{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T03:02:00Z","timestamp":1760151720224,"version":"build-2065373602"},"reference-count":132,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T00:00:00Z","timestamp":1648857600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Transcatheter device intervention is now offered as first line therapy for many congenital heart defects (CHD) which were traditionally treated with cardiac surgery. While off-label use of devices is common and appropriate, a growing number of devices are now specifically designed and approved for use in CHD. Advanced imaging is now an integral part of interventional procedures including pre-procedure planning, intra-procedural guidance, and post-procedure monitoring. There is robust societal and industrial support for research and development of CHD-specific devices, and the regulatory framework at the national and international level is patient friendly. It is against this backdrop that we review transcatheter implantable devices for CHD, the role and integration of advanced imaging, and explore the current regulatory framework for device approval.<\/jats:p>","DOI":"10.3390\/children9040497","type":"journal-article","created":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T02:59:52Z","timestamp":1648954792000},"page":"497","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Transcatheter Device Therapy and the Integration of Advanced Imaging in Congenital Heart Disease"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1554-6554","authenticated-orcid":false,"given":"Abhay A.","family":"Divekar","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA"},{"name":"Pediatric Cardiology, Children\u2019s Medical Center, 1935 Medical District Drive, Dallas, TX 75235, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousef M.","family":"Arar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA"},{"name":"Pediatric Cardiology, Children\u2019s Medical Center, 1935 Medical District Drive, Dallas, TX 75235, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA"},{"name":"Pediatric Cardiology, Children\u2019s Medical Center, 1935 Medical District Drive, Dallas, TX 75235, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9769-8801","authenticated-orcid":false,"given":"Animesh","family":"Tandon","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Cleveland Clinic Children\u2019s Hospital, Cleveland, OH 44195, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8159-0871","authenticated-orcid":false,"given":"Thomas M.","family":"Zellers","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA"},{"name":"Pediatric Cardiology, Children\u2019s Medical Center, 1935 Medical District Drive, Dallas, TX 75235, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0484-2902","authenticated-orcid":false,"given":"Surendranath R.","family":"Veeram Reddy","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA"},{"name":"Pediatric Cardiology, Children\u2019s Medical Center, 1935 Medical District Drive, Dallas, TX 75235, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,2]]},"reference":[{"key":"ref_1","first-page":"219","article-title":"Current Advances in Transcatheter Intervention for Children Born with Congenital Heart Defects: A Review of Literature","volume":"9","author":"Sharfi","year":"2021","journal-title":"J. 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