{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T14:00:22Z","timestamp":1793196022249,"version":"4.5.0"},"reference-count":60,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T00:00:00Z","timestamp":1584662400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Global Affairs Canada through Savanna Signatures, Tamale, Ghana","award":["n\/a"],"award-info":[{"award-number":["n\/a"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Optimum care of sick neonates often involves transporting them across different levels of care. Since their condition may deteriorate over time, attention needs to be paid to travel distances and how they are transferred. We examined the mode of transport, distances travelled, condition on arrival and outcome of outborn neonates admitted to a district and a regional hospital in Ghana using a cross-sectional study involving caregivers of neonates admitted to these hospitals. Information on referral characteristics and outcome were obtained from questionnaires and the child\u2019s case notes. Overall, 153 caregivers and babies were studied. Twelve deaths, 7.8%, occurred. Neonates who died spent a median duration of 120 min at the first health facility they visited compared with 30 min spent by survivors; they travelled mostly by public buses, (41.7%), compared with 36.0% of survivors who used taxis. Majority of survivors, 70.2%, had normal heart rates on arrival compared with only 41.7% of neonates who died; hypothermia was present in 66.7% compared with 47.6% of survivors. These findings indicate that the logistics for neonatal transport were inadequate to keep the neonates stable during the transfer process, thus many of them were compromised especially those who died. Further studies are warranted.<\/jats:p>","DOI":"10.3390\/children7030022","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T07:29:07Z","timestamp":1584689347000},"page":"22","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The Transport and Outcome of Sick Outborn Neonates Admitted to a Regional and District Hospital in the Upper West Region of Ghana: A Cross-Sectional Study"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8219-6980","authenticated-orcid":false,"given":"Edem M. A.","family":"Tette","sequence":"first","affiliation":[{"name":"Department of Community Health, University of Ghana Medical School, P.O. Box 4236, Accra, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4946-508X","authenticated-orcid":false,"given":"Benjamin D.","family":"Nuertey","sequence":"additional","affiliation":[{"name":"Department of Community Health, University of Ghana Medical School, P.O. Box 4236, Accra, Ghana"},{"name":"Public Health Department, Tamale Teaching Hospital, P.O. Box TL 16, Tamale, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic","family":"Akaateba","sequence":"additional","affiliation":[{"name":"Upper West Regional Hospital, P.O. Box 6, Wa, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naa Barnabas","family":"Gandau","sequence":"additional","affiliation":[{"name":"Upper West Regional Hospital, P.O. Box 6, Wa, Ghana"},{"name":"School of Medical Science, University for Development Studies, P.O. Box TL 1350, Tamale, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,3,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S0140-6736(05)71048-5","article-title":"4 million neonatal deaths: When? Where? Why?","volume":"365","author":"Lawn","year":"2005","journal-title":"Lancet"},{"key":"ref_2","unstructured":"(2015). UNICEF, WHO, World Bank, UN-DESA Population Levels and Trends in Child Mortality: Report 2015: the UN Inter-Agency Group for Child Mortality Estimation, United Nations Children\u2019s Fund."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0140-6736(14)60792-3","article-title":"Can available interventions end preventable deaths in mothers, newborn babies, and stillbirths, and at what cost?","volume":"384","author":"Bhutta","year":"2014","journal-title":"Lancet"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e002326","DOI":"10.1136\/bmjopen-2012-002326","article-title":"Quality of newborn care: a health facility assessment in rural Ghana using survey, vignette and surveillance data","volume":"3","author":"Vesel","year":"2013","journal-title":"BMJ Open"},{"key":"ref_5","unstructured":"World Health Organization (2016). Standards for Improving Quality of Maternal and Newborn Care in Health Facilities, WHO."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"M\u00e5lqvist, M., Sohel, N., Do, T.T., Eriksson, L., and Persson, L.