatologie. Monitorul Oficial al Rom\u00e2niei. Available online: http:\/\/www.sant.ro\/informatii-utile\/criteriile-de-ierarhizare-a-sectiilor-de-spital-de-specialitate-obstetrica-ginecologie-si-neonatologie\/OMS910-OMS272.pdf."},{"key":"ref_32","unstructured":"(2024, May 01). Ordinului Ministrului S\u0103n\u0103t\u0103\u0163ii nr. 323\/18.04.2011 Privind Aprobarea Metodologiei \u015fi a Criteriilor Minime Obligatorii Pentru Clasificarea Spitalelor \u00een Func\u0163ie de Competen\u0163\u0103 Monitorul Oficial al Rom\u00e2niei. Available online: https:\/\/ms.ro\/media\/documents\/ORDIN_Nr._323_2011_forma_la_data_de_20.11.2023.pdf."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00431-014-2419-y","article-title":"Nasal high-frequency oscillation ventilation in neonates: A survey in five European countries","volume":"174","author":"Fischer","year":"2015","journal-title":"Eur. J. Pediatr."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/apa.13644","article-title":"Survey of noninvasive respiratory support practices in Canadian neonatal intensive care units","volume":"106","author":"Mukerji","year":"2017","journal-title":"Acta Paediatr."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s13052-019-0639-5","article-title":"Neonatal respiratory support strategies for the management of extremely low gestational age infants: An Italian survey","volume":"45","author":"Petrillo","year":"2019","journal-title":"Ital. J. Pediatr."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Cucerea, M., Simon, M., Stoicescu, S.M., Blaga, L.D., Gali\u0219, R., Stamatin, M., Olariu, G., and Ognean, M.L. (2024). Neonatal Resuscitation Practices in Romania: A Survey of the Romanian Association of Neonatology (ANR) and the Union of European Neonatal and Perinatal Societies (UENPS). J. Crit. Care Med., 10.","DOI":"10.2478\/jccm-2024-0010"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s13052-022-01260-3","article-title":"Neonatal resuscitation practices in Italy: A survey of the Italian Society of Neonatology (SIN) and the Union of European Neonatal and Perinatal Societies (UENPS)","volume":"48","author":"Gizzi","year":"2022","journal-title":"Ital. J. Pediatr."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1007\/s00134-010-2054-7","article-title":"Noninvasive high frequency oscillatory ventilation through nasal prongs: Bench evaluation of efficacy and mechanics","volume":"36","author":"Carnielli","year":"2010","journal-title":"Intensive Care Med."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1002\/ppul.22511","article-title":"Effect of amplitude and inspiratory time in a bench model of non-invasive HFOV through nasal prongs","volume":"47","author":"Piastra","year":"2012","journal-title":"Pediatr. Pulmonol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"4173","DOI":"10.1007\/s00431-023-05107-9","article-title":"Variation in delivery room management of preterm infants across Europe: A survey of the Union of European Neonatal and Perinatal Societies","volume":"182","author":"Gizzi","year":"2023","journal-title":"Eur. J. Pediatr."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1159\/000528914","article-title":"European Consensus Guidelines on the Management of Respiratory Distress Syndrome: 2022 Update","volume":"120","author":"Sweet","year":"2023","journal-title":"Neonatology"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"F61","DOI":"10.1136\/fn.79.1.F61","article-title":"Nasal high frequency ventilation in neonates with moderate respiratory insufficiency","volume":"79","author":"Brouwer","year":"1998","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1055\/s-0040-1718738","article-title":"Noninvasive High-Frequency Oscillatory Ventilation: A Retrospective Chart Review","volume":"39","author":"Ali","year":"2022","journal-title":"Am. J. Perinatol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1111\/j.1651-2227.2008.00900.x","article-title":"Nasal high-frequency ventilation for premature infants","volume":"97","author":"Colaizy","year":"2008","journal-title":"Acta Paediatr."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1055\/s-0034-1381317","article-title":"Use of noninvasive high-frequency ventilation in the neonatal intensive care unit: A retrospective review","volume":"30","author":"Mukerji","year":"2015","journal-title":"Am. J. Perinatol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/ppul.23534","article-title":"Leakage in nasal high-frequency oscillatory ventilation improves carbon dioxide clearance-A bench study","volume":"52","author":"Klotz","year":"2017","journal-title":"Pediatr. Pulmonol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.pedneo.2019.09.014","article-title":"Non-invasive respiratory support for preterm infants following extubation from mechanical ventilation. A narrative review and guideline suggestion","volume":"61","author":"Shehadeh","year":"2020","journal-title":"Pediatr. Neonatol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.12669\/pjms.38.5.5939","article-title":"Noninvasive high-frequency oscillatory ventilation versus bi-level positive pressure ventilation in premature infants with respiratory failure: A retrospective study","volume":"38","author":"Chen","year":"2022","journal-title":"Pak. J. Med. Sci."