{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T05:06:07Z","timestamp":1771045567586,"version":"3.50.1"},"reference-count":30,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2021,7,10]],"date-time":"2021-07-10T00:00:00Z","timestamp":1625875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Increasing numbers of children and adults with chronic disease status highlight the need for a value-based healthcare system. Patient-reported outcome measures (PROMs) are essential to value-based healthcare, yet it remains unclear how they relate to clinical outcomes such as health and daily functioning. We aimed to assess the added value of self-reported PROMs for health status (HS) and quality of life (QoL) in the long-term follow-up of children with foregut anomalies. We evaluated data of PROMs for HS and\/or QoL among eight-year-olds born with congenital diaphragmatic hernia (CDH), esophageal atresia (EA), or congenital lung malformations (CLM), collected within the infrastructure of a multidisciplinary, longitudinal follow-up program. Clinical outcomes were categorized into different outcome domains, and their relationships with self-reported HS and QoL were assessed through multivariable linear regression analyses. A total of 220 children completed HS and\/or QoL self-reports. In children with CDH and EA, lower cognition was significantly associated with lower self-reported HS. Due to the low number of cases, multivariable linear regression analysis was not possible in children with CLM. HS, QoL, and clinical outcomes represent different aspects of a child\u2019s wellbeing and should be measured simultaneously to facilitate a more holistic approach to clinical decision making.<\/jats:p>","DOI":"10.3390\/children8070587","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T00:23:36Z","timestamp":1626049416000},"page":"587","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Patient-Reported Outcome Measures and Clinical Outcomes in Children with Foregut Anomalies"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0016-7121","authenticated-orcid":false,"given":"Isabel I.","family":"Sreeram","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery and Intensive Care, Erasmus MC Sophia Children\u2019s Hospital, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9921-7776","authenticated-orcid":false,"given":"Chantal A.","family":"ten Kate","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Intensive Care, Erasmus MC Sophia Children\u2019s Hospital, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joost","family":"van Rosmalen","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Erasmus University Medical Centre, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands"},{"name":"Department of Epidemiology, Erasmus University Medical Centre, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4910-8293","authenticated-orcid":false,"given":"Johannes M.","family":"Schnater","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Intensive Care, Erasmus MC Sophia Children\u2019s Hospital, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saskia J.","family":"Gischler","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Intensive Care, Erasmus MC Sophia Children\u2019s Hospital, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9 M. H.","family":"Wijnen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Intensive Care, Erasmus MC Sophia Children\u2019s Hospital, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanneke","family":"IJsselstijn","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Intensive Care, Erasmus MC Sophia Children\u2019s Hospital, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9004-0836","authenticated-orcid":false,"given":"Andr\u00e9 B.","family":"Rietman","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Intensive Care, Erasmus MC Sophia Children\u2019s Hospital, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands"},{"name":"Department of Child and Adolescent Psychiatry\/Psychology, Erasmus MC Sophia Children\u2019s Hospital, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,7,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1136\/archdischild-2016-310716","article-title":"Chronic conditions in children and young people: Learning from administrative data","volume":"101","author":"Wijlaars","year":"2016","journal-title":"Arch. Dis. Child."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1053\/j.sempedsurg.2017.09.004","article-title":"Assessment and significance of long-term outcomes in pediatric surgery","volume":"26","author":"Ijsselstijn","year":"2017","journal-title":"Semin. Pediatr. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"The Lancet Child Adolescent Health (2018). Surviving and thriving through childhood. Lancet Child Adolesc. 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