{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T19:09:02Z","timestamp":1784142542973,"version":"3.55.0"},"reference-count":36,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,10,30]],"date-time":"2021-10-30T00:00:00Z","timestamp":1635552000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Colonic volvulus (CV) is a rare but potentially life-threatening condition with unclear etiopathogenesis. To date, less than 80 pediatric cases have been described. Hirschsprung\u2019s disease (HD) is associated with CV in 17% of cases, representing a significant risk factor. Non-HD CV is an even more complex entity. The aim of this study is to describe a series of patients with CV to accentuate some peculiar aspects of this disease. We performed a retrospective study (period: 2012\u20132021) collecting information of patients with CV. Data analyzed included: demographics, medical history, presenting symptoms and radiological and surgical details. Eleven patients (12.5 \u00b1 2.8 years; 7F\/4M) had CV (eight sigmoid, two transverse colon, one total colon). Five patients had associated anomalies and three had HD. A two-step approach with volvulus endoscopic\/radiological detorsion followed by intestinal resection was attempted in eight cases (one endoscopic approach failed). Three patients required surgery at admission. At follow-up, two patients developed recurrent intestinal obstruction, one of whom also had anastomotic stenosis. Colonic volvulus is a challenging condition that requires prompt patient care. A missed diagnosis could lead to severe complications. The evaluation of the patient should include a careful histological examination (searching for HD and alpha-actin deficiency), immunologic and metabolic screening, neurological tests and detection of chronic intestinal pseudo-obstruction (CIPO). Lifelong follow-up is mandatory for the early recognition and treatment of progressive diseases involving the proximal gastrointestinal tract.<\/jats:p>","DOI":"10.3390\/children8110982","type":"journal-article","created":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T22:21:08Z","timestamp":1635805268000},"page":"982","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Colonic Volvulus in Children: Surgical Management of a Challenging Condition"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0206-2892","authenticated-orcid":false,"given":"Francesca","family":"Destro","sequence":"first","affiliation":[{"name":"Pediatric Surgery Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano","family":"Maestri","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milena","family":"Meroni","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Campari","sequence":"additional","affiliation":[{"name":"Pediatric Radiology Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Pederiva","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Costanzo","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Del Re","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margherita","family":"Roveri","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2795-9874","authenticated-orcid":false,"given":"Gianvincenzo","family":"Zuccotti","sequence":"additional","affiliation":[{"name":"Pediatric Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"},{"name":"Department of Biomedical and Clinical Science \u201cL. Sacco\u201d, University of Milano, 20157 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2137-5974","authenticated-orcid":false,"given":"Valeria","family":"Calcaterra","sequence":"additional","affiliation":[{"name":"Pediatric Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"},{"name":"Pediatrics and Adolescentology Unit, Department of Internal Medicine, University of Pavia, 27100 Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Pelizzo","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, \u201cVittore Buzzi\u201d Children\u2019s Hospital, 20154 Milano, Italy"},{"name":"Department of Biomedical and Clinical Science \u201cL. Sacco\u201d, University of Milano, 20157 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"142","DOI":"10.5152\/eajm.2010.39","article-title":"Sigmoid volvulus","volume":"42","author":"Atamanalp","year":"2010","journal-title":"Eurasian J. 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