{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:24:07Z","timestamp":1793139847118,"version":"4.5.0"},"reference-count":24,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background\/Objectives: Vitamin D deficiency in children has been linked to various metabolic disturbances, including dyslipidemia, which contributes to cardiovascular risk. This study aims to investigate the relationship between vitamin D levels and lipid profiles in children. Methods: A cohort of 332 children with either normal vitamin D or diagnosed vitamin D deficiency was recruited. Serum vitamin D levels were measured, and lipid profiles, including total cholesterol, low-density lipoproteins (LDLs), high-density lipoproteins (HDLs), and triacylglycerols (TAGs), were assessed. The data were analyzed using statistical methods. Results: This study found that children with higher serum vitamin D concentrations had significantly lower TAG (p = 0.033) and very-low-density lipoprotein (VLDL) (p = 0.038) levels and higher HDL levels (p = 0.042), indicating a more favorable lipid profile compared to those with lower vitamin D levels. Conclusions: This study demonstrates that vitamin D deficiency can be associated with dyslipidemia in children. These findings suggest that vitamin D supplementation may be an effective strategy for managing dyslipidemia and reducing cardiovascular risk in pediatric populations. Further research is needed to determine the long-term effects and optimal dosing of vitamin D in this context.<\/jats:p>","DOI":"10.3390\/children12050546","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T08:08:41Z","timestamp":1745482121000},"page":"546","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Lipid Profile Alterations in Pediatric Patients with Vitamin D Deficiency"],"prefix":"10.3390","volume":"12","author":[{"given":"Jasmina","family":"Katani\u0107","sequence":"first","affiliation":[{"name":"Institute for Children and Youth Health Care of Vojvodina, 21000 Novi Sad, Serbia"},{"name":"Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8726-1953","authenticated-orcid":false,"given":"Dejan","family":"Dobrijevi\u0107","sequence":"additional","affiliation":[{"name":"Institute for Children and Youth Health Care of Vojvodina, 21000 Novi Sad, Serbia"},{"name":"Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents, and National Heart, Lung, and Blood Institute (2011). 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Clin. Nutr."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1093\/ajcn\/nqz340","article-title":"Effect of vitamin D3 supplementation on vascular and metabolic health of vitamin D-deficient overweight and obese children: A randomized clinical trial","volume":"111","author":"Rajakumar","year":"2020","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_6","unstructured":"Scientific Advisory Committee on Nutrition (2025, January 17). Vitamin D and Health, Available online: https:\/\/www.gov.uk\/government\/publications\/sacn-vitamin-d-and-health-report."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1016\/j.advnut.2023.08.012","article-title":"The Effect of Vitamin D Supplementation on Lipid Profiles: An Umbrella Review of Meta-Analyses","volume":"14","author":"Radkhah","year":"2023","journal-title":"Adv. Nutr."},{"key":"ref_8","unstructured":"(2025, January 17). Clinical Practice Guidelines. Vitamin D Deficiency. 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