{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:17:33Z","timestamp":1791764253519,"version":"4.3.4"},"reference-count":39,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T00:00:00Z","timestamp":1656979200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background: Root resorption (RR) of the adjacent teeth due to upper canine impaction requires an appropriate modification of the orthodontic treatment plan and the mechanotherapy used. Aim: The aim of this review was to assess scientific evidence published during the last decade, concerning the prevalence of lateral incisor RR caused by impacted maxillary canines, based only on cone-beam computed tomography (CBCT). The location of RR on this tooth, as well as the prevalence of RR on the other adjacent teeth, were additionally evaluated. Methods: This review followed the criteria specified by the PRISMA statement. Four databases were searched for articles published between January 2008 and June 2021. Predefined and piloted data collection forms were used to record the necessary information. Results: A total of 5098 records were initially screened. Only seven articles were finally eligible for further analysis. A total number of 540 participants (176 males and 364 females) was derived from the included studies. RR of maxillary lateral incisors was common (50%). RR of mild severity was more common (62%), more frequently located in the middle (52%) and apical (42%) thirds of the root. Conclusions: Further research with more homogeneous groups is required.<\/jats:p>","DOI":"10.3390\/children9071006","type":"journal-article","created":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T10:21:33Z","timestamp":1657016493000},"page":"1006","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Evaluation of Lateral Incisor Resorption Caused by Impacted Maxillary Canines Based on CBCT: A Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2833-681X","authenticated-orcid":false,"given":"Anastasia","family":"Mitsea","sequence":"first","affiliation":[{"name":"Department of Oral Diagnosis & Radiology, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Palikaraki","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Karamesinis","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heleni","family":"Vastardis","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sotiria","family":"Gizani","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9686-7423","authenticated-orcid":false,"given":"Iosif","family":"Sifakakis","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.4103\/ejd.ejd_308_16","article-title":"Frequency of impacted teeth and categorization of impacted canines: A retrospective radiographic study using orthopantomzgrams","volume":"11","author":"Alharbi","year":"2017","journal-title":"Eur. J. Dent."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1259\/dmfr\/15470658","article-title":"Incidence of canine impaction and transmigration in a patient population","volume":"33","author":"Aydin","year":"2004","journal-title":"DentoMaxilloFacial Radiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.joms.2009.09.006","article-title":"Investigation of transmigrated and impacted maxillary and mandibular canine teeth in an orthodontic patient population","volume":"68","author":"Celikoglu","year":"2010","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/ejo\/8.3.133","article-title":"Radiographic assessment of canine eruption in children with clinical signs of eruption disturbances","volume":"8","author":"Ericson","year":"1986","journal-title":"Eur. J. Orthod."},{"key":"ref_5","first-page":"332","article-title":"Incisor resorption caused by maxillary cuspids. A radiographic study","volume":"57","author":"Ericson","year":"1987","journal-title":"Angle Orthod."},{"key":"ref_6","first-page":"65","article-title":"Prevalence of impacted permanent upper canine and its treatment in 11-18-year-old orthodontic patients","volume":"96","year":"2003","journal-title":"Fogorv. Sz."},{"key":"ref_7","first-page":"ZE11","article-title":"Localization of impacted canines","volume":"9","author":"Kumar","year":"2015","journal-title":"J. Clin. Diagn. Res."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/0030-4220(85)90070-2","article-title":"The incidence of unerupted permanent teeth and related clinical cases","volume":"59","author":"Grover","year":"1985","journal-title":"Oral Surg. Oral Med. Oral Pathol."},{"key":"ref_9","first-page":"265","article-title":"Studies of permanent tooth anomalies in 7886 Canadian individuals. II: Congenitally missing, supernumerary and peg teeth","volume":"44","author":"Shah","year":"1978","journal-title":"Dent. J."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0889-5406(92)70008-X","article-title":"Impacted maxillary canines: A review","volume":"101","author":"Bishara","year":"1992","journal-title":"Am. J. Orthod. Dentofacial. Orthop."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s40368-021-00650-1","article-title":"Eruption pattern of the maxillary canines: Features of natural eruption seen in PTG at the late mixed stage-Part I","volume":"23","author":"Ristaniemi","year":"2022","journal-title":"Eur. Arch. Paediatr. Dent."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"56","DOI":"10.25122\/jml-2020-0001","article-title":"Localization of Impacted Canines\u2014A Comparative Study of Computed Tomography and Orthopantomography","volume":"13","author":"Mohammed","year":"2020","journal-title":"J. Med. Life."},{"key":"ref_13","first-page":"249","article-title":"The palatally displaced canine as a dental anomaly of genetic origin","volume":"64","author":"Peck","year":"1994","journal-title":"Angle Orthod."},{"key":"ref_14","first-page":"415","article-title":"Resorption of incisors after ectopic eruption of maxillary canines: A CT study","volume":"70","author":"Ericson","year":"2000","journal-title":"Angle Orthod."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s00784-009-0262-8","article-title":"Root resorption of the maxillary lateral incisor caused by impacted canine: A literature review","volume":"13","author":"Alqerban","year":"2009","journal-title":"Clin. Oral Investig."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/0889-5406(88)90008-X","article-title":"Resorption of maxillary lateral incisors caused by ectopic eruption of the canines. A clinical and radiographic analysis of predisposing factors","volume":"94","author":"Ericson","year":"1988","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_17","first-page":"95","article-title":"Does the canine dental follicle cause resorption of permanent incisor roots? A computed tomographic study of erupting maxillary canines","volume":"72","author":"Ericson","year":"2002","journal-title":"Angle Orthod."