{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:37:31Z","timestamp":1787027851504,"version":"build-2736575974"},"reference-count":81,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T00:00:00Z","timestamp":1657756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>An estimated one in six children in the United States suffers from a mental disorder, including mood, anxiety, or behavioral disorders. This rate is even higher in children with chronic medical illness. This manuscript provides a concise review of the symptoms that comprise mental conditions often observed in children with chronic illness or at the end of life. It further provides some guidance to help clinicians distinguish normative from pathological presentations. Evidence-based psychotherapy interventions, potentially applicable to the acute inpatient setting, are briefly summarized. Broad recommendations are made regarding both psychotherapeutic as well as pharmacotherapeutic interventions, with a review of common or serious medication side effects. Finally, delirium recognition and management are summarized.<\/jats:p>","DOI":"10.3390\/children9071051","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:17:10Z","timestamp":1657844230000},"page":"1051","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Psychological and Psychiatric Comorbidities in Youth with Serious Physical Illness"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8923-4943","authenticated-orcid":false,"given":"Sohail","family":"Nibras","sequence":"first","affiliation":[{"name":"Menninger Department of Psychiatry and Behavioral Sciences and Department of Pediatrics, Baylor College of Medicine, 1 Moursund St, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5287-6253","authenticated-orcid":false,"given":"Rachel","family":"Kentor","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, (Primary) Texas Children\u2019s Hospital, Psychology Service, Baylor College of Medicine, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasir","family":"Masood","sequence":"additional","affiliation":[{"name":"Department of Public Health, Brown School, Washington University in Saint Louis, One Brookings Drive, St. Louis, MO 63130, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Price","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, (Primary) Texas Children\u2019s Hospital, Psychology Service, Baylor College of Medicine, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole M.","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, (Primary) Texas Children\u2019s Hospital, Psychology Service, Baylor College of Medicine, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel B.","family":"Tenenbaum","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, (Primary) Texas Children\u2019s Hospital, Psychology Service, Baylor College of Medicine, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chadi","family":"Calarge","sequence":"additional","affiliation":[{"name":"Menninger Department of Psychiatry and Behavioral Sciences and Department of Pediatrics, Baylor College of Medicine, 1 Moursund St, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.15585\/mmwr.mm6750a1","article-title":"Health care, family, and community factors associated with mental, behavioral, and developmental disorders and poverty among children aged 2\u20138 years\u2014United States, 2016","volume":"67","author":"Cree","year":"2018","journal-title":"Morb. 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