{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T23:36:20Z","timestamp":1768260980422,"version":"3.49.0"},"reference-count":19,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T00:00:00Z","timestamp":1732752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Align Technology, Ltd., manufacturer of the Itero Element 5D scanner"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Objectives: The present prospective study aimed to compare near-infrared light reflection (NIRI) and bitewing radiographs (BWR) images to detect proximal caries in primary teeth. Methods: 71 children underwent routine BWR, and scans were performed using an intra-oral scanner (iTero Element 5D, Align Technology, Tempe, AZ, USA), including a near-infrared light source (850 nm) and sensor. Five specialist pediatric dentists examined the NIRI and BWR images. Results: The average participant age was 7.8 years. A total of 1004 proximal surfaces of primary molars and canines were examined, 209 carious lesions were detected on BWR, and 227 on NIRI. Comparison between all carious lesions detected on BWR and NIRI: Sensitivity (53.6%); Specificity (85.5%); Positive Predictive Value (PPV) (49.3%); Negative Predictive Value (NPV) (87.5%). Comparison between carious lesions involving the DEJ detected on BWR and at any level in NIRI: Sensitivity (61%); Specificity (83.4%), PPV (36.6%); NPV (93.2%). Comparison between enamel-only carious lesions detected on BWR and all lesions detected using NIRI: Sensitivity (44.8%); Specificity (85.5%); PPV (20.7%); NPV (94.8%). Conclusions: No additional diagnostic information can be gleaned from BWR if initial caries lesions in the enamel are not detected by clinical examination or in images from a NIRI scanner, making BWR unnecessary.<\/jats:p>","DOI":"10.3390\/children11121455","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T07:28:01Z","timestamp":1732778881000},"page":"1455","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparing Images from Near-Infrared Light Reflection and Bitewing Radiography to Detect Proximal Caries in Primary Teeth"],"prefix":"10.3390","volume":"11","author":[{"given":"Aviv","family":"Shmueli","sequence":"first","affiliation":[{"name":"Department of Pediatric Dentistry, Faculty of Dental Medicine, Hebrew University, Hadassah Medical Center, P.O. Box 12272, Jerusalem 91120, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avia","family":"Fux-Noy","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Faculty of Dental Medicine, Hebrew University, Hadassah Medical Center, P.O. Box 12272, Jerusalem 91120, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esti","family":"Davidovich","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Faculty of Dental Medicine, Hebrew University, Hadassah Medical Center, P.O. Box 12272, Jerusalem 91120, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Ram","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Faculty of Dental Medicine, Hebrew University, Hadassah Medical Center, P.O. Box 12272, Jerusalem 91120, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4118-2501","authenticated-orcid":false,"given":"Moti","family":"Moskovitz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Faculty of Dental Medicine, Hebrew University, Hadassah Medical Center, P.O. Box 12272, Jerusalem 91120, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.17796\/1053-4628-41.5.358","article-title":"Caries Progression Rate in Primary Teeth: A Retrospective Study","volume":"41","author":"Tickotsky","year":"2017","journal-title":"J. Clin. Pediatr. Dent."},{"key":"ref_2","first-page":"493","article-title":"Comparison of proximal caries detection in primary teeth between laser fluorescence and bitewing radiography","volume":"27","author":"Virajsilp","year":"2005","journal-title":"Pediatr. Dent."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1111\/ipd.12783","article-title":"The global prevalence of early childhood caries: A systematic review with meta-analysis using the WHO diagnostic criteria","volume":"31","author":"Uribe","year":"2021","journal-title":"Int. J. Paediatr. Dent."},{"key":"ref_4","first-page":"371","article-title":"An in vivo comparison of radiographic and clinical examination with separation for assessment of approximal caries in primary teeth","volume":"15","author":"Coutinho","year":"2014","journal-title":"Eur. J. Paediatr. Dent."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1177\/00220345211042795","article-title":"Enamel Caries Detection and Diagnosis: An Analysis of Systematic Reviews","volume":"101","author":"Walsh","year":"2022","journal-title":"J. Dent. Res."