{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T16:27:26Z","timestamp":1774369646845,"version":"3.50.1"},"reference-count":187,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,12,10]],"date-time":"2022-12-10T00:00:00Z","timestamp":1670630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Vision is an important aspect of a child\u2019s quality of life and intellectual, social, and emotional development. Disruptions to vision during infancy and early childhood can cause lifelong vision impairment or blindness. However, early identification and treatment of eye disease can prevent loss of sight and its consequent long-term effects. Therefore, screening guidelines exist to guide physicians in detecting the most common threats to sight in the different stages of infancy and childhood. This review describes common causes of pediatric vision impairment, the recommended screening guidelines for diagnosing them, and current treatment modalities.<\/jats:p>","DOI":"10.3390\/children9121939","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T02:15:33Z","timestamp":1670811333000},"page":"1939","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Screening, Diagnosis, and Treatment of Pediatric Ocular Diseases"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8556-5251","authenticated-orcid":false,"given":"Matthew","family":"Lam","sequence":"first","affiliation":[{"name":"Creighton University School of Medicine Phoenix Regional Campus, Phoenix, AZ 85012, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0348-2060","authenticated-orcid":false,"given":"Donny","family":"Suh","sequence":"additional","affiliation":[{"name":"Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA 92697, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,10]]},"reference":[{"key":"ref_1","first-page":"227","article-title":"Childhood blindness in the context of VISION 2020\u2014The right to sight","volume":"79","author":"Gilbert","year":"2001","journal-title":"Bull. World Health Organ."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e489","DOI":"10.1016\/S2214-109X(20)30488-5","article-title":"The Lancet Global Health Commission on Global Eye Health: Vision beyond 2020","volume":"9","author":"Burton","year":"2021","journal-title":"Lancet Glob. Health"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1111\/j.1469-7610.2009.02200.x","article-title":"Are language and social communication intact in children with congenital visual impairment at school age?","volume":"51","author":"Tadic","year":"2010","journal-title":"J. Child Psychol. Psychiatry"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1111\/j.1469-8749.2002.tb00287.x","article-title":"Visual impairment in infancy: Impact on neurodevelopmental and neurobiological processes","volume":"44","author":"Sonksen","year":"2002","journal-title":"Dev. Med. Child Neurol."},{"key":"ref_5","unstructured":"Wilson, J.M.G., and Jungner, G. (1968). Principles and Practice of Screening for Disease, World Health Organization."},{"key":"ref_6","first-page":"907","article-title":"The eye in childhood","volume":"60","author":"Mills","year":"1999","journal-title":"Am. Fam. Physician"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3109\/01658107.2015.1055363","article-title":"Pupillary Size and Light Reflex in Premature Infants","volume":"39","author":"Ikeda","year":"2015","journal-title":"Neuroophthalmology"},{"key":"ref_8","unstructured":"Augustyn, M., Parker, S., and Zuckerman, B.S. (2010). Developmental and Behavioral Pediatrics: A Handbook for Primary Care, Lippincott Williams and Wilkins."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1542\/peds.2013-3820","article-title":"Referral to pediatric surgical specialists","volume":"133","author":"Klein","year":"2014","journal-title":"Pediatrics"},{"key":"ref_10","first-page":"28","article-title":"Visual System Assessment in Infants, Children, and Young Adults by Pediatricians","volume":"137","author":"Donahue","year":"2016","journal-title":"Pediatrics"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"P184","DOI":"10.1016\/j.ophtha.2017.09.032","article-title":"Pediatric Eye Evaluations Preferred Practice Pattern(R): I. Vision Screening in the Primary Care and Community Setting; II. Comprehensive Ophthalmic Examination","volume":"125","author":"Wallace","year":"2018","journal-title":"Ophthalmology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0161-6420(89)32932-0","article-title":"Strabismus in infancy","volume":"96","author":"Archer","year":"1989","journal-title":"Ophthalmology"},{"key":"ref_13","unstructured":"Graham, C.H. (1965). Visual Acuity. Vision and Visual Perception, Wiley."