-\u00c5. (2010). Distance decay in delivery care utilisation associated with neonatal mortality. A case referent study in northern Vietnam. BMC Public Health, 10.","DOI":"10.1186\/1471-2458-10-762"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1365-3156.2007.01981.x","article-title":"Beyond symptom recognition: care-seeking for ill newborns in rural Ghana","volume":"13","author":"Bazzano","year":"2008","journal-title":"Trop. Med. Int. Health"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1136\/bmj.3.5718.328","article-title":"Transport of sick newborn babies","volume":"3","author":"Storrs","year":"1970","journal-title":"Br. Med. J."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Nlend, A.E.N., Zeudja, C., and Nsoa, L. (2016). Transfert et transport des nouveau-n\u00e9s en situation de d\u00e9tresse vitale \u00e0 Yaound\u00e9, Cameroun: analyse situationnelle dans un h\u00f4pital de r\u00e9f\u00e9rence. Pan. Afr. Med. J., 25.","DOI":"10.11604\/pamj.2016.25.214.9642"},{"key":"ref_10","unstructured":"Niermeyer, S., and Domek, G. (2020, February 24). Neonatal transport in developing country settings: A systematic review. Pan American Health Organisation, Montevido. Available online: http:\/\/iris.paho.org\/xmlui\/handle\/123456789\/31317."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e001196","DOI":"10.1136\/bmjopen-2012-001196","article-title":"Proximity to health services and child survival in low-and middle-income countries: a systematic review and meta-analysis","volume":"2","author":"Okwaraji","year":"2012","journal-title":"BMJ Open"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/aje\/kwq386","article-title":"The effect of distance to health-care facilities on childhood mortality in rural Burkina Faso","volume":"173","author":"Schoeps","year":"2011","journal-title":"Am. J. Epidemiol."},{"key":"ref_13","first-page":"817","article-title":"Facility distance and child mortality: A multi-country study of health facility access, service utilization, and child health outcomes","volume":"46","author":"Karra","year":"2017","journal-title":"Int. J. Epidemiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1093\/oxfordjournals.pan.a004868","article-title":"Logistic regression in rare events data. Political Analysis","volume":"9","author":"King","year":"2001","journal-title":"Polit Anal."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"F212","DOI":"10.1136\/adc.2003.046201","article-title":"Contemporary neonatal transport: problems and solutions","volume":"89","author":"Cornette","year":"2004","journal-title":"Arch. Dis. Childhood Fetal Neonatal Ed."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"481","DOI":"10.3345\/kjp.2011.54.12.481","article-title":"Regionalization of neonatal intensive care in Korea","volume":"54","author":"Chang","year":"2011","journal-title":"Korean J. Pediatr."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1177\/0049475514564270","article-title":"Transport of sick neonates to a tertiary care hospital, south India: condition at arrival and outcome","volume":"45","author":"Rathod","year":"2015","journal-title":"Trop Doct."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Nalwadda, C.K., Waiswa, P., Kiguli, J., Namazzi, G., Namutamba, S., Tomson, G., and Guwatudde, D. (2013). High Compliance with Newborn Community-to-Facility Referral in Eastern Uganda: An Opportunity to Improve Newborn Survival. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0081610"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Kozuki, N., Guenther, T., Vaz, L., Moran, A., Soofi, S.B., Kayemba, C.N., and Doherty, T. (2015). A systematic review of community-to-facility neonatal referral completion rates in Africa and Asia. BMC Public Health, 15.","DOI":"10.1186\/s12889-015-2330-0"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"566","DOI":"10.4103\/0975-2870.192156","article-title":"Neonatal transport in India: From public health perspective","volume":"9","author":"Roy","year":"2016","journal-title":"Med J. Dr DY Patil Univ."},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Hedstrom, A., Ryman, T., Otai, C., Nyonyintono, J., McAdams, R.M., Lester, D., and Batra, M. (2014). Demographics, clinical characteristics and neonatal outcomes in a rural Ugandan NICU. BMC Pregnancy Childbirth, 14.","DOI":"10.1186\/1471-2393-14-327"},{"key":"ref_22","first-page":"209","article-title":"Mortality Among Outborn Versus Inborn Neonates: A Retrospective Comparative Study","volume":"77","author":"Elwan","year":"2009","journal-title":"Med. J. Cairo Univ."},{"key":"ref_23","unstructured":"Ghana Statistical Service (2013). 2010 Population & Housing Census: National Analytical Report, Ghana Statistical Service."},{"key":"ref_24","unstructured":"Ghana Health Service (2019, February 16). Upper West Region\u2014Upper West Regional Directorate. Upper West Region. Available online: http:\/\/www.ghanahealthservice.org\/rhdcategory.php?ghsrid=3&cid=39."