{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T11:24:30Z","timestamp":1768735470886,"version":"3.49.0"},"reference-count":115,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:00:00Z","timestamp":1615939200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Migraine headache is a common cause of pain and disability in children and adolescents and is a major contributor to frequently missed school days and limitations in activities. Of children and adolescents with migraine headache, approximately one-third have migraine with aura (MA). MA is often considered to be similar to migraine without aura (MO), and thus, many studies do not stratify patients based on the presence of aura. Because of this, treatment recommendations are often analogous between MA and MO, with a few notable exceptions. The purpose of this review is to highlight the current evidence demonstrating the unique pathophysiology, clinical characteristics, differential diagnosis, co-morbidities, and treatment recommendations and responses for pediatric MA.<\/jats:p>","DOI":"10.3390\/children8030228","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T05:43:26Z","timestamp":1615959806000},"page":"228","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Pediatric Episodic Migraine with Aura: A Unique Entity?"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9987-2903","authenticated-orcid":false,"given":"Hannah F.J.","family":"Shapiro","sequence":"first","affiliation":[{"name":"Department of Child Neurology, Boston Children\u2019s Hospital, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa","family":"Lebel","sequence":"additional","affiliation":[{"name":"Division of Pain Medicine, Department of Anesthesiology, Boston Children\u2019s Hospital, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1177\/0333102415573512","article-title":"Prevalence and disability of headache among Norwegian adolescents: A cross-sectional school-based study","volume":"35","author":"Krogh","year":"2015","journal-title":"Cephalalgia"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1111\/head.12810","article-title":"The Childhood and Adolescent Migraine Prevention (CHAMP) Study: A Report on Baseline Characteristics of Participants","volume":"56","author":"Powers","year":"2016","journal-title":"Headache"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Turner, S.B., Szperka, C.L., Hershey, A.D., Law, E.F., Palermo, T.M., and Groenewald, C.B. 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