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1146\/annurev.ne.08.030185.002431","article-title":"Postnatal development of vision in human and nonhuman primates","volume":"8","author":"Boothe","year":"1985","journal-title":"Annu. Rev. Neurosci."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"e20153597","DOI":"10.1542\/peds.2015-3597","article-title":"Procedures for the Evaluation of the Visual System by Pediatricians","volume":"137","author":"Donahue","year":"2016","journal-title":"Pediatrics"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1001\/jama.2017.11260","article-title":"Vision Screening in Children Aged 6 Months to 5 Years: US Preventive Services Task Force Recommendation Statement","volume":"318","author":"Force","year":"2017","journal-title":"JAMA"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1001\/archophthalmol.2011.179","article-title":"Effect of age on response to amblyopia treatment in children","volume":"129","author":"Holmes","year":"2011","journal-title":"Arch. Ophthalmol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1053\/j.semperi.2019.05.001","article-title":"Retinopathy of prematurity\u2014A world update","volume":"43","author":"Darlow","year":"2019","journal-title":"Semin Perinatol"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/S0022-3476(46)80009-X","article-title":"Retrolental fibroplasia","volume":"29","author":"Terry","year":"1946","journal-title":"J Pediatr"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/pr.2013.205","article-title":"Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010","volume":"74","author":"Blencowe","year":"2013","journal-title":"Pediatr Res."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1001\/archophthalmol.2012.2357","article-title":"Swedish national register for retinopathy of prematurity (SWEDROP) and the evaluation of screening in Sweden","volume":"130","author":"Holmstrom","year":"2012","journal-title":"Arch. Ophthalmol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/S0140-6736(13)60178-6","article-title":"Retinopathy of prematurity","volume":"382","author":"Hellstrom","year":"2013","journal-title":"Lancet"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"553","DOI":"10.3928\/23258160-20170630-06","article-title":"The Epidemiology of Retinopathy of Prematurity in the United States","volume":"48","author":"Ludwig","year":"2017","journal-title":"Ophthalmic. Surg. Lasers Imaging Retina"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1001\/archophthalmol.2009.244","article-title":"Incidence of retinopathy of prematurity in infants born before 27 weeks\u2019 gestation in Sweden","volume":"127","author":"Austeng","year":"2009","journal-title":"Arch. Ophthalmol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.ophtha.2014.07.050","article-title":"Pathophysiology and mechanisms of severe retinopathy of prematurity","volume":"122","author":"Hartnett","year":"2015","journal-title":"Ophthalmology"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"e20183061","DOI":"10.1542\/peds.2018-3061","article-title":"Screening Examination of Premature Infants for Retinopathy of Prematurity","volume":"142","author":"Fierson","year":"2018","journal-title":"Pediatrics"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1001\/archopht.120.11.1470","article-title":"Evidence-based screening criteria for retinopathy of prematurity: Natural history data from the CRYO-ROP and LIGHT-ROP studies","volume":"120","author":"Reynolds","year":"2002","journal-title":"Arch. Ophthalmol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1056\/NEJM199805283382202","article-title":"Lack of efficacy of light reduction in preventing retinopathy of prematurity. Light Reduction in Retinopathy of Prematurity (LIGHT-ROP) Cooperative Group","volume":"338","author":"Reynolds","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1001\/archopht.116.5.608","article-title":"Timing of initial screening examinations for retinopathy of prematurity","volume":"116","author":"Hutchinson","year":"1998","journal-title":"Arch. Ophthalmol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/S0161-6420(91)32074-8","article-title":"Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group","volume":"98","author":"Palmer","year":"1991","journal-title":"Ophthalmology"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"International