{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:54:14Z","timestamp":1760151254656,"version":"build-2065373602"},"reference-count":6,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>In recent years, newly developed therapeutic agents have brought clinical, structural, and functional remission to many pediatric patients with rheumatic diseases that were refractory to conventional therapy. However, achieving these remissions alone is insufficient as a treatment goal, especially for adolescent patients, because advanced therapies have not always encouraged their psychosocial stability and mental maturity. Consequently, various problems have arisen during the puberty and transition period from pediatrics to adult medical care. \u201cDreams come true remission\u201d is a state of remission that allows patients to have clear dreams for the future in childhood and to increase the potential that their dreams will be realized in adulthood. This new treatment goal may empower children with chronic diseases such as PRDs to overcome the problems occurred during puberty and transition period.<\/jats:p>","DOI":"10.3390\/children9030324","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T08:17:03Z","timestamp":1646122623000},"page":"324","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Childhood Arthritis and Rheumatology Research for Dreams Come True Remission"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3905-0737","authenticated-orcid":false,"given":"Syuji","family":"Takei","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Field of Developmental Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1136\/ard.2009.123919","article-title":"Treating rheumatoid arthritis to target: Recommendations of an international task force","volume":"69","author":"Smolen","year":"2010","journal-title":"Ann. Rheum. Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1136\/annrheumdis-2013-205139","article-title":"Treat-to-garget in systemic lupus erythematosus recommendations from an international task force","volume":"73","author":"Mosca","year":"2014","journal-title":"Ann. Rheum. Dis."},{"key":"ref_3","first-page":"267","article-title":"Dreams come true remission; a new treatment goal for children with rheumatic diseases","volume":"26","author":"Takei","year":"2018","journal-title":"Inflamm. Immun."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"McDonagh, J.E., and Tattersall, R.S. (2019). Impact of rheumatic musculoskeletal disease on psychological development in adolescents and young adult. Adolescent and Young Adult Rheumatology in Clinical Practice, Springer Nature.","DOI":"10.1007\/978-3-319-95519-3"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Bitencourt, N., Bermas, B.L., Makris, U.E., Wright, T., Reisch, J., and Solow, E.B. (2020). Time to completed visit and healthcare utilization among young adults transferring from pediatric to adult rheumatologic care in a safety-net hospital. Arthritis Care Res., online ahead of print.","DOI":"10.1002\/acr.24409"},{"key":"ref_6","unstructured":"Nonaka, Y., Yamasaki, Y., Kubota, T., Nerome, Y., Imanaka, H., and Takei, S. (2021). Current status of transitional medicine for patients with pediatric rheumatic diseases in a single center. J. Clin. Pediatric Rheumatol., (In Japanese)."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/9\/3\/324\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:29:58Z","timestamp":1760135398000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/9\/3\/324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,1]]},"references-count":6,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,3]]}},"alternative-id":["children9030324"],"URL":"https:\/\/doi.org\/10.3390\/children9030324","relation":{},"ISSN":["2227-9067"],"issn-type":[{"type":"electronic","value":"2227-9067"}],"subject":[],"published":{"date-parts":[[2022,3,1]]}}}