{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:46:07Z","timestamp":1785843967040,"version":"3.56.0"},"reference-count":20,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T00:00:00Z","timestamp":1641945600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background: Patients suffering from complete colonic aganglionosis (TCA) require the best surgical care possible. Only a few studies reported J-Pouch repair as the primary reconstructive surgery in TCA patients. This study adds to the current literature a thorough clinical and functional outcomes group. Methods: Between 2011 and 2021, medical records of Hirschsprung disease (HD) patients who underwent J-Pouch reconstruction during infancy (n = 12) were reviewed. In close follow-up, bowel function and satisfaction with operation results were evaluated. The median age at the time of J-Pouch reconstruction was 16 months, and covering ileostomies were closed four months later. There were no postoperative problems. After the final repair, Pouch-related problems (PRP) occurred in 27% of the children and were treated conservatively. There was no histological evidence of pouchitis in any of the individuals. The median 24-h stooling frequency was 4\u20135 at the latest follow-up 51 months following enterostomy closure. Conclusions: The current study\u2019s findings support the existing literature and advocate for J-pouch repair in TCA patients. However, more research will be needed to determine the best time to undergo pouch surgery and ileostomy closure in TCA patients.<\/jats:p>","DOI":"10.3390\/children9010101","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T04:15:25Z","timestamp":1641960925000},"page":"101","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Colectomy Followed by J-Pouch Reconstruction to Correct Total Colonic Aganglionosis"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7142-8758","authenticated-orcid":false,"given":"Konrad","family":"Reinshagen","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunter","family":"Burmester","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Altonaer Kinderkrankenhaus, 22763 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Hagens","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas Franz","family":"Krebs","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children\u2019s Hospital of Eastern Switzerland, 9006 St. Gallen, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9028-4163","authenticated-orcid":false,"given":"Christian","family":"Tomuschat","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,12]]},"reference":[{"key":"ref_1","first-page":"59","article-title":"One Stage Resection of Entire Colon and Rectum for Ulcerative Colitis and Polypoid Adenomatosis","volume":"88","author":"Ravitch","year":"1951","journal-title":"Bull. 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Surg."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1007\/s10350-004-6321-y","article-title":"Reconstructive Surgery for Failed Ileal Pouch-Anal Anastomosis","volume":"45","author":"MacLean","year":"2002","journal-title":"Dis. Colon Rectum"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.amjsurg.2002.12.002","article-title":"Relationship between Gastrointestinal Transit Time and Daily Stool Frequency in Patients after Ileal J Pouch-Anal Anastomosis for Ulcerative Colitis","volume":"187","author":"Tomita","year":"2004","journal-title":"Am. J. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.jpedsurg.2013.07.021","article-title":"Restorative Proctocolectomy with J-Pouch Ileoanal Anastomosis for Total Colonic Aganglionosis among Neonates and Infants","volume":"49","author":"Hukkinen","year":"2014","journal-title":"J. Pediat. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s00383-019-04440-1","article-title":"Is Fecal Diversion Necessary during Ileal Pouch Creation after Initial Subtotal Colectomy in Pediatric Ulcerative Colitis?","volume":"35","author":"Chen","year":"2019","journal-title":"Pediat. Surg. 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