Committee for the Classification of Retinopathy of Prematurity (2005). The International Classification of Retinopathy of Prematurity revisited. Arch. Ophthalmol., 123, 991\u2013999.","DOI":"10.1001\/archopht.123.7.991"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1001\/archopht.118.5.645","article-title":"Involution of retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group","volume":"118","author":"Repka","year":"2000","journal-title":"Arch. Ophthalmol."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Multicenter trial of cryotherapy for retinopathy of prematurity (1990). Three-month outcome. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch. Ophthalmol., 108, 195\u2013204.","DOI":"10.1001\/archopht.1990.01070040047029"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Early Treatment for Retinopathy of Prematurity Cooperative Group (2003). Revised indications for the treatment of retinopathy of prematurity: Results of the early treatment for retinopathy of prematurity randomized trial. Arch. Ophthalmol., 121, 1684\u20131694.","DOI":"10.1001\/archopht.121.12.1684"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1016\/S0140-6736(19)31344-3","article-title":"Ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW): An open-label randomised controlled trial","volume":"394","author":"Stahl","year":"2019","journal-title":"Lancet"},{"key":"ref_36","first-page":"CD009734","article-title":"Anti-vascular endothelial growth factor (VEGF) drugs for treatment of retinopathy of prematurity","volume":"1","author":"Sankar","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1056\/NEJMoa1007374","article-title":"Efficacy of intravitreal bevacizumab for stage 3+ retinopathy of prematurity","volume":"364","author":"Kennedy","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/S0161-6420(91)32247-4","article-title":"Laser photocoagulation for stage 3+ retinopathy of prematurity","volume":"98","author":"McNamara","year":"1991","journal-title":"Ophthalmology"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S1091-8531(99)70008-X","article-title":"Therapeutic outcomes of cryotherapy versus transpupillary diode laser photocoagulation for threshold retinopathy of prematurity","volume":"3","author":"Paysse","year":"1999","journal-title":"J. AAPOS"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1001\/jamaophthalmol.2014.2772","article-title":"Refractive outcomes following bevacizumab monotherapy compared with conventional laser treatment: A randomized clinical trial","volume":"132","author":"Geloneck","year":"2014","journal-title":"JAMA Ophthalmol."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Li, Z., Zhang, Y., Liao, Y., Zeng, R., Zeng, P., and Lan, Y. (2018). Comparison of efficacy between anti-vascular endothelial growth factor (VEGF) and laser treatment in Type-1 and threshold retinopathy of prematurity (ROP). BMC Ophthalmol., 18.","DOI":"10.1186\/s12886-018-0685-6"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1001\/jama.2022.10564","article-title":"Effect of Intravitreal Aflibercept vs Laser Photocoagulation on Treatment Success of Retinopathy of Prematurity: The FIREFLEYE Randomized Clinical Trial","volume":"328","author":"Stahl","year":"2022","journal-title":"JAMA"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/S0161-6420(01)01017-X","article-title":"A comparison of laser photocoagulation with cryotherapy for threshold retinopathy of prematurity at 10 years: Part 1. Visual function and structural outcome","volume":"109","author":"Ng","year":"2002","journal-title":"Ophthalmology"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/S0161-6420(01)01015-6","article-title":"A comparison of laser photocoagulation with cryotherapy for threshold retinopathy of prematurity at 10 years: Part 2. Refractive outcome","volume":"109","author":"Connolly","year":"2002","journal-title":"Ophthalmology"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"412","DOI":"10.3109\/0284186X.2015.1099732","article-title":"Danish retinoblastoma patients 1943\u20132013\u2014genetic testing and clinical implications","volume":"55","author":"Gregersen","year":"2016","journal-title":"Acta