{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T22:06:00Z","timestamp":1789077960742,"version":"build-2803163510"},"reference-count":37,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:00:00Z","timestamp":1728259200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background: Myelomeningocele (MMC) is a congenital malformation affecting the central nervous system, categorized as a neural tube defect (NTDs). In untreated cases, the mortality rate within the first six months of life ranges from 35% to 70%. Globally, its incidence is estimated 0.8 to 1 per 1000 live births, and rates are higher in Asia and lower socioeconomic groups. This disease imposes a significant treatment cost and burden due to life-long disabilities. In less developed or developing countries, delays in diagnosis can lead to complications such as infection and rupture. Although rupture is a rare complication in MMC, there are limited studies that have reported it. This study aims to discuss the perioperative management and potential complications of ruptured MMC. Method: This study presents four cases of ruptured MMC that were referred from private hospitals and managed by Hasan Sadikin General Hospital in West Java, Indonesia. Each patiens underwent a clinical assessment and diagnostic evaluation upon arrival, followed by perioperative theraphy and management of any complications that emerged during treatment. Result: In three of the four cases, the children were over 24 h old when they were admitted to the hospital. Three cases were located in the lumbosacral region while one case was located in the thoracic region. Upon arrival, the clinical presentations we observed included microcephaly, small for gestational age (SGA) and congenital talipes equionavrus (CTEV). And we found several complications included wound dehisence, respiratiory failure, hydrocephalus, leg weakness, menigitis and sepsis after surgery. Conclusions: Perioperative management is highlighted as vital, necessitating a multidisciplinary approach and precise surgical techniques to mitigate severe complications.<\/jats:p>","DOI":"10.3390\/children11101219","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T06:23:18Z","timestamp":1728282198000},"page":"1219","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Meningomyelocele Perioperative Management in Neonatal: Case Series"],"prefix":"10.3390","volume":"11","author":[{"given":"Filla Reviyani","family":"Suryaningrat","sequence":"first","affiliation":[{"name":"Department of Child Health, Faculty of Medicine, Universitas Padjajaran, Dr. Hasan Sadikin General Hospital, Bandung 40161, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sindy","family":"Irenewati","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universitas Diponegoro, Semarang 50244, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5208-9233","authenticated-orcid":false,"given":"Mirna","family":"Sobana","sequence":"additional","affiliation":[{"name":"Department of Neurosugery, Faculty of Medicine, Universitas Padjajaran, Dr. Hasan Sadikin General Hospital, Bandung 40161, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiva Aprilia","family":"Kadi","sequence":"additional","affiliation":[{"name":"Department of Child Health, Faculty of Medicine, Universitas Padjajaran, Dr. Hasan Sadikin General Hospital, Bandung 40161, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aris","family":"Primadi","sequence":"additional","affiliation":[{"name":"Department of Child Health, Faculty of Medicine, Universitas Padjajaran, Dr. Hasan Sadikin General Hospital, Bandung 40161, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetty","family":"Yuniati","sequence":"additional","affiliation":[{"name":"Department of Child Health, Faculty of Medicine, Universitas Padjajaran, Dr. Hasan Sadikin General Hospital, Bandung 40161, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,7]]},"reference":[{"key":"ref_1","first-page":"1","article-title":"Myelomeningocele-A literature review","volume":"19","author":"Jimmy","year":"2020","journal-title":"Interdiscip. 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