{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:14:22Z","timestamp":1791598462211,"version":"4.3.4"},"reference-count":49,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background\/Objectives: This study aimed to compare clinical and psychosocial characteristics of substance-using adolescents in T\u00fcrkiye with and without a history of suicide attempts to identify distinguishing risk factors. Methods: A retrospective analysis was conducted using medical records from 140 adolescents (aged 13\u201318) treated at a specialized Child and Adolescent Substance Use Center in T\u00fcrkiye between March 2023 and February 2025. Sociodemographic, clinical, and substance use data were collected. Group comparisons were performed using chi-square and t-tests. Logistic regression was used to identify predictors of suicide attempt history. Results: Among the sample, 52 adolescents (37.1%) had a history of suicide attempts. Compared to their counterparts, the substance-using adolescents were more likely to be female (73.1%) and have histories of psychiatric hospitalization, institutional care, criminal behavior, and polysubstance use (p &lt; 0.05). High-frequency use (\u22653 days\/week) of methamphetamine, stimulants, cannabinoids, and alcohol was significantly more common in this group (all p &lt; 0.01). The Addiction Profile Index\u2013Adolescent form (API-A) scores indicated more severe addiction profiles. Using cross-validated LASSO and confirmatory logistic regression, female gender emerged as the only robust independent predictor of suicide attempt history (OR = 6.84). Conclusions: Adolescents with a history of suicide attempts exhibit more severe substance use, particularly involving cannabinoids, and greater psychosocial adversity. This distinct risk profile underscores the need for early, gender-sensitive, and multidimensional interventions.<\/jats:p>","DOI":"10.3390\/children13020186","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T09:12:01Z","timestamp":1769677921000},"page":"186","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Substance Use and Suicide Attempts in Adolescents: A Comparative Analysis of Clinical and Psychosocial Risk Factors"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8418-4745","authenticated-orcid":false,"given":"Mustafa Tolga","family":"Tunagur","sequence":"first","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Faculty of Medicine, Sakarya University, Serdivan 54290, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elif Merve","family":"Kurt Tunagur","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Faculty of Medicine, \u00c7anakkale Onsekiz Mart University, \u00c7anakkale 17020, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Yu, C., and Chen, J. 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