Oncol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1016\/j.ophtha.2003.10.023","article-title":"Incidence of retinoblastoma from 1958 to 1998 in Northern Europe: Advantages of birth cohort analysis","volume":"111","author":"Seregard","year":"2004","journal-title":"Ophthalmology"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1136\/bjo.2008.138750","article-title":"Incidence of retinoblastoma in the USA: 1975-2004","volume":"93","author":"Broaddus","year":"2009","journal-title":"Br. J. Ophthalmol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1097\/00006982-200412000-00002","article-title":"Update on retinoblastoma","volume":"24","author":"Abramson","year":"2004","journal-title":"Retina"},{"key":"ref_49","unstructured":"PDQ Pediatric Treatment Editorial Board (2022). Retinoblastoma Treatment (PDQ\u00ae): Health Professional Version. PDQ Cancer Information Summaries, National Cancer Institute (US)."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"182","DOI":"10.3928\/01913913-20171116-03","article-title":"Retinoblastoma in the United States: A 40-Year Incidence and Survival Analysis","volume":"55","author":"Fernandes","year":"2018","journal-title":"J. Pediatr. Ophthalmol. Strabismus"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1136\/bjo.2008.139626","article-title":"Retinoblastoma: Treatment and survival in Great Britain 1963 to 2002","volume":"93","author":"MacCarthy","year":"2009","journal-title":"Br. J. Ophthalmol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.ajo.2015.07.037","article-title":"Retinoblastoma: A SEER Dataset Evaluation for Treatment Patterns, Survival, and Second Malignant Neoplasms","volume":"160","author":"Tamboli","year":"2015","journal-title":"Am. J. Ophthalmol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1136\/bjo.2008.143842","article-title":"Survival with retinoblastoma in the USA: 1975\u20132004","volume":"93","author":"Broaddus","year":"2009","journal-title":"Br. J. Ophthalmol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1001\/jamaoncol.2019.6716","article-title":"Global Retinoblastoma Presentation and Analysis by National Income Level","volume":"6","author":"Fabian","year":"2020","journal-title":"JAMA Oncol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"15021","DOI":"10.1038\/nrdp.2015.21","article-title":"Retinoblastoma","volume":"1","author":"Dimaras","year":"2015","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1542\/peds.112.6.1248","article-title":"Screening for retinoblastoma: Presenting signs as prognosticators of patient and ocular survival","volume":"112","author":"Abramson","year":"2003","journal-title":"Pediatrics"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.ophtha.2017.09.001","article-title":"Screening Children at Risk for Retinoblastoma: Consensus Report from the American Association of Ophthalmic Oncologists and Pathologists","volume":"125","author":"Skalet","year":"2018","journal-title":"Ophthalmology"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"387","DOI":"10.3928\/0090-4481-19900601-08","article-title":"Retinoblastoma 1990: Diagnosis, treatment, and implications","volume":"19","author":"Abramson","year":"1990","journal-title":"Pediatr. Ann."},{"key":"ref_59","unstructured":"Pizzo, P.A., and Poplack, D.G. (2011). Principles and Practice of Pediatric Oncology, Lippincott Williams & Wilkins. [6th ed.]."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.ajo.2009.04.004","article-title":"Frontiers in the management of retinoblastoma","volume":"148","author":"Lin","year":"2009","journal-title":"Am. J. Ophthalmol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1001\/jamaophthalmol.2015.3108","article-title":"Treatment of Retinoblastoma in 2015: Agreement and Disagreement","volume":"133","author":"Abramson","year":"2015","journal-title":"JAMA Ophthalmol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ohc.2004.11.003","article-title":"Intraocular retinoblastoma: The case for a new group classification","volume":"18","year":"2005","journal-title":"Ophthalmol. Clin. N. Am."