{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:00:08Z","timestamp":1792623608386,"version":"4.5.0"},"reference-count":24,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,2,6]],"date-time":"2022-02-06T00:00:00Z","timestamp":1644105600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Current literature for congenital diaphragmatic hernia (CDH) focuses on the comparison of the overall mortality in CDH patients. Only a few studies concentrate on analyzing the unstable patients who could not achieve surgical repair, as well as those who could but did not survive after. Hence, this study aimed to analyze the effects of various parameters on the timing of death. A retrospective analysis was performed by using the data of all CDH patients from 2003 to 2016 at a single tertiary center. Patients who were diagnosed with left-sided CDH and expired were included in the study regardless of the cause. Of the 66 expired patients, 5 were excluded due to right-sided CDH. The study population constituted a total of 61 patients, of which 31 patients expired prior to CDH repair, and 30 patients expired at different times after CDH repair. Multinomial regression analysis identified that the ECMO need (B = 20.257, p = 0.000, OR: 62.756, 95% CI 10.600\u2013371.384) and O\/E LHR (B = 20.376, p = 0.000, OR: 70.663, 95% CI 48.716\u2013102.415) values were the independent predictors that influenced mortality in this cohort. Prenatal pulmonary measurements are the major predictors determining the severity of the disease in patients with CDH.<\/jats:p>","DOI":"10.3390\/children9020218","type":"journal-article","created":{"date-parts":[[2022,2,6]],"date-time":"2022-02-06T20:36:47Z","timestamp":1644179807000},"page":"218","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The Survivorship Bias in Congenital Diaphragmatic Hernia"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7776-9684","authenticated-orcid":false,"given":"Emrah","family":"Aydin","sequence":"first","affiliation":[{"name":"Division of Pediatric General and Thoracic Surgery, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH 45229, USA"},{"name":"Department of Pediatric Surgery, Tekirda\u011f Nam\u0131k Kemal University School of Medicine, 59030 Tekirda\u011f, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4537-7827","authenticated-orcid":false,"given":"Nilhan","family":"Torlak","sequence":"additional","affiliation":[{"name":"Cellular and Molecular Medicine, Ko\u00e7 University Graduate School of Health Sciences, 34450 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth","family":"Haberman","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Perinatal Institute, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH 45229, USA"},{"name":"College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Foong-Yen","family":"Lim","sequence":"additional","affiliation":[{"name":"Division of Pediatric General and Thoracic Surgery, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH 45229, USA"},{"name":"College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose L.","family":"Peiro","sequence":"additional","affiliation":[{"name":"Division of Pediatric General and Thoracic Surgery, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH 45229, USA"},{"name":"College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Elston, D.M. (2021). Survivorship bias. J. Am. Acad. Dermatol., 1\u20132.","DOI":"10.1016\/j.jaad.2021.06.845"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"166","DOI":"10.3322\/caac.21556","article-title":"Minimizing the burden of cancer in the United States: Goals for a high-performing health care system","volume":"69","author":"Yabroff","year":"2019","journal-title":"CA Cancer J. Clin."},{"key":"ref_3","first-page":"E45","article-title":"Uncovering survivorship bias in longitudinal mental health surveys during the COVID-19 pandemic","volume":"30","author":"Wiley","year":"2020","journal-title":"Epidemiol. Psychiatr. 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