{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T15:09:02Z","timestamp":1783523342305,"version":"3.55.0"},"reference-count":22,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T00:00:00Z","timestamp":1732579200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Introduction: Proper bladder drainage is crucial. Children with bladder dysfunction may require alternative methods like clean intermittent catheterisation (CIC). However, CIC can be challenging for individuals with impairments. The Mitrofanoff procedure provides a solution by connecting the appendix to the bladder and creating a stoma on the skin, allowing for continent catheterisation. Minimally invasive techniques, including robotics, have been adopted recently. The aim of this study is to review the existing literature on robotic Mitrofanoff procedures. Materials and Methods: A systematic review on paediatric robotic Mitrofanoff procedures on the PubMed, Cochrane, and Scopus databases was conducted according to the PRISMA Statement. Critical appraisals of the included studies were performed with the Newcastle Ottawa Scale. Results: Six studies were included about the robotic Mitrofanoff procedure. Sex was reported in 50% of the studies. Ages were within the twelve-year age limit, as per the inclusion criteria. The mean operative time was 499.3 (\u00b1171.1) min. Four of the six studies reported a length of stay with a median of 6 days (\u00b14; range 1.8\u201323). The incidence of complications was in line with established benchmarks. Only one study compared the Mitrofanoff procedure to open surgery, finding similar outcomes but longer operating times. Port placement and surgical strategy was described. Conclusions: Robotics can offer potential advantages for the Mitrofanoff procedure, despite its application still being in its early stages. This study emphasises the potential safety and efficacy of the robotic approach and promotes the need for further prospective high-quality studies.<\/jats:p>","DOI":"10.3390\/children11121442","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T04:20:12Z","timestamp":1732681212000},"page":"1442","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Mitrofanoff Appendicovesicostomy in Robotic Paediatric Surgery\u2014A Systematic Review"],"prefix":"10.3390","volume":"11","author":[{"given":"Diana","family":"Ronconi Di Giuseppe","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, Portsmouth Hospitals University NHS Trust, Portsmouth PO6 3LY, UK"},{"name":"Department of Surgery, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry","family":"Claxton","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3118-0641","authenticated-orcid":false,"given":"Rauand","family":"Duhoky","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Portsmouth Hospitals University NHS Trust, Portsmouth PO6 3LY, UK"},{"name":"Department of General Surgery, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK"},{"name":"School of Computing, Faculty of Technology, University of Portsmouth, Portsmouth PO1 2UP, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6667-9202","authenticated-orcid":false,"given":"Guglielmo Niccol\u00f2","family":"Piozzi","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Portsmouth Hospitals University NHS Trust, Portsmouth PO6 3LY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3031-4495","authenticated-orcid":false,"given":"Jim S.","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Portsmouth Hospitals University NHS Trust, Portsmouth PO6 3LY, UK"},{"name":"Faculty of Science and Health, University of Portsmouth, Portsmouth PO1 2UP, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Duhoky, R., Claxton, H., Piozzi, G.N., and Khan, J.S. (2024). Robotic Approach to Paediatric Gastrointestinal Diseases: A Systematic Review. Children, 11.","DOI":"10.3390\/children11030273"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"112.e1","DOI":"10.1016\/j.jpurol.2021.12.018","article-title":"Pediatric laparoscopic mitrofanoff procedure-preliminary results of a simplified rechnique","volume":"18","author":"Gander","year":"2022","journal-title":"J. Pediatr. Urol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.jpurol.2010.01.015","article-title":"Educational article: The Mitrofanoff procedure","volume":"6","author":"Farrugia","year":"2010","journal-title":"J. Pediatr. Urol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1007\/s11701-023-01559-1","article-title":"Robotic-assisted pyeloplasty in children: A systematic review of the literature","volume":"17","author":"Esposito","year":"2023","journal-title":"J. Robot. