{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T14:06:56Z","timestamp":1784729216298,"version":"3.55.0"},"reference-count":18,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Neonatal renal tumors are uncommon and generally associated with an excellent prognosis. We report the youngest patient to date with unilateral non-syndromic Wilms tumor successfully treated with nephron-sparing surgery rather than radical nephrectomy, which is the current standard of care. The patient subsequently received risk-adapted chemotherapy. At 18 months of follow-up, he remains asymptomatic and with symmetric differential renal volumes, consistent with preserved bilateral renal function. This case suggests that nephron-sparing surgery, when technically feasible, may represent a safe and effective treatment option for carefully selected neonatal renal tumors, offering a functional advantage over radical nephrectomy without compromising oncologic safety.<\/jats:p>","DOI":"10.3390\/children13070966","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T13:25:46Z","timestamp":1784726746000},"page":"966","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nephron-Sparing Surgery for Unilateral Non-Syndromic Wilms Tumor in a 9-Day-Old Neonate"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1649-1038","authenticated-orcid":false,"given":"Silvia","family":"Ceccanti","sequence":"first","affiliation":[{"name":"Pediatric Surgery Unit, Department Maternal Infantile and Urological Sciences, AOU Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5887-813X","authenticated-orcid":false,"given":"Francesco","family":"Morini","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit, Department Maternal Infantile and Urological Sciences, AOU Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1950-4754","authenticated-orcid":false,"given":"Loredana","family":"Amoroso","sequence":"additional","affiliation":[{"name":"Pediatric Oncology Unit, Department Maternal Infantile and Urological Sciences, AOU Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Marco","family":"Andreoli","sequence":"additional","affiliation":[{"name":"Pediatric Radiology Unit, Department of Radiological, Oncological, Pathological Anatomy Sciences, AOU Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Masselli","sequence":"additional","affiliation":[{"name":"Emergency Radiology Unit, Department of Radiological, Oncological, Pathological Anatomy Sciences, AOU Policlinico Umberto I, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7290-3837","authenticated-orcid":false,"given":"Denis A.","family":"Cozzi","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Unit, Department Maternal Infantile and Urological Sciences, AOU Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/j.jpedsurg.2008.03.052","article-title":"Fetal and neonatal renal tumors","volume":"43","author":"Isaacs","year":"2008","journal-title":"J. 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