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1016\/j.ophtha.2006.06.018","article-title":"The International Classification of Retinoblastoma predicts chemoreduction success","volume":"113","author":"Shields","year":"2006","journal-title":"Ophthalmology"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3928\/0191-3913-19990101-04","article-title":"Recent developments in the management of retinoblastoma","volume":"36","author":"Shields","year":"1999","journal-title":"J. Pediatr. Ophthalmol. Strabismus"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.ajo.2004.04.032","article-title":"Chemoreduction for retinoblastoma. Analysis of tumor control and risks for recurrence in 457 tumors","volume":"138","author":"Shields","year":"2004","journal-title":"Am. J. Ophthalmol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.ophtha.2008.10.014","article-title":"Chemoreduction for group E retinoblastoma: Comparison of chemoreduction alone versus chemoreduction plus low-dose external radiotherapy in 76 eyes","volume":"116","author":"Shields","year":"2009","journal-title":"Ophthalmology"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1001\/archopht.122.5.729","article-title":"Practical approach to management of retinoblastoma","volume":"122","author":"Shields","year":"2004","journal-title":"Arch. Ophthalmol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1001\/jamaophthalmol.2016.2712","article-title":"Intra-arterial Chemotherapy for Retinoblastoma","volume":"134","author":"Shields","year":"2016","journal-title":"JAMA Ophthalmol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1016\/j.ophtha.2007.12.014","article-title":"A phase I\/II study of direct intraarterial (ophthalmic artery) chemotherapy with melphalan for intraocular retinoblastoma initial results","volume":"115","author":"Abramson","year":"2008","journal-title":"Ophthalmology"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1001\/jamaophthalmol.2016.0244","article-title":"Intra-arterial Chemotherapy for Retinoblastoma: A Systematic Review","volume":"134","author":"Yousef","year":"2016","journal-title":"JAMA Ophthalmol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/j.ophtha.2015.01.017","article-title":"The classification of vitreous seeds in retinoblastoma and response to intravitreal melphalan","volume":"122","author":"Francis","year":"2015","journal-title":"Ophthalmology"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1136\/bjophthalmol-2013-303188","article-title":"Evaluating the risk of extraocular tumour spread following intravitreal injection therapy for retinoblastoma: A systematic review","volume":"97","author":"Smith","year":"2013","journal-title":"Br. J. Ophthalmol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1016\/j.ophtha.2017.04.010","article-title":"Retinoblastoma Vitreous Seed Clouds (Class 3): A Comparison of Treatment with Ophthalmic Artery Chemosurgery with or without Intravitreous and Periocular Chemotherapy","volume":"124","author":"Francis","year":"2017","journal-title":"Ophthalmology"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3928\/01913913-20160719-04","article-title":"Retinoblastoma Control With Primary Intra-arterial Chemotherapy: Outcomes Before and During the Intravitreal Chemotherapy Era","volume":"53","author":"Shields","year":"2016","journal-title":"J. Pediatr. Ophthalmol. Strabismus"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1001\/archopht.120.7.923","article-title":"Postenucleation adjuvant therapy in high-risk retinoblastoma","volume":"120","author":"Honavar","year":"2002","journal-title":"Arch. Ophthalmol."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/pbc.22491","article-title":"High-dose chemotherapy with autologous hematopoietic stem cell rescue for stage 4B retinoblastoma","volume":"55","author":"Dunkel","year":"2010","journal-title":"Pediatr. Blood Cancer"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/pbc.22504","article-title":"Intensive multimodality therapy for patients with stage 4a metastatic retinoblastoma","volume":"55","author":"Dunkel","year":"2010","journal-title":"Pediatr. Blood Cancer"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"27082","DOI":"10.1038\/srep27082","article-title":"Risk of recurrence of retinopathy of prematurity after initial intravitreal ranibizumab therapy","volume":"6","author":"Chan","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1038\/s41433-021-01922-2","article-title":"The role of anti-vascular endothelial growth factor in treatment of retinopathy of prematurity-a current review","volume":"36","author":"Chow","year":"2022","journal-title":"Eye"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1136\/bjo.2007.134700","article-title":"Prevalence and risk factors for common vision problems in children: Data from the ALSPAC study","volume":"92","author":"Williams","year":"2008","journal-title":"Br. J. Ophthalmol."