{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:28:13Z","timestamp":1792092493775,"version":"4.4.0"},"reference-count":94,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Indoor air pollution (IAP) has emerged as a critical yet underrecognized threat to public health, particularly in non-industrial environments such as homes, schools, and healthcare facilities. As individuals spend approximately 90% of their time indoors, exposure to indoor pollutants\u2014such as particulate matter, volatile organic compounds (VOCs), polycyclic aromatic hydrocarbons (PAHs), and microbial contaminants\u2014can lead to significant health risks. These risks disproportionately affect vulnerable populations, including children, the elderly, and individuals with pre-existing conditions. The effects range from mild respiratory symptoms to severe outcomes like asthma, cardiovascular diseases, and cancer. This review investigates the sources, typologies, and health effects of indoor air pollutants, with a focus on their implications for maternal and child health. In particular, children\u2019s developing systems and higher metabolic intake make them more susceptible to airborne toxins. The study also explores the legal and regulatory frameworks surrounding indoor air quality (IAQ), emphasizing how increased awareness and scientific evidence are expanding the scope of medical\u2013legal responsibility. Legal liabilities may arise for property owners, designers, or manufacturers when poor IAQ leads to demonstrable health outcomes. Despite growing concern, there remains a significant research gap concerning the long-term health effects of chronic low-level exposure in residential settings and the efficacy of mitigation strategies. The evolution of smart building technologies and green construction practices offers promising avenues to improve IAQ while maintaining energy efficiency. However, standards and regulations often lag behind scientific findings, highlighting the need for updated, enforceable policies that prioritize human health. This work underscores the urgency of a multidisciplinary and preventive approach to IAQ, integrating public health, environmental engineering, and legal perspectives. Future research should focus on real-time IAQ monitoring, targeted interventions for high-risk populations, and the development of comprehensive legal frameworks to ensure accountability and promote healthier indoor environments.<\/jats:p>","DOI":"10.3390\/children12101287","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T10:39:42Z","timestamp":1758710382000},"page":"1287","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Medical\u2013Legal Liability and Indoor Air Pollution in Non-Industrial Environments and Perspectives for Maternal and Child Health"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0917-7809","authenticated-orcid":false,"given":"Ginevra","family":"Malta","sequence":"first","affiliation":[{"name":"Department of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90129 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0508-6523","authenticated-orcid":false,"given":"Angelo","family":"Montana","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences and Public Health, University Politecnica delle Marche, 60126 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9964-0184","authenticated-orcid":false,"given":"Antonina","family":"Argo","sequence":"additional","affiliation":[{"name":"Department of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90129 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1101-0864","authenticated-orcid":false,"given":"Stefania","family":"Zerbo","sequence":"additional","affiliation":[{"name":"Department of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90129 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4786-8435","authenticated-orcid":false,"given":"Fulvio","family":"Plescia","sequence":"additional","affiliation":[{"name":"Department of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90129 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7070-209X","authenticated-orcid":false,"given":"Emanuele","family":"Cannizzaro","sequence":"additional","affiliation":[{"name":"Department of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90129 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Settimo, G., Manigrasso, M., and Avino, P. 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