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/ipd.12478","article-title":"In vivo validity of proximal caries detection in primary teeth, with histological validation","volume":"29","author":"Subka","year":"2019","journal-title":"Int. J. Paediatr. Dent."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.adaj.2023.06.015","article-title":"Patient shielding during dentomaxillofacial radiography: Recommendations from the American Academy of Oral and Maxillofacial Radiology","volume":"154","author":"Benavides","year":"2023","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Serban, C., Lungeanu, D., Bota, S.D., Cotca, C.C., Negrutiu, M.L., Duma, V.F., Sinescu, C., and Craciunescu, E.L. (2022). Emerging Technologies for Dentin Caries Detection-A Systematic Review and Meta-Analysis. J. Clin. Med., 11.","DOI":"10.3390\/jcm11030674"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"6069","DOI":"10.1007\/s00784-021-04024-1","article-title":"Systematic review and meta-analysis of diagnostic studies of proximal surface caries","volume":"25","author":"Kapor","year":"2021","journal-title":"Clin. Oral. Investig."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s40368-020-00538-6","article-title":"In vivo correlation of near-infrared transillumination and visual inspection with bitewing radiography for the detection of interproximal caries in permanent and primary teeth","volume":"21","author":"Vandenbulcke","year":"2020","journal-title":"Eur. Arch. Paediatr. Dent."},{"key":"ref_11","first-page":"74","article-title":"Evaluation of detecting proximal caries in posterior teeth via visual inspection, digital bitewing radiography and near-infrared light transillumination","volume":"32","author":"Schaefer","year":"2019","journal-title":"Am. J. Dent."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.adaj.2014.11.018","article-title":"The American Dental Association Caries Classification System for clinical practice: A report of the American Dental Association Council on Scientific Affairs","volume":"146","author":"Young","year":"2015","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Chow, S.C., Shao, J., Wang, H., and Lokhnygina, Y. (2017). Sample Size Calculations in Clinical Research, Chapman and Hall\/CRC.","DOI":"10.1201\/9781315183084"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1016\/j.jds.2023.05.015","article-title":"Parents\u2019 perspective towards dental radiography for children","volume":"18","author":"Birant","year":"2023","journal-title":"J. Dent. Sci."},{"key":"ref_15","unstructured":"(2018). Prescribing Dental Radiographs for Infants, Children, Adolescents, and Individuals with Special Health Care Needs. Pediatr. Dent., 40, 213\u2013215."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s40368-019-00493-x","article-title":"Best clinical practice guidance for prescribing dental radiographs in children and adolescents: An EAPD policy document","volume":"21","author":"Anttonen","year":"2020","journal-title":"Eur. Arch. Paediatr. Dent."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s40368-015-0208-6","article-title":"Detection and monitoring of early caries lesions: A review","volume":"17","author":"Pretty","year":"2016","journal-title":"Eur. Arch. Paediatr. Dent."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s40368-015-0218-4","article-title":"Best clinical practice guidance for management of early caries lesions in children and young adults: An EAPD policy document","volume":"17","author":"Ekstrand","year":"2016","journal-title":"Eur. Arch. Paediatr. Dent."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"103861","DOI":"10.1016\/j.jdent.2021.103861","article-title":"Reflected near-infrared light versus bite-wing radiography for the detection of proximal caries: A multicenter prospective clinical study conducted in private practices","volume":"116","author":"Metzger","year":"2022","journal-title":"J. Dent."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/11\/12\/1455\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:41:41Z","timestamp":1760114501000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/11\/12\/1455"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,28]]},"references-count":19,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["children11121455"],"URL":"https:\/\/doi.org\/10.3390\/children11121455","relation":{},"ISSN":["2227-9067"],"issn-type":[{"value":"2227-9067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,28]]}}}