{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:00:17Z","timestamp":1789988417099,"version":"4.0.1"},"reference-count":39,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background\/Objectives: The transition from paediatric to adult care in inflammatory bowel disease (IBD) is a period of genuine clinical vulnerability. Despite international guidelines, real-world implementation of transition programmes remains inconsistent and the field lacks consensus on clinically meaningful outcome measures. We introduce the concept of \u201ctransition failure\u201d as a provisional composite outcome framework to reorient research toward patient-centred endpoints. Methods: A narrative search of PubMed, MEDLINE, and Embase was conducted using terms including \u201cinflammatory bowel disease\u201d, \u201ctransition\u201d, \u201ctransfer to adult care\u201d, and \u201cadherence\u201d; no formal quality appraisal was applied. The search covered the databases from inception to 30 June 2026. Results: We synthesise current evidence on transition readiness and its limitations, delineate patient- and system-level barriers\u2014including the underappreciated role of parental involvement\u2014and characterise high-risk subgroups. Five evidence-informed, provisional domains of transition failure are proposed. Where published data permit, illustrative quantitative benchmarks are described; however, these are not assumed to be universally applicable across therapies or disease phenotypes. A composite of \u22652 domains within 24 months is proposed as a candidate research classification rule pending prospective validation, rather than as a clinical diagnostic threshold. Conclusions: The transition failure framework provides a hypothesis-generating construct for evaluating transition quality. Prospective multicentre validation, standardised and therapy-specific outcome definitions, adjustment for baseline disease severity, and risk-stratified multidisciplinary programmes are identified as research priorities.<\/jats:p>","DOI":"10.3390\/children13091270","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T09:01:38Z","timestamp":1789981298000},"page":"1270","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transition Failure in Pediatric Inflammatory Bowel Disease: An Underrecognized Determinant of Long-Term Outcomes"],"prefix":"10.3390","volume":"13","author":[{"given":"Frank Risto","family":"Rommel","sequence":"first","affiliation":[{"name":"Department of General Pediatrics, University Children\u2019s Hospital Marburg, University of Marburg, 35408 Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Schumann","sequence":"additional","affiliation":[{"name":"Department of General Pediatrics and Neonatology, University of Giessen, 35392 Giessen, Germany"},{"name":"DRK-Kinderklinik Siegen, 57072 Siegen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9498-2337","authenticated-orcid":false,"given":"Stefanie","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of General Pediatrics, University Children\u2019s Hospital Marburg, University of Marburg, 35408 Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4008-7185","authenticated-orcid":false,"given":"Andreas","family":"Jenke","sequence":"additional","affiliation":[{"name":"Department of Neonatology and Pediatric Gastroenterology, Children\u2019s Hospital Kassel, Klinikum Kassel, 34125 Kassel, Germany"},{"name":"Department of Medicine, Faculty of Health, University of Witten\/Herdecke, 58455 Witten, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1053\/j.gastro.2021.12.282","article-title":"Twenty-first Century Trends in the Global Epidemiology of Pediatric-Onset Inflammatory Bowel Disease: Systematic Review","volume":"162","author":"Kuenzig","year":"2022","journal-title":"Gastroenterology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1093\/ecco-jcc\/jjaa161","article-title":"The Medical Management of Paediatric Crohn\u2019s Disease: An ECCO-ESPGHAN Guideline Update","volume":"15","author":"Aloi","year":"2021","journal-title":"J. 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