{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:05:41Z","timestamp":1760238341221,"version":"build-2065373602"},"reference-count":11,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T00:00:00Z","timestamp":1596412800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Splenic abscess occurs very rarely in healthy children. Although typhoid fever was the leading cause of splenic abscess in the pre-antibiotic era, Salmonella spp. remain to be the major pathogens causing splenic abscess, with an increasing worldwide frequency of splenic abscess due to non-typhoidal Salmonella infection. Here, we report the case of a 12-year-old boy, who was presumably diagnosed with acute gastroenteritis on admission and eventually diagnosed with a large splenic abscess (maximum diameter, 14.5 cm) caused by non-typhoidal Salmonella. Although splenectomy has been considered in cases of large splenic abscesses, the patient was treated with antibiotics and ultrasonography-guided percutaneous drainage. A detailed physical examination and appropriate imaging studies are necessary for the early diagnosis of extra-intestinal complications of non-typhoidal Salmonella enteritis. For treatment, percutaneous drainage, rather than splenectomy, can be used in large splenic abscesses.<\/jats:p>","DOI":"10.3390\/children7080088","type":"journal-article","created":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T06:16:47Z","timestamp":1596435407000},"page":"88","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Large Splenic Abscess Caused by Non-Typhoidal Salmonella in a Healthy Child Treated with Percutaneous Drainage"],"prefix":"10.3390","volume":"7","author":[{"given":"Hyun Woo","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1299-2137","authenticated-orcid":false,"given":"Seung Beom","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,8,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/0002-9343(76)90331-4","article-title":"Splenic abscess: Report of 10 cases and review of the literature","volume":"61","author":"Chulay","year":"1976","journal-title":"Am. J. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1007\/s00383-013-3336-2","article-title":"Isolated splenic abscess in children, role of splenic preservation","volume":"29","author":"Faruque","year":"2013","journal-title":"Pediatr. Surg. Int."},{"key":"ref_3","unstructured":"Bennett, J., Dolin, R., and Blaser, M.J. (2018). Splenic abscess. Mandell, Douglas, and Bennett\u2019s Principles and Practice of Infectious Diseases, Elsevier. [9th ed.]."},{"key":"ref_4","unstructured":"Cherry, J.D., Harison, G.J., Kaplan, S.L., Steinbach, W.J., and Hotez, P.J. (2019). Salmonella. Feigin\u2019s Textbook of Pediatric Infectious Diseases, Saunders. [8th ed.]."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"941","DOI":"10.3201\/eid2106.140999","article-title":"Global burden of invasive nontyphoidal Salmonella disease, 2010","volume":"21","author":"Ao","year":"2015","journal-title":"Emerg. Infect. Dis."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/s100960000341","article-title":"Enteric fever and other extraintestinal salmonellosis in University Hospital, Nottingham, UK, between 1980 and 1997","volume":"19","author":"Ispahani","year":"2000","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1159\/000107718","article-title":"Splenic abscesses caused by a reptile-associated salmonella infection","volume":"24","author":"Berendes","year":"2007","journal-title":"Dig. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jpedsurg.2008.01.066","article-title":"Partial laparoscopic splenectomy for splenic abscess because of Salmonella infection: A case report","volume":"43","author":"Hoffman","year":"2008","journal-title":"J. Pediatr. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"7341","DOI":"10.3748\/wjg.v12.i45.7341","article-title":"Ultrasound guided percutaneous treatment for splenic abscesses: The significance in treatment of critically ill patients","volume":"12","author":"Zerem","year":"2006","journal-title":"World J. Gastroenterol."},{"key":"ref_10","first-page":"740","article-title":"Splenic abscess: Outcome and prognostic factors","volume":"18","author":"Alvi","year":"2008","journal-title":"J. Coll. Physicians Surg. Pak."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1055\/s-0032-1330064","article-title":"Image-guided percutaneous splenic biopsy and drainage","volume":"29","author":"Sammon","year":"2012","journal-title":"Semin. Intervent. Radiol."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/7\/8\/88\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T09:53:52Z","timestamp":1760176432000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/7\/8\/88"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,3]]},"references-count":11,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020,8]]}},"alternative-id":["children7080088"],"URL":"https:\/\/doi.org\/10.3390\/children7080088","relation":{},"ISSN":["2227-9067"],"issn-type":[{"type":"electronic","value":"2227-9067"}],"subject":[],"published":{"date-parts":[[2020,8,3]]}}}