},{"key":"ref_18","first-page":"743","article-title":"Impacted maxillary canines and root resorption of adjacent teeth: A retrospective observational study","volume":"21","author":"Guarnieri","year":"2016","journal-title":"Med. Oral Patol. Oral"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1259\/dmfr\/65487937","article-title":"Conventional and digital radiographic methods in detection of simulated external root resorptions: A comparative study","volume":"33","author":"Westphalen","year":"2004","journal-title":"Dentomaxillofac. Radiol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.ajodo.2017.06.026","article-title":"Reliability of different radiographic methods for the localization of displaced maxillary canines","volume":"153","author":"Tsolakis","year":"2018","journal-title":"Am. J. Orthod. Dentofacial. Orthop."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"b2700","DOI":"10.1136\/bmj.b2700","article-title":"The PRISMA statement for reporting systematic reviews and meta- analyses of studies that evaluate healthcare interventions: Explanation and elaboration","volume":"339","author":"Liberati","year":"2009","journal-title":"BMJ"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"i4919","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: A tool for assessing risk of bias in a non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin. Trials"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/2049-3258-72-39","article-title":"Metaprop: A Stata command to perform meta-analysis of binomial data","volume":"72","author":"Nyaga","year":"2014","journal-title":"Arch. Public Health"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"6635575","DOI":"10.1155\/2021\/6635575","article-title":"Root Resorption of Teeth Adjacent to Untreated Impacted Maxillary Canines: A CBCT Study","volume":"2021","author":"Ali","year":"2021","journal-title":"Biomed. Res. Int."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/ejo\/cjy078","article-title":"Prevalence and risk factors of root resorption of adjacent teeth in maxillary canine impaction, among untreated children and adolescents","volume":"41","author":"Rafflenbeul","year":"2019","journal-title":"Eur. J. Orthod."},{"key":"ref_28","first-page":"49","article-title":"Location and severity of root resorption related to impacted maxillary canines: A cone beam computed tomography (CBCT) evaluation","volume":"31","author":"Sherriff","year":"2015","journal-title":"Aust. Orthod. J."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"609","DOI":"10.3109\/00016357.2015.1020339","article-title":"Root resorptions related to ectopic and normal eruption of maxillary canine teeth\u2014A 3D study","volume":"73","author":"Pirttiniemi","year":"2015","journal-title":"Acta Odontol. Scand."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/ejo\/cjs037","article-title":"Impacted maxillary canines and root resorptions of neighbouring teeth: A radiographic analysis using cone-beam computed tomography","volume":"35","author":"Lai","year":"2013","journal-title":"Eur. J. Orthod."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.tripleo.2007.01.030","article-title":"Localization of impacted maxillary canines and observation of adjacent incisor resorption with cone-beam computed tomography","volume":"105","author":"Liu","year":"2008","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.tripleo.2011.03.035","article-title":"Three-dimensional assessment of impacted canines and root resorption using cone beam computed tomography","volume":"113","author":"Oberoi","year":"2012","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.adaj.2018.05.012","article-title":"To what extent are impacted canines associated with root resorption of the adjacent tooth?: A systematic review with meta-analysis","volume":"149","author":"Schroder","year":"2018","journal-title":"J. Am. Dent. Assoc."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.ejmp.2015.09.004","article-title":"Dental cone beam CT: A review","volume":"31","author":"Kiljunen","year":"2015","journal-title":"Phys. Med."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"e129","DOI":"10.1016\/j.ajodo.2011.03.021","article-title":"Comparison of 6 cone-beam computed tomography systems for image quality and detection of simulated canine impaction-induced external root resorption in maxillary lateral incisors","volume":"140","author":"Alqerban","year":"2011","journal-title":"Am. J. Orthod. Dentofacial Orthop."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"878","DOI":"10.2319\/021417-105.1","article-title":"Extraction of primary canines for interceptive orthodontic treatment of palatally displaced permanent canines: A systematic review","volume":"87","author":"Almasoud","year":"2017","journal-title":"Angle Orthod."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.ajodo.2009.03.036","article-title":"In-vitro comparison of 2 cone-beam computed tomography systems and panoramic imaging for detecting simulated canine impaction-induced external root resorption in maxillary lateral incisors","volume":"136","author":"Alqerban","year":"2009","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/ejo\/cjy027","article-title":"Evaluation of orthodontically induced external root resorption following orthodontic treatment using cone beam computed tomography (CBCT): A systematic review and meta-analysis","volume":"41","author":"Samandara","year":"2018","journal-title":"Eur. J. Orthod."},{"key":"ref_39","first-page":"59","article-title":"Standard and low-dose cone beam computer tomography protocol for orthognatodontic diagnosis: A comparative evaluation","volume":"32","author":"Portelli","year":"2018","journal-title":"J. Biol. Regul. Homeostatic. Agents."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/9\/7\/1006\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:42:49Z","timestamp":1760139769000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/9\/7\/1006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,5]]},"references-count":39,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2022,7]]}},"alternative-id":["children9071006"],"URL":"https:\/\/doi.org\/10.3390\/children9071006","relation":{},"ISSN":["2227-9067"],"issn-type":[{"value":"2227-9067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,5]]}}}