{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T03:01:05Z","timestamp":1760151665529,"version":"build-2065373602"},"reference-count":19,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T00:00:00Z","timestamp":1649808000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>To date, the diagnosis of mediastinal teratoma and mediastinal masses relies on the use of chest X-ray and CT. Lung and thoracic ultrasound is becoming increasingly used in the diagnosis and follow-up of many lung and thoracic diseases. Here, we report the case of a mature cystic teratoma in which the performance of lung ultrasound allowed to speed up the diagnostic workup and to provide the indication for the execution of CT of the thorax allowing the diagnosis.<\/jats:p>","DOI":"10.3390\/children9040555","type":"journal-article","created":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T21:33:42Z","timestamp":1649885622000},"page":"555","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Key Role of Lung Ultrasound in the Diagnosis of a Mature Cystic Teratoma in a Child with Suspected Difficult to Treat Pneumonia: A Case Report"],"prefix":"10.3390","volume":"9","author":[{"given":"Elio","family":"Iovine","sequence":"first","affiliation":[{"name":"Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Petrarca","sequence":"additional","affiliation":[{"name":"Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Regina","sequence":"additional","affiliation":[{"name":"Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Matera","sequence":"additional","affiliation":[{"name":"Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrica","family":"Mancino","sequence":"additional","affiliation":[{"name":"Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greta","family":"Di Mattia","sequence":"additional","affiliation":[{"name":"Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Midulla","sequence":"additional","affiliation":[{"name":"Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8880-3462","authenticated-orcid":false,"given":"Raffaella","family":"Nenna","sequence":"additional","affiliation":[{"name":"Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1378\/chest.128.4.2893","article-title":"Tumors of the mediastinum","volume":"128","author":"Duwe","year":"2005","journal-title":"Chest"},{"key":"ref_2","unstructured":"Azizkhan, R.G. (2006). Pediatric Surgery, Mosby. [6th ed.]."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1097\/MOP.0b013e32832b41ee","article-title":"Teratomas in infants and children","volume":"21","author":"Barksdale","year":"2009","journal-title":"Curr. Opin. Pediatr."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s13244-012-0201-0","article-title":"A diagnostic approach to the mediastinal masses","volume":"4","author":"Juanpere","year":"2012","journal-title":"Insights Imaging"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1055\/a-0881-3179","article-title":"Ultrasonography of the Lung","volume":"191","author":"Radzina","year":"2019","journal-title":"R\u00f6ntgenstr"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Iovine, E., Nenna, R., Bloise, S., La Regina, D., Pepino, D., Petrarca, L., Frassanito, A., Lubrano, R., and Midulla, F. (2021). Lung Ultrasound: Its Findings and New Applications in Neonatology and Pediatric Diseases. Diagnostics, 11.","DOI":"10.3390\/diagnostics11040652"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s40477-019-00406-0","article-title":"Congenital lung malformations: A novel application for lung ultrasound?","volume":"24","author":"Merli","year":"2021","journal-title":"J. Ultrasound"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"De Rose, C., Miceli Sopo, S., Valentini, P., Morello, R., Biasucci, D., and Buonsenso, D. (2022). Potential Application of Lung Ultrasound in Children with Severe Uncontrolled Asthma: Preliminary Hypothesis Based on a Case Series. Medicines, 9.","DOI":"10.3390\/medicines9020011"},{"key":"ref_9","first-page":"68","article-title":"Mature cystic teratoma of mediastinum","volume":"16","author":"Ma","year":"2012","journal-title":"Phil. Heart Cent. J."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1002\/pbc.25423","article-title":"Mature and immature teratoma: A report from the second Italian pediatric study","volume":"62","author":"Terenziani","year":"2015","journal-title":"Pediatr. Blood Cancer"},{"key":"ref_11","first-page":"77","article-title":"A study of clinical characteristics of mediastinal mass","volume":"8","author":"Seshadri","year":"2014","journal-title":"J. Clin. Diagn. Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"323","DOI":"10.2214\/ajr.170.2.9456938","article-title":"Spontaneous rupture: A complication of benign mature teratomas of the mediastinum","volume":"170","author":"Sasaka","year":"1998","journal-title":"Am. J. Roentgenol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"105807","DOI":"10.1016\/j.ijscr.2021.105807","article-title":"Mediastinal mature teratoma with chest pain onset and subsequent perfo-ration: A case report","volume":"81","author":"Uchida","year":"2021","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"985","DOI":"10.2214\/ajr.169.4.9308448","article-title":"Mediastinal mature teratoma: Imaging features","volume":"169","author":"Moeller","year":"1997","journal-title":"Am. J. Roentgenol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"20190058","DOI":"10.1259\/bjr.20190058","article-title":"Ultrasound of the pediatric chest","volume":"92","author":"Joshi","year":"2019","journal-title":"Br. J. Radiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"33","DOI":"10.4103\/2156-7514.97750","article-title":"Imaging of Cystic and Cyst-like Lesions of the Mediastinum with Pathologic Correlation","volume":"2","author":"Nayman","year":"2012","journal-title":"J. Clin. Imaging Sci."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"e707","DOI":"10.1097\/CCM.0000000000003129","article-title":"Diagnostic Accuracy of Chest Radiograph, and When Concomitantly Studied Lung Ultrasound, in Critically Ill Patients with Respiratory Symptoms: A Systematic Review and Meta-Analysis","volume":"46","author":"Winkler","year":"2018","journal-title":"Crit. Care Med."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1007\/s00247-017-3910-1","article-title":"Lung ultrasound for the diagnosis of community-acquired pneumonia in c c children","volume":"47","author":"Stadler","year":"2017","journal-title":"Pediatr. Radiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1200\/JCO.1999.17.7.2137","article-title":"Complete Surgical Excision Is Effective Treatment for Children with Immature Teratomas with or Without Malignant Elements: A Pediatric Oncology Group\/Children\u2019s Cancer Group Intergroup Study","volume":"17","author":"Marina","year":"1999","journal-title":"J. Clin. Oncol."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/9\/4\/555\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:53:28Z","timestamp":1760136808000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/9\/4\/555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,13]]},"references-count":19,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,4]]}},"alternative-id":["children9040555"],"URL":"https:\/\/doi.org\/10.3390\/children9040555","relation":{},"ISSN":["2227-9067"],"issn-type":[{"type":"electronic","value":"2227-9067"}],"subject":[],"published":{"date-parts":[[2022,4,13]]}}}