{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T01:15:08Z","timestamp":1780362908963,"version":"3.54.1"},"reference-count":40,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T00:00:00Z","timestamp":1670457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Italian Ministry of Health\u2014Ricerca Corrente RC 2021","award":["2763769"],"award-info":[{"award-number":["2763769"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Dramatic events during the COVID-19 pandemic have acutely impacted the psychosocial environment worldwide, with negative implications for mental health, particularly for more vulnerable children and adolescents with severe psychiatric illnesses. Some data suggest that the pandemic waves may have produced different psychopathological consequences, further worsening in the second phase of the pandemic, compared to those in the first lockdown, soon after March 2020. To test the hypothesis of a further worsening of psychiatric consequences of COVID-19 in the second lockdown compared to the first lockdown, we focused our analysis on a consecutive sample of youth referred to a psychiatric emergency unit for acute mental disorders in the time period between March 2019\u2013March 2021. The sample, consisting of 241 subjects (123 males and 118 females, ranging in age from 11 to 17 years), was divided into three groups: Pre-Lockdown Group (PLG, 115 patients); First Lockdown Group (FLG, 65 patients); and Second Lockdown Group (SLG, 61 patients). Patients in the SLG presented more frequently with non-suicidal self-injuries (NSSIs), suicidal ideation, and suicidal behavior, while no significant differences in self-harm were found between PLG and FLG. Eating disorders were more frequent in both the FLG and SLG, compared to the PLG, while sleep problems were higher only in the SLG. Furthermore, patients in the SLG presented with more frequent psychological maltreatments and neglect, as well as with psychiatric disorders in the parents. Adverse traumatic experiences and internalizing disorders were significantly associated with an increased risk of suicidality. Intellectual disability was less represented from the PLG to SLG, and similarly, the rate of ADHD was lower in the SLG. No differences were found for the other psychiatric diagnoses. This information may be helpful for a better understanding and management of adolescents with severe emotional and behavioral disorders after the exposure to long-lasting collective traumas.<\/jats:p>","DOI":"10.3390\/children9121921","type":"journal-article","created":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T01:44:31Z","timestamp":1670463871000},"page":"1921","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["How COVID-19 Phases Have Impacted Psychiatric Risk: A Retrospective Study in an Emergency Care Unit for Adolescents"],"prefix":"10.3390","volume":"9","author":[{"given":"Maria","family":"Mucci","sequence":"first","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Lenzi","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia Maria","family":"D'Acunto","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa","family":"Gazzillo","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilaria","family":"Accorinti","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Boldrini","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Distefano","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Falcone","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Fossati","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Giurdanella Annina","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Paese","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Salluce","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Troiano","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinzia","family":"Fratoni","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Fabiani","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Liboni","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7770-926X","authenticated-orcid":false,"given":"Gabriele","family":"Masi","sequence":"additional","affiliation":[{"name":"IRCCS Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, 56025 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"n1730","DOI":"10.1136\/bmj.n1730","article-title":"Mental health and wellbeing of children and adolescents during the COVID-19 pandemic","volume":"374","author":"Rider","year":"2021","journal-title":"BMJ"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s11920-022-01313-8","article-title":"Emotional and Behavioral Impact of the COVID-19 Epidemic in Adolescents","volume":"24","author":"Bera","year":"2022","journal-title":"Curr. 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