{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T10:20:57Z","timestamp":1787566857204,"version":"build-2736575974"},"reference-count":34,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T00:00:00Z","timestamp":1787443200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"LILT"},{"id":[{"id":"https:\/\/ror.org\/02r2t8x54","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background\/Objectives: Exercise medicine is gaining significant importance in adult oncology to improve physical activity and quality of life (QoL). However, few studies have investigated the effects of adapted physical activities in the pediatric population. The aim of this secondary analysis is to compare the movement quality of a hematological\/oncological pediatric population before and after an individualized exercise program (IEP). Methods: Participants who met the inclusion criteria (aged 5\u201318 years, oncological\/hematological diagnosis, consent) underwent an IEP delivered both in the hospital and via telemedicine at home. The subject\u2019s movement quality was assessed before and after six months of the IEP using instrumented functional tests (i.e., 6 min walking test, Timed Up and Go, T25-FW, and turning test). To reduce the number of variables obtained, principal component analysis (PCA) was performed, and the resulting scores were then compared. Results: A total of 18 subjects (median age 12 years; eight females) were included in the analysis. Through the PCA, four dimensions were identified: Gait Efficiency, Gait Quality, Dynamic Balance, and Functional Abilities. The pre\u2013post comparison showed significant improvements (p = 0.002) in Dynamic Balance and a trend (p = 0.05) in Gait Efficiency. Conclusions: The presented results indicate the crucial Principal Components (PCs) of movement in children treated for cancer. Moreover, in our setting, under the IEP we observed a significant improvement in Dynamic Balance. The results are consistent with those observed in previous studies. However, the limited number of subjects and the study design preclude definitive conclusions.<\/jats:p>","DOI":"10.3390\/children13091127","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T08:03:41Z","timestamp":1787558621000},"page":"1127","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gait and Functional Movement Quality Improvements Following an Individualized Exercise Program in Pediatric Hemato-Oncological Patients"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9914-4882","authenticated-orcid":false,"given":"Linda","family":"Peli","sequence":"first","affiliation":[{"name":"Lega Italiana Lotta Tumori (LILT), 25128 Brescia, Italy"},{"name":"Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1568-9069","authenticated-orcid":false,"given":"Joel","family":"Pollet","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy"},{"name":"IRCCS Fondazione Don Carlo Gnocchi, 20162 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Finazzi","sequence":"additional","affiliation":[{"name":"Lega Italiana Lotta Tumori (LILT), 25128 Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Inselvini","sequence":"additional","affiliation":[{"name":"Lega Italiana Lotta Tumori (LILT), 25128 Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3614-8691","authenticated-orcid":false,"given":"Vincenzo","family":"Pintabona","sequence":"additional","affiliation":[{"name":"Pediatric Oncohematology and Bone Marrow Transplant Unit, Ospedale Dei Bambini, ASST Spedali Civili of Brescia, 25123 Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Sedaboni","sequence":"additional","affiliation":[{"name":"Pediatric Oncohematology and Bone Marrow Transplant Unit, Ospedale Dei Bambini, ASST Spedali Civili of Brescia, 25123 Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Gorio","sequence":"additional","affiliation":[{"name":"Pediatric Oncohematology and Bone Marrow Transplant Unit, Ospedale Dei Bambini, ASST Spedali Civili of Brescia, 25123 Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1346-9580","authenticated-orcid":false,"given":"Richard Fabian","family":"Schumacher","sequence":"additional","affiliation":[{"name":"Pediatric Oncohematology and Bone Marrow Transplant Unit, Ospedale Dei Bambini, ASST Spedali Civili of Brescia, 25123 Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulvio","family":"Porta","sequence":"additional","affiliation":[{"name":"Pediatric Oncohematology and Bone Marrow Transplant Unit, Ospedale Dei Bambini, ASST Spedali Civili of Brescia, 25123 Brescia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1383-6213","authenticated-orcid":false,"given":"Massimiliano","family":"Gobbo","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy"},{"name":"IRCCS Fondazione Don Carlo Gnocchi, 20162 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S2352-4642(18)30095-6","article-title":"Causes of death among children aged 5\u201314 years in the WHO European Region: A systematic analysis for the Global Burden of Disease Study 2016","volume":"2","author":"Kyu","year":"2018","journal-title":"Lancet Child Adolesc. 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