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1089\/end.2011.0031","article-title":"Robot-assisted bladder neck reconstruction, bladder neck sling, and appendicovesicostomy in children: Description of technique and initial results","volume":"25","author":"Bagrodia","year":"2011","journal-title":"J. Endourol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1016\/S0022-5347(05)66213-1","article-title":"The Mitrofanoff procedure: 20 years later","volume":"165","author":"Liard","year":"2001","journal-title":"J. Urol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1016\/j.juro.2009.06.055","article-title":"Robotic assisted laparoscopic Mitrofanoff appendicovesicostomy: Preliminary experience in a pediatric population","volume":"182","author":"Nguyen","year":"2009","journal-title":"J. Urol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.eururo.2013.05.007","article-title":"Robot-assisted laparoscopic Mitrofanoff appendicovesicostomy technique and outcomes of extravesical and intravesical approaches","volume":"64","author":"Famakinwa","year":"2013","journal-title":"Eur. Urol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/bco2.7","article-title":"Robot-assisted laparoscopic augmentation ileocystoplasty and Mitrofanoff appendicovesicostomy in children: Step-by-step and modifications to UChicago technique","volume":"1","author":"Adamic","year":"2020","journal-title":"BJUI Compass"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1097\/01.ju.0000116066.72132.9a","article-title":"Laparoscopic appendicovesicostomy (Mitrofanoff procedure) in a child using the da Vinci robotic system","volume":"171","author":"Pedraza","year":"2004","journal-title":"J. Urol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.juro.2010.11.050","article-title":"Continence Outcomes in Patients Undergoing Robotic Assisted Laparoscopic Mitrofanoff Appendicovesicostomy","volume":"185","author":"Wille","year":"2010","journal-title":"J. Urol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1111\/j.1464-410X.2010.09706.x","article-title":"Paediatric robotic-assisted laparoscopic augmentation ileocystoplasty and Mitrofanoff appendicovesicostomy (RALIMA): Feasibility of and initial experience with the University of Chicago technique","volume":"107","author":"Gundeti","year":"2010","journal-title":"BJU Int."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1016\/S0022-5347(05)67599-4","article-title":"Appendicovesicostomy: The mitrofanoff procedure-a 15-year perspective","volume":"163","author":"Harris","year":"2000","journal-title":"J. Urol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0094-0143(05)70421-3","article-title":"The Mitrofanoff principle in continent urinary reconstruction","volume":"24","author":"Kaefer","year":"1997","journal-title":"Urol. Clin. North. Am."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1016\/S0022-5347(06)00610-0","article-title":"Continent catheterizable channels and the timing of their complications","volume":"176","author":"Thomas","year":"2006","journal-title":"J. Urol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1016\/j.juro.2011.02.601","article-title":"Long-term followup and time to event outcome analysis of continent catheterizable channels","volume":"185","author":"Leslie","year":"2011","journal-title":"J. Urol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1001\/jama.2011.743","article-title":"Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome","volume":"305","author":"Bonadona","year":"2011","journal-title":"JAMA"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/S0090-4295(96)00448-7","article-title":"Laparoscopic creation of a catheterizable cutaneous ureterovesicostomy","volume":"49","author":"Strand","year":"1997","journal-title":"Urology"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1097\/01.ju.0000101696.20531.2b","article-title":"Laparoscopic assisted reconstructive surgery: A 7-year experience","volume":"171","author":"Chung","year":"2004","journal-title":"J. Urol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.eucr.2018.08.009","article-title":"Cecal volvulus with gangrene following Mitrofanoff procedure","volume":"21","author":"Chavez","year":"2018","journal-title":"Urol. Case Rep."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Abdulfattah, S., Eftekharzadeh, S., Ai, E., Aghababian, A., Overland, M., Mittal, S., Srinivasan, A.K., and Shukla, A.R. (2024). Is robot-assisted appendicovesicostomy equivalent to the current gold standard open procedure? A comparative analysis. J. Pediatr. Urol.","DOI":"10.1016\/j.jpurol.2024.09.027"}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/11\/12\/1442\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:40:05Z","timestamp":1760114405000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/11\/12\/1442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,26]]},"references-count":22,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["children11121442"],"URL":"https:\/\/doi.org\/10.3390\/children11121442","relation":{},"ISSN":["2227-9067"],"issn-type":[{"value":"2227-9067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,26]]}}}