{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:09:57Z","timestamp":1785802197759,"version":"3.56.0"},"reference-count":10,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2017,9,29]],"date-time":"2017-09-29T00:00:00Z","timestamp":1506643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>The treatment of epilepsy with vagus nerve stimulation can inadvertently cause obstructive and central sleep apnea (CSA). The mechanism for CSA seen in patients with a vagus nerve stimulator (VNS) is not fully known. We describe the case of a 13-year-old girl in whom VNS activation induced tachypnea and post-hyperventilation central apnea. Following adjustment of VNS settings, the post-hyperventilation CSA resolved. Polysomnography may assist with management when patients with epilepsy develop sleep disruption after VNS placement.<\/jats:p>","DOI":"10.3390\/children4100086","type":"journal-article","created":{"date-parts":[[2017,9,29]],"date-time":"2017-09-29T12:24:04Z","timestamp":1506687844000},"page":"86","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["A Potential Novel Mechanism for Vagus Nerve Stimulator-Related Central Sleep Apnea"],"prefix":"10.3390","volume":"4","author":[{"given":"Inga","family":"Forde","sequence":"first","affiliation":[{"name":"Center for Sleep Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghna","family":"Mansukhani","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhanu","family":"Kolla","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine and Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Kotagal","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine and Division of Pediatric Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2017,9,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1528-1157.1989.tb05331.x","article-title":"Identification of a median thalamic system regulating seizures and arousal","volume":"30","author":"Miller","year":"1989","journal-title":"Epilepsia"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"401","DOI":"10.5664\/JCSM.1204","article-title":"Obstructive sleep apnea and respiratory complications associated with vagus nerve stimulators","volume":"7","author":"Parhizgar","year":"2011","journal-title":"J. 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