{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T06:41:04Z","timestamp":1792219264737,"version":"4.4.0"},"reference-count":40,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T00:00:00Z","timestamp":1670457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>(1) Background: Cerebral palsy (CP) is associated with a higher incidence of epileptic seizures. This study uses a prediction model to identify the factors associated with epilepsy in children with CP. (2) Methods: This is a retrospective longitudinal study of the clinical characteristics of 102 children with CP. In the study, there were 58 males and 44 females, 65 inpatients and 37 outpatients, 72 had epilepsy, and 22 had intractable epilepsy. The mean age was 16.6 \u00b1 1.2 years, and the age range for this study was 12\u201318 years. Data were collected on the CP etiology, diagnosis, type of epilepsy and spasticity, clinical history, communication abilities, behaviors, intellectual disability, motor function, and feeding abilities from 2005 to 2020. A prediction model, Epi-PredictMed, was implemented to forecast the factors associated with epilepsy. We used the guidelines of \u201cTransparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis\u201d (TRIPOD). (3) Results: CP etiology [(prenatal &gt; perinatal &gt; postnatal causes) p = 0.036], scoliosis (p = 0.048), communication (p = 0.018), feeding disorders (p = 0.002), poor motor function (p &lt; 0.001), intellectual disabilities (p = 0.007), and the type of spasticity [(quadriplegia\/triplegia &gt; diplegia &gt; hemiplegia), p = 0.002)] were associated with having epilepsy. The model scored an average of 82% for accuracy, sensitivity, and specificity. (4) Conclusion: Prenatal CP etiology, spasticity, scoliosis, severe intellectual disabilities, poor motor skills, and communication and feeding disorders were associated with epilepsy in children with CP. To implement preventive and\/or management measures, caregivers and families of children with CP and epilepsy should be aware of the likelihood that these children will develop these conditions.<\/jats:p>","DOI":"10.3390\/children9121918","type":"journal-article","created":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T01:44:31Z","timestamp":1670463871000},"page":"1918","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prediction Model for Identifying Factors Associated with Epilepsy in Children with Cerebral Palsy"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9689-0209","authenticated-orcid":false,"given":"Carlo Mario","family":"Bertoncelli","sequence":"first","affiliation":[{"name":"Department of Computer Science, Hal Marcus College of Science & Engineering, University of West Florida, Pensacola, FL 32514, USA"},{"name":"EEAP H Germain & Department of Pediatric Orthopaedic Surgery, Lenval University Pediatric Hospital of Nice, 06200 Nice, France"},{"name":"Department of Information Engineering Computer Science and Mathematics, University of L\u2019Aquila, 67100 L\u2019Aquila, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Dehan","sequence":"additional","affiliation":[{"name":"Lenval University Pediatric Hospital of Nice, 06200 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Bertoncelli","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Hal Marcus College of Science & Engineering, University of West Florida, Pensacola, FL 32514, USA"},{"name":"Department of Information Engineering Computer Science and Mathematics, University of L\u2019Aquila, 67100 L\u2019Aquila, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sikha","family":"Bagui","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Hal Marcus College of Science & Engineering, University of West Florida, Pensacola, FL 32514, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1886-4582","authenticated-orcid":false,"given":"Subhash C.","family":"Bagui","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Hal Marcus College of Science & Engineering, University of West Florida, Pensacola, FL 32514, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Costantini","sequence":"additional","affiliation":[{"name":"Department of Information Engineering Computer Science and Mathematics, University of L\u2019Aquila, 67100 L\u2019Aquila, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2735-5330","authenticated-orcid":false,"given":"Federico","family":"Solla","sequence":"additional","affiliation":[{"name":"EEAP H Germain & Department of Pediatric Orthopaedic Surgery, Lenval University Pediatric Hospital of Nice, 06200 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1017\/S001216220500112X","article-title":"Proposed definition and classification of cerebral palsy","volume":"47","author":"Bax","year":"2005","journal-title":"Dev. 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