{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:37:42Z","timestamp":1760236662978,"version":"build-2065373602"},"reference-count":53,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:00:00Z","timestamp":1639440000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>This work presents a non-invasive methodology to obtain a three-dimensional femur model of three-year-old infants affected with Osteogenesis Imperfecta (OI) type III. DICOM\u00ae Files of a femur were processed to obtain a finite element model to assess the transverse, the oblique, and the comminuted fractures. The model is evaluated under a normal walking cycle. The loads applied were considered the most critical force generated on the normal walking cycle, and the analyses considered anisotropic bone conditions. The outcome shows stress concentration areas in the central zone of the diaphysis of the femur, and the highest levels of stress occur in the case of the comminuted fracture, while the transverse fracture presents the lowest values. Thus, the method can be helpful for determining the bone fracture behavior of certain pathologies, such as osteogenesis imperfecta, osteopenia, and osteoporosis.<\/jats:p>","DOI":"10.3390\/children8121177","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T09:34:25Z","timestamp":1639474465000},"page":"1177","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Bone Fractures Numerical Analysis in a Femur Affected by Osteogenesis Imperfecta"],"prefix":"10.3390","volume":"8","author":[{"given":"Viridiana","family":"Ram\u00edrez-Vela","sequence":"first","affiliation":[{"name":"Instituto Polit\u00e9cnico Nacional, Escuela Superior de Ingenier\u00eda Mec\u00e1nica y El\u00e9ctrica Unidad Zacatenco, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Ciudad de Mexico 07738, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7051-0001","authenticated-orcid":false,"given":"Luis Antonio","family":"Aguilar-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Instituto Polit\u00e9cnico Nacional, Escuela Superior de Ingenier\u00eda Mec\u00e1nica y El\u00e9ctrica Unidad Zacatenco, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Ciudad de Mexico 07738, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2465-6939","authenticated-orcid":false,"given":"Juan Carlos","family":"Paredes-Rojas","sequence":"additional","affiliation":[{"name":"Instituto Polit\u00e9cnico Nacional, Centro Mexicano para la Producci\u00f3n m\u00e1s Limpia, Ciudad de Mexico 07340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Alejandro","family":"Flores-Campos","sequence":"additional","affiliation":[{"name":"Instituto Polit\u00e9cnico Nacional, Unidad Profesional Interdisciplinaria en Ingenier\u00eda y Tecnolog\u00edas Avanzadas, Ciudad de Mexico 07340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando ELi","family":"Ortiz-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Instituto Polit\u00e9cnico Nacional, Escuela Superior de Ingenier\u00eda Mec\u00e1nica y El\u00e9ctrica, Unidad Culhuac\u00e1n, Ciudad de Mexico 04260, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0291-7384","authenticated-orcid":false,"given":"Christopher Ren\u00e9","family":"Torres-SanMiguel","sequence":"additional","affiliation":[{"name":"Instituto Polit\u00e9cnico Nacional, Escuela Superior de Ingenier\u00eda Mec\u00e1nica y El\u00e9ctrica Unidad Zacatenco, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Ciudad de Mexico 07738, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.pcl.2014.08.010","article-title":"Update on the Evaluation and Treatment of Osteogenesis Imperfecta","volume":"61","author":"Harrington","year":"2014","journal-title":"Pediatr. 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