{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T12:32:03Z","timestamp":1765369923326,"version":"build-2065373602"},"reference-count":19,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T00:00:00Z","timestamp":1640908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>A 17-year-old male was referred to the emergency room with sharp abdominal pain, pallor, sweating, and vomiting 12 h after the administration of his first Pfizer-BioNTech vaccine for coronavirus disease 2019 (COVID-19). He had abdominal pain, an increase in serum lipase value of &gt; 3 times the upper limits of normal, and magnetic resonance imaging (MRI) findings consistent with acute mild pancreatitis (AP). He was started on treatment with fluid therapy and non-steroidal anti-inflammatory drugs for pain management, after which he recovered rapidly and was discharged on the fourth day after hospitalization. The available data are difficult to interpret as AP is a relatively frequent disease, but its occurrence after vaccination seems extremely rare. Although it is a rare event, AP should be considered after COVID-19 vaccination, especially in those exhibiting abdominal tenderness and vomiting, which should be promptly treated and adequately investigated.<\/jats:p>","DOI":"10.3390\/children9010029","type":"journal-article","created":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T22:51:50Z","timestamp":1641250310000},"page":"29","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Acute Mild Pancreatitis Following COVID-19 mRNA Vaccine in an Adolescent"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3445-4612","authenticated-orcid":false,"given":"Ahmad","family":"Kantar","sequence":"first","affiliation":[{"name":"Paediatric Unit, Istituti Ospedalieri Bergamaschi, Gruppo Ospedaliero San Donato, 24036 Bergamo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuela","family":"Seminara","sequence":"additional","affiliation":[{"name":"Paediatric Unit, Istituti Ospedalieri Bergamaschi, Gruppo Ospedaliero San Donato, 24036 Bergamo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Odoni","sequence":"additional","affiliation":[{"name":"Paediatric Unit, Istituti Ospedalieri Bergamaschi, Gruppo Ospedaliero San Donato, 24036 Bergamo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilaria","family":"Dalla Verde","sequence":"additional","affiliation":[{"name":"Paediatric Unit, Istituti Ospedalieri Bergamaschi, Gruppo Ospedaliero San Donato, 24036 Bergamo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1126\/science.1690918","article-title":"Direct gene transfer into mouse muscle in vivo","volume":"247","author":"Wolff","year":"1990","journal-title":"Science"},{"key":"ref_2","first-page":"523","article-title":"Naturally occurring nucleoside modifications suppress the immunostimulatory activity of RNA: Im-plication for therapeutic RNA development","volume":"10","author":"Weissman","year":"2007","journal-title":"Curr. 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Nutr."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1056\/NEJMoa2034577","article-title":"Safety and efficacy of the BNT162b2 mRNA COVID-19 vaccine","volume":"383","author":"Polack","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"ref_8","unstructured":"Pfizer-BioNTech COVID-19 Vaccine (BNT162, PF-07302048) Vaccines and Related Biological Products Advisory Committee (2021, August 07). Briefing Document, Available online: https:\/\/www.fda.gov\/media\/144246\/download."},{"key":"ref_9","unstructured":"(2021, August 07). COVID-19 mRNA Pfizer-BioNTech Vaccine Analysis Print, Available online: https:\/\/assets.publishing.service.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/1009453\/COVID-19_mRNA_Pfizer-BioNTech_Vaccine_Analysis_Print_DLP_28.07.2021.pdf."},{"key":"ref_10","unstructured":"(2021, August 07). Point de Situation sur la Surveillance des Vaccins Contre la COVID-19\u2014P\u00e9riode du 9 July 2021 au 15 July 2021. 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