{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T01:05:40Z","timestamp":1772499940550,"version":"3.50.1"},"reference-count":30,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T00:00:00Z","timestamp":1648857600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background: Due to advances in the treatment of pediatric brain tumors (PBT), an increasing number of patients are experiencing the transition from the pediatric to the adult health care system. This requires efficient transitional models. Methods: We systematically reviewed the literature regarding PBT concerning different transitional models and aspects of the transitional period. For this purpose, PubMed, Medline, and Embase databases were searched systematically through January 2022. Results: We reviewed a total of 304 studies, of which 15 were ultimately included. We identified five transition models described within the literature, while the most frequently mentioned ones were the \u201cadult caregiver model\u201d (45.5%), \u201cjoint caregiver model\u201d (45.5%), \u201ccontinued caregiver model\u201d (27.3%), and the \u201cspecialized clinic model\u201d (27.3%). During the transition, the most frequent challenges mentioned by the patients were the lack of knowledge about the disease by the adult health care professionals (62.5%) and the difficulty of establishing a new relationship with the new physician, environment, or hospital (37.5%). Conclusions: An efficient transitional model is mandatory for patients with PBT. Continuity in the treatment and care of the patient and their family is essential. For this purpose, in patients with PBT, the \u201ccontinued caregiver model\u201d, and for NF1 and TSC patients, the \u201cspecialized clinic model\u201d seems optimal to offer continuity of care. If such models are unavailable, efficient communication with patients, families, and specialists in a multidisciplinary network is even more critical.<\/jats:p>","DOI":"10.3390\/children9040501","type":"journal-article","created":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T02:59:52Z","timestamp":1648954792000},"page":"501","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Transitional Care in Pediatric Brain Tumor Patients: A Systematic Literature Review"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9785-6926","authenticated-orcid":false,"given":"Florian","family":"Ebel","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospital of Basel, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ladina","family":"Greuter","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital of Basel, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael","family":"Guzman","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital of Basel, 4031 Basel, Switzerland"},{"name":"Department of Pediatric Neurosurgery, University Children\u2019s Hospital of Basel, 4056 Basel, Switzerland"},{"name":"Faculty of Medicine, University of Basel, 4056 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1900-9286","authenticated-orcid":false,"given":"Jehuda","family":"Soleman","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital of Basel, 4031 Basel, Switzerland"},{"name":"Department of Pediatric Neurosurgery, University Children\u2019s Hospital of Basel, 4056 Basel, Switzerland"},{"name":"Faculty of Medicine, University of Basel, 4056 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.ejpn.2015.07.011","article-title":"Strategies to improve the quality of survival for childhood brain tumour survivors","volume":"19","author":"Tallen","year":"2015","journal-title":"Eur. 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