{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T08:50:29Z","timestamp":1778662229573,"version":"3.51.4"},"reference-count":38,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Open Access Publishing Fund of Leipzig University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background: Current research is paying more attention to neurological outcomes and quality of life after life-threatening events. Children with heart disease are particularly vulnerable, especially after resuscitation events. While newer data show that adults with heart failure and a left-ventricular assist device suffer from a higher incidence of depression, mental health in pediatric heart disease patients is poorly understood. This is the first study in Germany to examine the quality of life and psychological burden in cardiac arrest survivors with congenital or acquired heart disease. Methods: This monocentric study retrospectively analyzed survival outcomes of pediatric heart disease patients who underwent in-hospital resuscitation between 2008 and 2022. The PedsQL and Strength and difficulties questionnaires were prospectively administered to survivors to assess quality of life and emotional\/behavioral problems, while academic achievements were additionally documented. Results: Of 127 patients experiencing cardiac arrest, 91 (71.7%) survived to discharge. Most had complex congenital heart diseases; mean cardiopulmonary resuscitation duration was 14 min. Five patients received extracorporeal cardiopulmonary resuscitation. Of the 22 patients who were receiving follow-up care at the pediatric cardiology outpatient clinic at the time of the study, 14 completed questionnaires were received. Overall quality of life was comparable to healthy controls, though those with prolonged or multiple resuscitations showed lower physical, emotional, social, and school functioning scores. The Strengths and Difficulties Questionnaire revealed no pathological scores but elevated average values for hyperactivity and emotional problems in parent reports, and emotional and peer difficulties in self-reports, indicating increased psychological burden. Conclusions: While survival rates are comparable to international data, gaps exist in structured follow-up and neuropsychological care, especially for high-risk subgroups like ECMO survivors. Routine neuropsychological screening and multidisciplinary outpatient programs are essential to improve long-term follow-up care.<\/jats:p>","DOI":"10.3390\/children12101397","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T12:17:02Z","timestamp":1760617022000},"page":"1397","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Quality of Life and Mental Health Problems in Pediatric Cardiac Arrest Survivors"],"prefix":"10.3390","volume":"12","author":[{"given":"Tina","family":"Schwartz","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University Leipzig, Augustusplatz 10, 04109 Leipzig, Germany"},{"name":"Heart Center Leipzig, University Hospital Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Weidenbach","sequence":"additional","affiliation":[{"name":"Heart Center Leipzig, University Hospital Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2773-689X","authenticated-orcid":false,"given":"Ingo","family":"D\u00e4hnert","sequence":"additional","affiliation":[{"name":"Heart Center Leipzig, University Hospital Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Paech","sequence":"additional","affiliation":[{"name":"Heart Center Leipzig, University Hospital Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franziska","family":"Markel","sequence":"additional","affiliation":[{"name":"Heart Center Leipzig, University Hospital Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"},{"name":"Department of Congenital Heart Disease\u2014Pediatric Cardiology, Deutsches Herzzentrum der Charit\u00e9, Augustenburger Platz1, 13353 Berlin, Germany"},{"name":"Deutsches Herzzentrum der Charit\u00e9, Department of Psychocardiology, Department of Developmental Pediatrics, Augustenburger Platz 1, 13353 Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Jung, P., Brenner, S., Bachmann, I., Both, C., Cardona, F., Dohna-Schwake, C., Eich, C., Eifinger, F., Huth, R., and Heimberg, E. 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