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/S0140-6736(10)62226-X","article-title":"Normal ranges of heart rate and respiratory rate in children from birth to 18 years of age: a systematic review of observational studies","volume":"377","author":"Fleming","year":"2011","journal-title":"Lancet"},{"key":"ref_26","unstructured":"World Health Organization (1993). Thermal Control of the Newborn: A Practical Guide, World Health Organization."},{"key":"ref_27","first-page":"34","article-title":"Neonatal pre-transport stabilisation\u2013caring for infants the STABLE way","volume":"1","author":"Mears","year":"2005","journal-title":"Infant"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"233","DOI":"10.21037\/tp.2019.07.04","article-title":"Neonatal transport metrics and quality improvement in a regional transport service","volume":"8","author":"Lee","year":"2019","journal-title":"Transl. Pediatr."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"435","DOI":"10.4103\/2249-4863.161348","article-title":"Mortality in newborns referred to tertiary hospital: An introspection","volume":"4","author":"Aggarwal","year":"2015","journal-title":"J. Family Med. Prim. Care"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Abdulraheem, M.A., Tongo, O.O., Orimadegun, A.E., and Akinbami, O.F. (2016). Neonatal transport practices in Ibadan, Nigeria. Pan Afr. Med J., 24.","DOI":"10.11604\/pamj.2016.24.216.8651"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3329\/bjch.v41i3.36951","article-title":"Transport Factors Affecting the Outcome of Referred Neonates Admitted in A Tertiary Care Hospital","volume":"41","author":"Baidya","year":"2017","journal-title":"Bangladesh J. Child Health"},{"key":"ref_32","first-page":"169","article-title":"Neonatal Transport\u2014Experience of a Tertiary Care Hospital of Bangladesh","volume":"26","author":"Dey","year":"2017","journal-title":"Mymensingh Med. J."},{"key":"ref_33","first-page":"265","article-title":"The interfacility transport of critically ill newborns","volume":"20","author":"Whyte","year":"2015","journal-title":"None"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Nimbalkar, S., Patel, H., Dongara, A., Patel, D.V., and Bansal, S. (2014). Usage of EMBRACETM in Gujarat, India: Survey of Paediatricians. Adv. Prev. Med.","DOI":"10.1155\/2014\/415301"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1152\/japplphysiol.00799.2009","article-title":"Why wrapping premature neonates to prevent hypothermia can predispose to overheating","volume":"108","author":"Agourram","year":"2010","journal-title":"J. Appl. Physiol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/j.1440-1754.1997.tb01628.x","article-title":"Control of temperature during newborn transport: an old problem with new difficulties","volume":"33","author":"Bowman","year":"1997","journal-title":"J. Paediatr. Child Health"},{"key":"ref_37","unstructured":"Advanced Life Support Group (ALSG) (2011). Advanced Paediatric Life Support: The Practical Approach, BMJ Books. [5th ed.]."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"F177","DOI":"10.1136\/adc.2009.169102","article-title":"Changes in heart rate in the first minutes after birth","volume":"95","author":"Dawson","year":"2010","journal-title":"Arch. Dis. Childhood Fetal Neonatal Ed."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Chong, S.L., Ong, G.Y.K., Chin, W.Y.W., Chua, J.M., Nair, P., Ong, A.S.Z., and Maconochie, I. (2018). A retrospective review of vital signs and clinical outcomes of febrile infants younger than 3 months old presenting to the emergency department. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0190649"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1203\/01.pdr.0000252438.65759.af","article-title":"Heart rate characteristics and clinical signs in neonatal sepsis","volume":"61","author":"Griffin","year":"2007","journal-title":"Pediatric Res."},{"key":"ref_41","first-page":"307","article-title":"Challenges in neonatal transport in Jamaica: A resource-limited setting","volume":"63","author":"Henry","year":"2017","journal-title":"J. Trop. Pediatrics"},{"key":"ref_42","first-page":"S18","article-title":"Turkish Neonatal Society guideline on the safe transport of newborn","volume":"25","author":"Narli","year":"2018","journal-title":"Turk Pediatri Ars."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"244","DOI":"10.4103\/ijcm.IJCM_154_16","article-title":"Neonatal transport: The long drive has not even begun","volume":"42","author":"Jajoo","year":"2017","journal-title":"Indian J. Community Med."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"514","DOI":"10.7196\/SAMJ.2016.v106i5.8554","article-title":"An analysis of inter-healthcare facility transfer of neonates within the eThekwini Health District of KwaZulu-Natal, South Africa","volume":"106","author":"Ashokcoomar","year":"2016","journal-title":"South Afr. Med J."