{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T16:23:06Z","timestamp":1787934186083,"version":"build-2784847793"},"reference-count":22,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T00:00:00Z","timestamp":1726358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Isolated musculoskeletal infantile myofibroma is a rare tumor of pediatric age. The majority of cases are seen in children under two years old, but it can occur at any age as a painless enlarging mass that involves bone, skin, or soft tissue, typically accompanied by compression symptoms. Perineural involvement is extremely rare in myofibromas. Neurological impairment can occur during infancy but isolated nerve palsy, particularly in peripheral nerves within the upper extremity, is very uncommon. Neonatal radial nerve palsy is a rare entity caused by different conditions. Among these, we mention local tumors affecting peripheral nerves, such as myofibroma. There are few cases described in the literature, which mainly concern adult patients. The authors present a case of congenital isolated radial nerve palsy in a newborn with MF of the right elbow, which resulted in impairment of the wrist and finger extension. Following a six-month monitoring period, the patient underwent surgical treatment to restore function to his right wrist and hand. This involved excising the infiltrated radial nerve segment associated with palliative surgery. Despite the benignity of this lesion, severe nerve damage and perineural involvement may require surgical treatment with nerve resection and reconstruction.<\/jats:p>","DOI":"10.3390\/children11091126","type":"journal-article","created":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T04:14:07Z","timestamp":1726460047000},"page":"1126","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Isolated Radial Nerve Palsy in a Newborn Due to a Congenital Myofibroma: A Rare Case of Peripheral Nerve Injury"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8993-3488","authenticated-orcid":false,"given":"Serena","family":"Chiellino","sequence":"first","affiliation":[{"name":"Paediatric and Neonatologic Unit, Santo Stefano Hospital, 59100 Prato, Italy"},{"name":"Paediatric Pulmonary Unit, Meyer Children\u2019s Hospital IRCCS, 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viola","family":"Fortini","sequence":"additional","affiliation":[{"name":"Rehabilitation Department, Meyer Children\u2019s Hospital IRCCS, 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4939-4968","authenticated-orcid":false,"given":"Chiara","family":"Castellani","sequence":"additional","affiliation":[{"name":"Rehabilitation Department, Meyer Children\u2019s Hospital IRCCS, 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierluigi","family":"Vasarri","sequence":"additional","affiliation":[{"name":"Paediatric and Neonatologic Unit, Santo Stefano Hospital, 59100 Prato, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1590\/abd1806-4841.20175001","article-title":"Infantile Myofibromatosis","volume":"92","author":"Larralde","year":"2017","journal-title":"An. Bras. Dermatol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"794","DOI":"10.2174\/1874325001711010794","article-title":"Irreparable Radial Nerve Palsy Due to Delayed Diagnostic Management of a Giant Lipoma at the Proximal Forearm Resulting in a Triple Tendon Transfer Procedure: Case report and Brief Review of Literature","volume":"11","author":"Schmidt","year":"2017","journal-title":"Open Orthop. J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1097\/BPB.0b013e32832e4756","article-title":"A Rare Case of Infantile Myofibromatosis and Review of Literature","volume":"19","author":"Hausbrandt","year":"2010","journal-title":"J. Pediatr. Orthop. B."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.ajhg.2013.04.024","article-title":"Mutations in PDGFRB Cause Autosomal-Dominant Infantile Myofibromatosis","volume":"92","author":"Martignetti","year":"2013","journal-title":"Am. J. Hum. 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Orthop."},{"key":"ref_8","first-page":"21","article-title":"Paralysie N\u00e9onatal Unilat\u00e9rale Du Nerf Radial [Neonatal Unilateral Paralysis of the Radial Nerve]","volume":"13","author":"Benemmane","year":"2015","journal-title":"Pan. Afr. Med. J."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jhsa.2014.08.040","article-title":"Congenital Radial Nerve Palsy","volume":"40","author":"Song","year":"2015","journal-title":"J. Hand. Surg. Am."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e0284","DOI":"10.2106\/JBJS.CC.18.00284","article-title":"Spontaneous Radial Nerve Palsy due to an Unrecognized Myofibroma: A Case Report","volume":"9","author":"Hinchcliff","year":"2019","journal-title":"JBJS Case Connect."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1212\/01.wnl.0000342126.70570.33","article-title":"Bilateral Radial Nerve Palsy in a Newborn","volume":"72","author":"Lundy","year":"2009","journal-title":"Neurology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.clineuro.2016.11.001","article-title":"Anterior Interosseous Nerve and Posterior Interosseous Nerve Involvement in Neuralgic Amyotrophy","volume":"151","author":"Akane","year":"2016","journal-title":"Clin. Neurol. 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Study of a Series Suggesting a Continuous Spectrum of Infantile Myofibroblastic Lesions","volume":"18","author":"Mentzel","year":"1994","journal-title":"Am. J. Surg. Pathol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1148\/rg.2016150191","article-title":"Pediatric Fibroblastic and Myofibroblastic Tumors: A Pictorial Review","volume":"36","author":"Sargar","year":"2016","journal-title":"Radiographics"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"e204","DOI":"10.1097\/GOX.0000000000000153","article-title":"Myofibroma in the Palm Presenting with Median Nerve Compression Symptoms","volume":"2","author":"Sarkozy","year":"2014","journal-title":"Plast. Reconstr. Surg. Glob. Open."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/11\/9\/1126\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:56:49Z","timestamp":1760111809000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/11\/9\/1126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,15]]},"references-count":22,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2024,9]]}},"alternative-id":["children11091126"],"URL":"https:\/\/doi.org\/10.3390\/children11091126","relation":{},"ISSN":["2227-9067"],"issn-type":[{"value":"2227-9067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,15]]}}}