{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T07:48:00Z","timestamp":1790063280327,"version":"4.0.1"},"reference-count":26,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background and aim: Cerebral palsy (CP) is a nonprogressive neurological disorder characterized by permanent developmental disorders of movement and posture. One of the most common goals of rehabilitation is the treatment of gait disorders. Ataxic gait disorder tends to worsen in the adolescent period. Research indicates a positive therapeutic effect of the combined application of conventional rehabilitation, robotic neurorehabilitation (RNR) and virtual reality, but there is no consensus on the length of treatment and frequency of application. The aim of this case report was to contribute to the definition of the RNR protocol for the treatment of ataxic gait disorder in adolescents with CP. Case report: In a female child with an ataxic form of CP who was on regular conventional kinesitherapy in the age period between 13 to 15 years, robotic-assisted gait training (RAGT) was applied for the treatment of gait disorders. The rehabilitation protocol lasted 10 weeks, 5 times a week, and included individual, conventional kinesitherapy for 30 min and RAGT for 30 min. Combined RNR treatment was conducted once a year in the period between July and September. The results of the therapeutic evaluation revealed that the functional motor level remained unchanged, while the improved functional motor status for the category of standing and gait was maintained during treatment between the patient\u2019s 13 and 15 years age. In their 15th year, independent gait over a shorter distance (14 m) was achieved, as well as a normal gait frequency (83 steps\/minute), with a desirable duration of the left leg support phase of 65% and 70% for the right leg support phase. Conclusions: The results of our research indicate that the application of conventional kinesitherapy and RAGT, over the period of 10 weeks a year, can have a positive effect on improving the postural and locomotor functions of ataxic gait in adolescents with CP.<\/jats:p>","DOI":"10.3390\/children12020190","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T04:47:31Z","timestamp":1738817251000},"page":"190","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Influence of Robotic Neurorehabilitation in Cerebral Palsy on Motor Function and Gait"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6041-2910","authenticated-orcid":false,"given":"Hristina","family":"Colovic","sequence":"first","affiliation":[{"name":"Department for Physical Medicine and Rehabilitation, Faculty of Medicine, University of Ni\u0161, 18000 Ni\u0161, Serbia"},{"name":"Clinic for Physical Medicine and Rehabilitation, University Clinical Center Ni\u0161, 18000 Ni\u0161, Serbia"},{"name":"Polyclinic Neuromedic Group Plus, 18000 Ni\u0161, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0609-9916","authenticated-orcid":false,"given":"Dejan","family":"Nikolic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"},{"name":"Department of Physical Medicine and Rehabilitation, University Children\u2019s Hospital, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dragan","family":"Zlatanovic","sequence":"additional","affiliation":[{"name":"Department for Physical Medicine and Rehabilitation, Faculty of Medicine, University of Ni\u0161, 18000 Ni\u0161, Serbia"},{"name":"Clinic for Physical Medicine and Rehabilitation, University Clinical Center Ni\u0161, 18000 Ni\u0161, Serbia"},{"name":"Polyclinic Neuromedic Group Plus, 18000 Ni\u0161, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vesna","family":"Zivkovic","sequence":"additional","affiliation":[{"name":"Department for Physical Medicine and Rehabilitation, Faculty of Medicine, University of Ni\u0161, 18000 Ni\u0161, Serbia"},{"name":"Clinic for Physical Medicine and Rehabilitation, University Clinical Center Ni\u0161, 18000 Ni\u0161, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Stankovic","sequence":"additional","affiliation":[{"name":"Department for Physical Medicine and Rehabilitation, Faculty of Medicine, University of Ni\u0161, 18000 Ni\u0161, Serbia"},{"name":"Clinic for Physical Medicine and Rehabilitation, University Clinical Center Ni\u0161, 18000 Ni\u0161, Serbia"},{"name":"Polyclinic Neuromedic Group Plus, 18000 Ni\u0161, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasna","family":"Stojkovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"},{"name":"Department of Physical Medicine and Rehabilitation, University Children\u2019s Hospital, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasa","family":"Mujovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"},{"name":"Center for Physical Medicine and Rehabilitation, University Clinical Center of Serbia, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sindi","family":"Mitrovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"},{"name":"Clinic for Rehabilitation \u201cDr Miroslav Zotovic\u201d, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nevena","family":"Krstic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"},{"name":"Center for Physical Medicine and Rehabilitation, University Clinical Center of Serbia, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6454-390X","authenticated-orcid":false,"given":"Natasa","family":"Radosavljevic","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, State University of Novi Pazar, 36300 Novi Pazar, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"ref_1","first-page":"8","article-title":"A report: The definition and classification of cerebral palsy April 2006","volume":"109","author":"Rosenbaum","year":"2007","journal-title":"Dev. Med. Child Neurol. Suppl."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/apa.14147","article-title":"The panorama of cerebral palsy in Sweden part XII shows that patterns changed in the birth years 2007\u20132010","volume":"107","author":"Himmelmann","year":"2018","journal-title":"Acta Paediatr."},{"key":"ref_3","unstructured":"Kinsner-Ovaskainen, A., Lanzoni, M., Delobel-Ayoub, M., Ehlinger, V., Arnaud, C., and Martin, S. (2017). Surveillance of Cerebral Palsy in Europe: Development of the JRC-SCPE Central Database and Public Health Indicators, Publications Office of the European Union. Available online: https:\/\/publications.jrc.ec.europa.eu\/repository\/handle\/JRC109418."