},{"key":"ref_45","first-page":"55","article-title":"A Study on The Current Status of Neonatal Transport to A Special Newborn Care Unit","volume":"3","author":"Punitha","year":"2016","journal-title":"Stanley Med J."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"e021223","DOI":"10.1136\/bmjopen-2017-021223","article-title":"Perceived barriers to maternal and newborn health services delivery: a qualitative study of health workers and community members in low and middle-income settings","volume":"8","author":"Sumankuuro","year":"2018","journal-title":"BMJ Open"},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Tette, E., Nuertey, B.D., Azusong, E.A., and Gandau, N.B. (2020). The Profile, Health Seeking Behavior, Referral Patterns, and Outcome of Outborn Neonates Admitted to a District and Regional Hospital in the Upper West Region of Ghana: A Cross-Sectional Study. Children, 7.","DOI":"10.3390\/children7020015"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"100","DOI":"10.4103\/0019-557X.115003","article-title":"Predictors of mortality among the neonates transported to referral centre in Delhi, India","volume":"57","author":"Narang","year":"2013","journal-title":"Indian J. Public Health"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1136\/adc.79.1.65","article-title":"Where should paediatric surgery be performed?","volume":"79","author":"Arul","year":"1998","journal-title":"Archives Dis. Child."},{"key":"ref_50","first-page":"123","article-title":"Newborn haemorrhagic disorders: About 30 cases","volume":"28","author":"Karboubi","year":"2017","journal-title":"Pan Afr. Med. J."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s12098-009-0336-2","article-title":"Prolonged neonatal interhospital transport on road: relevance for developing countries","volume":"77","author":"Kumar","year":"2010","journal-title":"Indian J. Pediatrics"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1136\/bmj.311.7009.836","article-title":"Morbidity and severity of illness during interhospital transfer: impact of a specialised paediatric retrieval team","volume":"311","author":"Britto","year":"1995","journal-title":"BMJ"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s13054-015-0749-4","article-title":"Transferring the critically ill patient: are we there yet?","volume":"19","author":"Droogh","year":"2015","journal-title":"Critical Care"},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Accorsi, S., Somigliana, E., Solomon, H., Ademe, T., Woldegebriel, J., Almaz, B., and Seifu, A. (2017). Cost-effectiveness of an ambulance-based referral system for emergency obstetrical and neonatal care in rural Ethiopia. BMC Pregnancy Childbirth, 17.","DOI":"10.1186\/s12884-017-1403-8"},{"key":"ref_55","unstructured":"Ghana Health Service (2019). Ghana National Newborn Health Strategy and Action Plan 2019-2023."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1542\/peds.2013-0529","article-title":"Pediatric and neonatal interfacility transport: results from a national consensus conference","volume":"132","author":"Stroud","year":"2013","journal-title":"Pediatrics"},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Tette, E.M., Neizer, M., Nyarko, M.Y., Sifah, E.K., Nartey, E.T., and Donkor, E.S. (2016). Changing patterns of disease and mortality at the Children\u2019s Hospital, Accra: are infections rising?. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0150387"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1080\/17441692.2015.1027247","article-title":"Conducting an audit to improve the facilitation of emergency maternal and newborn referral in northern Ghana","volume":"10","author":"Bailey","year":"2015","journal-title":"Global Public Health"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0140-6736(02)07373-7","article-title":"Descriptive studies: what they can and cannot do","volume":"359","author":"Grimes","year":"2002","journal-title":"Lancet"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"34","DOI":"10.4103\/picr.PICR_154_18","article-title":"Study designs: Part 2\u2014Descriptive studies","volume":"10","author":"Aggarwal","year":"2019","journal-title":"Perspect. Clin. Res."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/7\/3\/22\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T09:10:02Z","timestamp":1760173802000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/7\/3\/22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,20]]},"references-count":60,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,3]]}},"alternative-id":["children7030022"],"URL":"https:\/\/doi.org\/10.3390\/children7030022","relation":{},"ISSN":["2227-9067"],"issn-type":[{"value":"2227-9067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,20]]}}}