{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:04:40Z","timestamp":1792803880464,"version":"4.5.0"},"reference-count":222,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T00:00:00Z","timestamp":1657411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"\u00abPersonenfoerderung\u00bb Program of the Department of Surgery at the University Hospital Basel","award":["No. 842043 [CatchGel]"],"award-info":[{"award-number":["No. 842043 [CatchGel]"]}]},{"name":"Research Fund for Junior Researchers at the University of Basel","award":["No. 842043 [CatchGel]"],"award-info":[{"award-number":["No. 842043 [CatchGel]"]}],"id":[{"id":"https:\/\/ror.org\/02s6k3f65","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Z. Walsh-Korb acknowledges financial support from the European Union\u2019s Horizon 2020 research and innovation programme under the Marie Sk\u0142odowska-Curie","award":["No. 842043 [CatchGel]"],"award-info":[{"award-number":["No. 842043 [CatchGel]"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Short bowel syndrome (SBS) is a devastating disorder with both short- and long-term implications for patients. Unfortunately, the prevalence of SBS has doubled over the past 40 years. Broadly speaking, the etiology of SBS can be categorized as congenital or secondary, the latter typically due to extensive small bowel resection following diseases of the small intestine, e.g., necrotizing enterocolitis, Hirschsprung\u2019s disease or intestinal atresia. As of yet, no cure exists, thus, conservative treatment, primarily parenteral nutrition (PN), is the first-line therapy. In some cases, weaning from PN is not possible and operative therapy is required. The invention of the longitudinal intestinal lengthening and tailoring (LILT or Bianchi) procedure in 1980 was a major step forward in patient care and spawned further techniques that continue to improve lives for patients with severe SBS (e.g., double barrel enteroplasty, serial transverse enteroplasty, etc.). With this review, we aim to provide an overview of the clinical implications of SBS, common conservative therapies and the development of operative techniques over the past six decades. We also provide a short outlook on the future of operative techniques, specifically with respect to regenerative medicine.<\/jats:p>","DOI":"10.3390\/children9071024","type":"journal-article","created":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T21:19:28Z","timestamp":1657487968000},"page":"1024","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Surgical Treatment of Short Bowel Syndrome\u2014The Past, the Present and the Future, a Descriptive Review of the Literature"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2032-7863","authenticated-orcid":false,"given":"Julian L.","family":"Muff","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, Children\u2019s University Hospital, 4056 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2500-8597","authenticated-orcid":false,"given":"Filipp","family":"Sokolovski","sequence":"additional","affiliation":[{"name":"Department of General and Visceral Surgery, Kepler University Hospital, 4020 Linz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zarah","family":"Walsh-Korb","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Basel, 4058 Basel, Switzerland"},{"name":"Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashikh A.","family":"Choudhury","sequence":"additional","affiliation":[{"name":"Department of Transplant Surgery, University of Colorado Hospital, Aurora, CO 80045, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6826-7065","authenticated-orcid":false,"given":"James C. Y.","family":"Dunn","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Stanford University School of Medicine, Stanford, CA 94304, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1358-3439","authenticated-orcid":false,"given":"Stefan G.","family":"Holland-Cunz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children\u2019s University Hospital, 4056 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael N.","family":"Vuille-dit-Bille","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children\u2019s University Hospital, 4056 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/MPG.0000000000001722","article-title":"Intestinal Rehabilitation Programs in the Management of Pediatric Intestinal Failure and Short Bowel Syndrome","volume":"65","author":"Merritt","year":"2017","journal-title":"J. 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