{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T08:33:43Z","timestamp":1783154023696,"version":"3.54.6"},"reference-count":13,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:00:00Z","timestamp":1598572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>The incidence of congenital lobar overinflation (CLO) is reported at 1 in 20,000\u201330,000 live births and represents 10% of all congenital lung malformations. The occurrence of concomitant congenital heart disease (CHD) and CLO ranges from 12% to 20%. There are diverging views in the management as to whether early lobectomy or repair of the cardiac defect, with the assumption that respiratory symptomatology would gradually resolve, or a combined lung and cardiac repair would be the ideal first step in the management. In concomitant CLO and CHD, the surgical decision has to be individualized. Prior to surgical intervention a thorough evaluation may be needed with contrast computed tomography (CT) or magnetic resonance imaging (MRI), bronchoscopy, and if needed cardiac catheterization. CLO improves with management of many left to right shunts and in those with anomalous vessels, but early lobectomy or combined approach may be considered in those symptomatic patients with more complex CHD.<\/jats:p>","DOI":"10.3390\/children7090113","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T09:17:08Z","timestamp":1598606228000},"page":"113","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Managing Congenital Lobar Overinflation Associated with Congenital Heart Disease"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9666-6883","authenticated-orcid":false,"given":"Ranjit I.","family":"Kylat","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Arizona, 1501 N Campbell Ave, Tucson, AZ 85724, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,8,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.jpedsurg.2019.02.043","article-title":"Current operative management of congenital lobar emphysema in children: A report from the Midwest Pediatric Surgery Consortium","volume":"54","author":"Kunisaki","year":"2019","journal-title":"J. Pediatr. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"150821","DOI":"10.1053\/j.sempedsurg.2019.07.004","article-title":"Congenital lung lesions","volume":"28","author":"Zobel","year":"2019","journal-title":"Semin. Pediatr. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/j.jpedsurg.2006.02.011","article-title":"Is congenital lobar emphysema a surgical disease?","volume":"41","author":"Konen","year":"2006","journal-title":"J. Pediatr. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"E644","DOI":"10.1532\/HSF98.20041041","article-title":"Surgical management of infants with congenital lobar emphysema and concomitant congenital heart disease","volume":"7","author":"Dogan","year":"2004","journal-title":"Heart Surg. Forum"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1007\/s00431-013-2249-3","article-title":"Congenital lobar emphysema causing discrepancy between size and symptoms of ventricular septal defect","volume":"173","author":"Noten","year":"2014","journal-title":"Eur. J. Pediatr."},{"key":"ref_6","first-page":"269","article-title":"Spontaneous regression of left upper lobe emphysema after division of large ductus arteriosus in an infant","volume":"48","author":"Duman","year":"2006","journal-title":"Turk. J. Pediatr."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1016\/S0003-4975(02)04623-4","article-title":"Lobar emphysema due to ductus arteriosus compressing right upper bronchus in an infant with congenital heart disease","volume":"75","author":"Hishitani","year":"2003","journal-title":"Ann. Thorac. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1007\/s00247-009-1530-0","article-title":"Rudhe syndrome: Reversible right middle lobe emphysema in infants with left-to-right shunts\u2014An historical review","volume":"40","author":"Collins","year":"2010","journal-title":"Pediatr. Radiol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"901","DOI":"10.5761\/atcs.cr.13-00186","article-title":"Ventricular septal defect complicated by infantile lobar emphysema","volume":"20","author":"Nakata","year":"2014","journal-title":"Ann. Thorac. Cardiovasc. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1017\/S1047951100005035","article-title":"Lobar emphysema due to anomalous aortic origin of the left pulmonary artery","volume":"9","author":"Absher","year":"1999","journal-title":"Cardiol. Young"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1053\/jpsu.2001.27067","article-title":"Infantile lobar emphysema and tracheal bronchus in a patient with congenital heart disease","volume":"36","author":"Elmaci","year":"2001","journal-title":"J. Pediatr. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.hlc.2011.04.038","article-title":"Pulmonary emphysematous changes in patients with congenital heart disease associated with increased pulmonary blood flow: Evaluation using multidetector-row computed tomography","volume":"20","author":"Nabo","year":"2011","journal-title":"Heart Lung Circ."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1172\/JCI109965","article-title":"Lung growth and airway function after lobectomy in infancy for congenital lobar emphysema","volume":"66","author":"McBride","year":"1980","journal-title":"J. Clin. Investig."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/7\/9\/113\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T10:04:02Z","timestamp":1760177042000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/7\/9\/113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,28]]},"references-count":13,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2020,9]]}},"alternative-id":["children7090113"],"URL":"https:\/\/doi.org\/10.3390\/children7090113","relation":{},"ISSN":["2227-9067"],"issn-type":[{"value":"2227-9067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,28]]}}}