},{"key":"ref_4","first-page":"691","article-title":"Recommendations for the rehabilitation of children with cerebral palsy","volume":"52","author":"Castelli","year":"2016","journal-title":"Eur. J. Phys. Rehabil. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/09638288.2019.1623852","article-title":"Quality of life in children and adolescents with cerebral palsy: A systematic review with meta-analysis","volume":"43","author":"Makris","year":"2021","journal-title":"Disabil. Rehabil."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.gaitpost.2018.05.004","article-title":"Gait pathology subtypes are not associated with self-reported fall frequency in children with cerebral palsy","volume":"63","author":"Boyer","year":"2018","journal-title":"Gait Posture"},{"key":"ref_7","first-page":"311","article-title":"Gait activities beyond gait training: Priorities in everyday life for parents and adolescents in pediatric neurorehabilitation","volume":"15","author":"Graser","year":"2022","journal-title":"J. Pediatr. Rehabil. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s10072-023-07012-3","article-title":"New approaches to recovery after stroke","volume":"45","year":"2024","journal-title":"Neurol. Sci."},{"key":"ref_9","first-page":"49","article-title":"The Role of Robotic Rehabilitation in Children with Neurodevelopmental Disorders","volume":"33","author":"Castelli","year":"2021","journal-title":"Psychiatr. Danub."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1177\/02692155221087084","article-title":"Is robotic gait training effective for individuals with cerebral palsy? A systematic review and meta-analysis of randomized controlled trials","volume":"36","author":"Conner","year":"2022","journal-title":"Clin. Rehabil."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Gonzalez, A., Garcia, L., Kilby, J., and McNair, P. (2021). Robotic devices for paediatric rehabilitation: A review of design features. Biomed. Eng. Online, 20.","DOI":"10.1186\/s12938-021-00920-5"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Colovic, H., Zlatanovic, D., Zivkovic, V., Jankovic, M., Radosavljevic, N., Ducic, S., Ducic, J., Stojkovic, J., Jovanovic, K., and Nikolic, D. (2024). A Review of Current Perspectives on Motoric Insufficiency Rehabilitation following Pediatric Stroke. Healthcare, 12.","DOI":"10.3390\/healthcare12020149"},{"key":"ref_13","unstructured":"(2025, January 09). LEXO\u00ae. Available online: https:\/\/tyromotion.com\/en\/lexo\/."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1111\/j.1469-8749.2008.03089.x","article-title":"Content validity of the expanded and revised Gross Motor Function Classification System","volume":"50","author":"Palisano","year":"2008","journal-title":"Dev. Med. Child Neurol."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Russell, D.J., Wright, M., Rosenbaum, P.J., and Avery, L.M. (2021). Gross Motor Function Measure (GMFM-66 & GMFM-88) Users Manual, Mac Keith Press. [3rd ed.].","DOI":"10.1097\/PEP.0000000000000858"},{"key":"ref_16","unstructured":"(2025, January 09). PABLO\u00ae. Available online: https:\/\/tyromotion.com\/en\/products\/pablo\/."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.bjpt.2019.04.005","article-title":"Combining balance-training interventions with other active interventions may enhance effects on postural control in children and adolescents with cerebral palsy: A systematic review and meta-analysis","volume":"24","author":"Starling","year":"2020","journal-title":"Braz. J. Phys. Ther."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3109\/01942638.2010.500581","article-title":"A systematic review of common physiotherapy interventions in school-aged children with cerebral palsy","volume":"30","author":"Martin","year":"2010","journal-title":"Phys. Occup. Ther. Pediatr."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/09638288.2013.775359","article-title":"Gait function and decline in adults with cerebral palsy: A systematic review","volume":"36","author":"Morgan","year":"2014","journal-title":"Disabil. Rehabil."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"De Luca, R., Bonanno, M., Settimo, C., Muratore, R., and Calabr\u00f2, R.S. (2022). Improvement of Gait after Robotic-Assisted Training in Children with Cerebral Palsy: Are We Heading in the Right Direction?. Med. Sci., 10.","DOI":"10.3390\/medsci10040059"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/0888439002250442","article-title":"Locomotor Training in Neurorehabilitation: Emerging Rehabilitation concepts","volume":"17","author":"Barbeau","year":"2003","journal-title":"Neurorehabil. Neural. Repair."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.gaitpost.2017.11.007","article-title":"Effect of robotic-assisted gait rehabilitation on dynamic equilibrium control in the gait of children with cerebral palsy","volume":"60","author":"Wallard","year":"2018","journal-title":"Gait Posture"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"671","DOI":"10.3233\/THC-160668","article-title":"Effects of dose and duration of Robot-assisted gait training on gait ability of children affected by cerebral palsy","volume":"25","author":"Peri","year":"2017","journal-title":"Technol. Health Care"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.gaitpost.2019.03.017","article-title":"Effects of robotic rehabilitation on gait and balance in pediatric patients with hemiparetic cerebral palsy","volume":"70","author":"Tekin","year":"2019","journal-title":"Gait Posture"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"B\u0142a\u017ckiewicz, M., and Hadamus, A. (2024). Assessing the Efficacy of Lokomat Training in Pediatric Physiotherapy for Cerebral Palsy: A Progress Evaluation. J. Clin. Med., 13.","DOI":"10.3390\/jcm13216417"},{"key":"ref_26","unstructured":"Royal College of Paediatrics and Child Health (2017). Stroke in Childhood: Clinical Guideline for Diagnosis, Management and Rehabilitation, RCP."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/12\/2\/190\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:27:47Z","timestamp":1760027267000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/12\/2\/190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,6]]},"references-count":26,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["children12020190"],"URL":"https:\/\/doi.org\/10.3390\/children12020190","relation":{},"ISSN":["2227-9067"],"issn-type":[{"value":"2227-9067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,6]]}}}