{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:00:01Z","timestamp":1784030401117,"version":"3.55.0"},"reference-count":23,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T00:00:00Z","timestamp":1651536000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>(1) Background: Primary in-brace correction has been shown to be related to conservative adolescent idiopathic scoliosis (AIS) treatment outcome. The purpose of the study was to evaluate TLSO brace design changes over eight years regarding primary Cobb correction and de-rotation of the (major) curve. (2) Methods: This retrospective analysis included AIS patients treated with a full-time TLSO-brace in a single Orthopedic University hospital in 2012\u20132014 and 2017\u20132019. Brace design changes resulted from an evolutionary process, from a 3-point bending to a 3D TLSO. The brace parameters (presence of an anterior shoulder pad, posterior high-thoracic pad, thoracic space, and angle of the lumbar and thoracic pressure points) were analyzed regarding the primary (major) Cobb angle and apex rotation correction with a multivariate analysis. (3) Results: A total of 74 (63 female) patients were included in the study. The Cobb angle primary correction was significantly improved over the timeframe. The primary correction was significantly influenced by all design parameters and partially by its interactions with (curve specific) different effects on the Cobb correction and apex de-rotation. (4) Conclusions: Knowledge about the effects of brace design parameters on the curve\u2019s angle and rotation correction enables improvements in individualized brace design and the brace optimization process.<\/jats:p>","DOI":"10.3390\/children9050656","type":"journal-article","created":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T08:26:35Z","timestamp":1651566395000},"page":"656","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Improvement of Adolescent Idiopathic Scoliosis Primary Correction by Brace Design Optimization"],"prefix":"10.3390","volume":"9","author":[{"given":"Patrick","family":"Strube","sequence":"first","affiliation":[{"name":"Orthopedic Department, Jena University Hospital, Campus Eisenberg, Klosterlausnitzer Str. 81, 07607 Eisenberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Lindemann","sequence":"additional","affiliation":[{"name":"Orthopedic Department, Jena University Hospital, Campus Eisenberg, Klosterlausnitzer Str. 81, 07607 Eisenberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Bahrke","sequence":"additional","affiliation":[{"name":"Orthopedic Department, Jena University Hospital, Campus Eisenberg, Klosterlausnitzer Str. 81, 07607 Eisenberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Brodt","sequence":"additional","affiliation":[{"name":"Orthopedic Department, Jena University Hospital, Campus Eisenberg, Klosterlausnitzer Str. 81, 07607 Eisenberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Sachse","sequence":"additional","affiliation":[{"name":"Orthopedic Department, Jena University Hospital, Campus Eisenberg, Klosterlausnitzer Str. 81, 07607 Eisenberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lya I.","family":"Reich","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, University Hospital Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Hoelzl","sequence":"additional","affiliation":[{"name":"Orthopedic Department, Jena University Hospital, Campus Eisenberg, Klosterlausnitzer Str. 81, 07607 Eisenberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo K.","family":"Zippelius","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, University Hospital Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1056\/NEJMoa1307337","article-title":"Effects of bracing in adolescents with idiopathic scoliosis","volume":"369","author":"Weinstein","year":"2013","journal-title":"N. 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