{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T23:17:06Z","timestamp":1790119026978,"version":"4.0.1"},"reference-count":23,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background\/Objectives: The optimal timing for inguinal hernia repair in premature infants remains controversial. Most premature patients in our institution undergo repair just before discharge. This study evaluates postoperative complications in premature patients and proposes the optimal timing for hernia repair. Methods: A retrospective single-center review was conducted between January 2020 and November 2023. All infants undergoing hernia repair as inpatients under 50 weeks postmenstrual age (PMA) were included. Data collected included demographic details, perioperative characteristics, and postoperative outcomes. Results: A total of 202 patients were analyzed. Forty-five patients underwent surgery before 38 weeks PMA (early group), and 157 after 38 weeks PMA (late group). The early group had significantly lower gestational age, lower body weight, and more comorbidities. Postoperative respiratory complications were more frequent in the early group. Conclusions: Repair after 38 weeks PMA is associated with fewer respiratory complications while earlier repair increases transient airway support requirements.<\/jats:p>","DOI":"10.3390\/children13010160","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T10:41:34Z","timestamp":1769164894000},"page":"160","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Optimal Timing of Inguinal Hernia Repair in Premature Infants: A Retrospective Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9551-6733","authenticated-orcid":false,"given":"Joshua Z. E.","family":"Yau","sequence":"first","affiliation":[{"name":"Division of Pediatric Surgery, MacKay Memorial Hospital, Taipei 104217, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3800-4301","authenticated-orcid":false,"given":"Paul C. Y.","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, MacKay Memorial Hospital, Taipei 104217, Taiwan"},{"name":"Department of Medicine, MacKay Medical University, New Taipei City 25245, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nien-Lu","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, MacKay Memorial Hospital, Taipei 104217, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Cherng","family":"Sheu","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, MacKay Memorial Hospital, Taipei 104217, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, MacKay Memorial Hospital, Taipei 104217, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ting","family":"Yeh","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, MacKay Memorial Hospital, Taipei 104217, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1651-2227.2004.tb00681.x","article-title":"Low prevalence of complications of delayed herniotomy in the extremely premature infant","volume":"93","year":"2004","journal-title":"Acta Paediatr."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e392","DOI":"10.1542\/neo.21-6-e392","article-title":"Inguinal hernia in premature infants","volume":"21","author":"Ramachandran","year":"2020","journal-title":"Neoreviews"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/S0022-3468(84)80379-6","article-title":"Inguinal hernia repair in the perinatal period and early infancy: Clinical considerations","volume":"19","author":"Rescorla","year":"1984","journal-title":"J. Pediatr. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Alqahtany, L.Y., Alsharif, A., Alsharif, A., Alanazi, O., Altaf, M., Kaleemullah, A., Alsaedi, L., Wasaya, H.I., Alharbi, A.H., and Bawazir, O. (2025). Impact of Surgical Timing on Outcomes in Neonatal Inguinal Hernia Repairs: A Systematic Review. Pediatr. Rep., 17.","DOI":"10.3390\/pediatric17010012"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s00383-010-2573-x","article-title":"Optimal timing for repair of an inguinal hernia in premature infants","volume":"26","author":"Vaos","year":"2010","journal-title":"Pediatr. Surg. Int."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1016\/j.jpedsurg.2018.02.056","article-title":"Inguinal hernia in preterms in neonatal intensive care units: Optimal timing of herniorrhaphy and necessity of contralateral exploration in unilateral presentation","volume":"53","author":"Youn","year":"2018","journal-title":"J. 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Surg."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/13\/1\/160\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T11:13:23Z","timestamp":1769166803000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/13\/1\/160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,22]]},"references-count":23,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1]]}},"alternative-id":["children13010160"],"URL":"https:\/\/doi.org\/10.3390\/children13010160","relation":{},"ISSN":["2227-9067"],"issn-type":[{"value":"2227-9067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,22]]}}}