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Shi, Y., De Luca, D., and NASal OscillatioN post-Extubation (NASONE) Study Group (2019). Continuous positive airway pressure (CPAP) vs noninvasive positive pressure ventilation (NIPPV) vs noninvasive high frequency oscillation ventilation (NHFOV) as post-extubation support in preterm neonates: Protocol for an assessor-blinded, multicenter, randomized controlled trial. BMC Pediatr., 19.","DOI":"10.1186\/s12887-019-1625-1"},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Fischer, H.S., B\u00fchrer, C., and Czernik, C. (2019). Hazards to avoid in future neonatal studies of nasal high-frequency oscillatory ventilation: Lessons from an early terminated trial. BMC Res. Notes, 12.","DOI":"10.1186\/s13104-019-4268-2"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jpeds.2018.09.062","article-title":"The Impact of Time Interval between Extubation and Reintubation on Death or Bronchopulmonary Dysplasia in Extremely Preterm Infants","volume":"205","author":"Shalish","year":"2019","journal-title":"J. Pediatr."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1002\/ppul.23755","article-title":"Noninvasive high-frequency oscillatory ventilation versus nasal continuous positive airway pressure in preterm infants with moderate-severe respiratory distress syndrome: A preliminary report","volume":"52","author":"Zhu","year":"2017","journal-title":"Pediatr. Pulmonol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"22","DOI":"10.21292\/2078-5658-2020-17-6-22-30","article-title":"Non-invasive ventilation provides adequate gas exchange minimizing pulmonary and extrapulmonary complications","volume":"17","author":"Aleksandrovich","year":"2020","journal-title":"Messenger Anesthesiol. Resusc."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Lai, S.H., Xie, Y.L., Chen, Z.Q., Chen, R., Cai, W.H., Wu, L.C., Lin, Y.F., and Zheng, Y.R. (2022). Non-invasive High-Frequency Oscillatory Ventilation as Initial Respiratory Support for Preterm Infants With Respiratory Distress Syndrome. Front. Pediatr., 9.","DOI":"10.3389\/fped.2021.792160"},{"key":"ref_55","first-page":"11","article-title":"Non-invasive ventilatory support in neonates: An evidence-based update","volume":"44","author":"Mahmoud","year":"2022","journal-title":"Paediatr. Respir. Rev."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1002\/ppul.23403","article-title":"Oscillation transmission and volume delivery during face mask-delivered HFOV in infants: Bench and in vivo study","volume":"51","author":"Costa","year":"2016","journal-title":"Pediatr. Pulmonol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1159\/000496462","article-title":"Mask versus Prongs for Nasal Continuous Positive Airway Pressure in Preterm Infants: A Systematic Review and Meta-Analysis","volume":"116","author":"King","year":"2019","journal-title":"Neonatology"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1002\/ppul.24120","article-title":"Nasal high-frequency oscillatory ventilation and CO2 removal: A randomized controlled crossover trial","volume":"53","author":"Bottino","year":"2018","journal-title":"Pediatr. Pulmonol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1080\/14767058.2018.1555810","article-title":"Noninvasive high-frequency oscillatory ventilation versus nasal continuous positive airway pressure in preterm infants with respiratory distress syndrome: A randomized controlled trial","volume":"33","author":"Malakian","year":"2020","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/S2213-2600(14)70194-8","article-title":"Neonatal ventilation trials need specific funding","volume":"2","author":"Taveira","year":"2014","journal-title":"Lancet Respir. Med."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"4499","DOI":"10.1007\/s00431-023-05128-4","article-title":"The effect of non-invasive high-frequency oscillatory ventilation on the duration of non-invasive respiratory support in late preterm and term infants with transient tachypnea of the newborn: A randomized controlled trial","volume":"182","author":"Baldan","year":"2023","journal-title":"Eur. J. Pediatr."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1002\/ppul.23824","article-title":"Nasal high-frequency oscillatory ventilation impairs heated humidification: A neonatal bench study","volume":"52","author":"Ullrich","year":"2017","journal-title":"Pediatr. Pulmonol."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Shi, Y., Muniraman, H., Biniwale, M., and Ramanathan, R. (2020). A Review on Non-invasive Respiratory Support for Management of Respiratory Distress in Extremely Preterm Infants. Front. Pediatr., 8.","DOI":"10.3389\/fped.2020.00270"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1007\/s12098-021-03755-z","article-title":"Noninvasive Respiratory Support in Neonates: A Review of Current Evidence and Practices","volume":"88","author":"Anne","year":"2021","journal-title":"Indian. J. Pediatr."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.resp.2018.02.003","article-title":"Nasal high-frequency oscillatory ventilation inhibits gastroesophageal reflux in the neonatal period","volume":"251","author":"Cantin","year":"2018","journal-title":"Respir. Physiol. Neurobiol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1007\/BF00262890","article-title":"Pressure-volume curves, static compliances and gas exchange in hyaline membrane disease during conventional mechanical and high-frequency ventilation","volume":"14","author":"Pfenninger","year":"1988","journal-title":"Intensive Care Med."},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Li, Y., Mo, Y., Yao, L., Wei, Q., Meng, D., Tan, W., and Pan, X. (2022). The long-term outcomes of preterm infants receiving non-invasive high-frequency oscillatory ventilation. Front. 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