{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:22:18Z","timestamp":1760145738848,"version":"build-2065373602"},"reference-count":24,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Autoimmune pancreatitis type 2 is a relatively novel entity with some still controversial issues. The current diagnostic algorithm relies on imaging studies and histology. Therapy includes corticosteroids with consequently low risk of relapse in the following year. However, the pathogenesis remains unclear, and data are insufficient for long-term prognosis. We have treated a 17-year-old boy whose autoimmune pancreatitis type 2 was revealed during surgery for a pre-existing biliary tract anomaly with concurrent protozoal infection. We discuss the co-occurrence of these conditions in terms of eventual pathogenesis correlation and combined effect on long-term prognosis.<\/jats:p>","DOI":"10.3390\/children11091075","type":"journal-article","created":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T03:45:21Z","timestamp":1725248721000},"page":"1075","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Autoimmune Pancreatitis Type 2, Biliary Cysts and Giardia lamblia"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3041-9090","authenticated-orcid":false,"given":"Tonka","family":"Bla\u017eevi\u0107","sequence":"first","affiliation":[{"name":"Department of Pediatrics, General Hospital Zadar, Bo\u017eePeri\u010di\u0107a5, 23000 Zadar, Croatia"},{"name":"Department of Pediatrics, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, Ki\u0161pati\u0107eva12, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirna Natalija","family":"Ani\u010di\u0107","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, Ki\u0161pati\u0107eva12, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanko","family":"\u0106avar","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, Ki\u0161pati\u0107eva12, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jurica","family":"Vukovi\u0107","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, Ki\u0161pati\u0107eva12, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.5009\/gnl210241","article-title":"Type 2 Autoimmune Pancreatitis: Consensus and Controversies","volume":"16","author":"Zen","year":"2022","journal-title":"Gut Liver"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/MPG.0000000000002028","article-title":"Recommendations for Diagnosis and Management of Autoimmune Pancreatitis in Childhood: Consensus from INSPPIRE","volume":"67","author":"Scheers","year":"2018","journal-title":"J. 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Gastroenterol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1097\/MPA.0000000000001307","article-title":"The Challenge of Autoimmune Pancreatitis: A Portrayal from the Pediatric Perspective","volume":"48","author":"Pagliari","year":"2019","journal-title":"Pancreas"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1046\/j.1365-2168.1998.00744.x","article-title":"Anomalous pancreaticobiliary junction without congenital choledochal cyst","volume":"85","author":"Sugiyama","year":"1998","journal-title":"Br. J. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0022-3468(82)80488-0","article-title":"Fictitious pancreatitis in choledochal cyst","volume":"17","author":"Stringel","year":"1982","journal-title":"J. Pediatr. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1038\/ajg.2017.85","article-title":"Autoimmune Pancreatitis in Children: Characteristic Features, Diagnosis, and Management","volume":"112","author":"Scheers","year":"2017","journal-title":"Am. J. Gastroenterol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.pan.2018.11.004","article-title":"Autoimmune pancreatitis in children: A single centre experience in diagnosis, management and long term follow up","volume":"19","author":"Lee","year":"2019","journal-title":"Pancreatology"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1002\/bjs.10798","article-title":"Meta-analysis of risk of developing malignancy in congenital choledochal malformation","volume":"105","author":"Hove","year":"2018","journal-title":"Br. J. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"14192","DOI":"10.18632\/oncotarget.13929","article-title":"Serum and tissue markers in hepatocellular carcinoma and cholangiocarcinoma: Clinical and prognostic implications","volume":"8","author":"Berretta","year":"2017","journal-title":"Oncotarget"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"e035","DOI":"10.1097\/PG9.0000000000000035","article-title":"Varied Presentations and Comorbidities in Pediatric Autoimmune Pancreatitis","volume":"2","author":"Suter","year":"2020","journal-title":"JPGN Rep."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"e326","DOI":"10.1097\/PG9.0000000000000326","article-title":"A Diagnostic Conundrum: A Case of Pediatric Autoimmune Pancreatitis","volume":"4","author":"Ravanbakhsh","year":"2023","journal-title":"JPGN Rep."},{"key":"ref_15","first-page":"3","article-title":"Autoimmune pancreatitis: What we know so far","volume":"6","author":"Masood","year":"2021","journal-title":"J. Gastroenterol. Hepatol. Found."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Sun, R., Xu, X., Zheng, Q., and Zhan, J. (2022). Therapeutic Endoscopic Retrograde Cholangiopancreatography for Pediatric Hepato-Pancreato-Biliary Diseases: A Systematic Review and Meta-Analysis. Front. Pediatr., 10.","DOI":"10.3389\/fped.2022.915085"},{"key":"ref_17","unstructured":"Meseeha, M., and Attia, M. (2024, July 21). Endoscopic Retrograde Cholangiopancreatography, StatPearls, Available online: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK493160\/."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1097\/MPG.0000000000003875","article-title":"Pediatric ERCP: Factors for Success and Complication\u2014A 17-Year, Multisite Experience","volume":"77","author":"Lorio","year":"2023","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1097\/MPG.0000000000003766","article-title":"Risk Factors for Post-ERCP Pancreatitis in Pediatric and Young Adult Patients","volume":"76","author":"Hassan","year":"2023","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.gie.2014.11.019","article-title":"The role of ERCP in benign diseases of the biliary tract","volume":"81","author":"Chathadi","year":"2015","journal-title":"Gastrointest. Endosc."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.parint.2019.04.013","article-title":"Another case of coincidental Giardia infection and pancreatic cancer","volume":"71","author":"Urban","year":"2019","journal-title":"Parasitol. Int."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1017\/S0031182000075053","article-title":"The effect of Giardia lamblia trophozoites on trypsin, chymotrypsin and amylase in vitro","volume":"106","author":"Seow","year":"1993","journal-title":"Parasitology"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.2169\/internalmedicine.56.8087","article-title":"Acute Acalculous Cholecystitis Caused by Giardia lamblia","volume":"56","author":"Araki","year":"2017","journal-title":"Intern. Med."},{"key":"ref_24","first-page":"165","article-title":"A case of giardiasis diagnosed by the presence of trophozite in intestinal washing during colonoscopy with liver abscess","volume":"57","author":"Kobayashi","year":"2015","journal-title":"Gastroenterol. Endosc."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/11\/9\/1075\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:46:35Z","timestamp":1760111195000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/11\/9\/1075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,1]]},"references-count":24,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2024,9]]}},"alternative-id":["children11091075"],"URL":"https:\/\/doi.org\/10.3390\/children11091075","relation":{},"ISSN":["2227-9067"],"issn-type":[{"type":"electronic","value":"2227-9067"}],"subject":[],"published":{"date-parts":[[2024,9,1]]}}}