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.ophtha.2006.05.072","article-title":"Incidence and types of childhood esotropia: A population-based study","volume":"114","author":"Greenberg","year":"2007","journal-title":"Ophthalmology"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1136\/bjo.83.5.514","article-title":"Risk factors for strabismus in children born before 32 weeks\u2019 gestation","volume":"83","author":"Pennefather","year":"1999","journal-title":"Br. J. Ophthalmol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1136\/bjo.83.2.143","article-title":"Ophthalmological follow up of preterm infants: A population based, prospective study of visual acuity and strabismus","volume":"83","author":"Holmstrom","year":"1999","journal-title":"Br. J. Ophthalmol."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1001\/archopht.120.6.767","article-title":"Strabismus in children of birth weight less than 1701 g","volume":"120","author":"Stephenson","year":"2002","journal-title":"Arch. Ophthalmol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0022-3476(98)70028-9","article-title":"Presenting signs of retinoblastoma","volume":"132","author":"Abramson","year":"1998","journal-title":"J. Pediatr."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1067\/mpa.2001.114662","article-title":"The role of anisometropia in the development of accommodative esotropia","volume":"5","author":"Weakley","year":"2001","journal-title":"J. AAPOS"},{"key":"ref_87","doi-asserted-by":"crossref","unstructured":"Wright, K.W.S., and Peter, H. (2003). Pediatric Ophthalmology and Strabismus, Springer. [2nd ed.].","DOI":"10.1007\/978-0-387-21753-6"},{"key":"ref_88","doi-asserted-by":"crossref","unstructured":"American Academy of Pediatrics, Section on Ophthalmology, American Association for Pediatric, Ophthalmology, Strabismus, and American Academy of Ophthalmology (2008). American Association of Certified Orthoptists. Red reflex examination in neonates, infants, and children. Pediatrics, 122, 1401\u20131404.","DOI":"10.1542\/peds.2008-2624"},{"key":"ref_89","unstructured":"Kanukollu, V.M.S. (2022). Strabismus, StatPearls."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"P143","DOI":"10.1016\/j.ophtha.2017.10.007","article-title":"Esotropia and Exotropia Preferred Practice Pattern(R)","volume":"125","author":"PWallace","year":"2018","journal-title":"Ophthalmology"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1016\/S0161-6420(83)34413-4","article-title":"Discriminant analysis of acquired esotropia surgery. Predictor variables for short- and long-term outcomes","volume":"90","author":"Bateman","year":"1983","journal-title":"Ophthalmology"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1056\/NEJMcp051888","article-title":"Clinical practice. Pediatric strabismus","volume":"356","author":"Donahue","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1136\/bjophthalmol-2013-304627","article-title":"A systematic review of the effectiveness of treatments in altering the natural history of intermittent exotropia","volume":"99","author":"Joyce","year":"2015","journal-title":"Br. J. Ophthalmol."},{"key":"ref_94","first-page":"S94","article-title":"The outcomes of horizontal strabismus surgery and influencing factors of the surgical success","volume":"88","author":"Kampanartsanyakorn","year":"2005","journal-title":"J. Med. Assoc. Thai."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jaapos.2003.08.010","article-title":"Maximum angle of horizontal strabismus consistent with true stereopsis","volume":"8","author":"Leske","year":"2004","journal-title":"J. AAPOS"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.ajo.2020.06.002","article-title":"Pseudostrabismus in the First Year of Life and the Subsequent Diagnosis of Strabismus","volume":"218","author":"Xu","year":"2020","journal-title":"Am. J. Ophthalmol."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3368\/aoj.57.1.111","article-title":"Manifest strabismus following pseudostrabismus diagnosis","volume":"57","author":"Pritchard","year":"2007","journal-title":"Am. Orthopt. J."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"70","DOI":"10.3109\/09273972.2016.1170046","article-title":"Development of Strabismus in Children Initially Diagnosed with Pseudostrabismus","volume":"24","author":"Tugcu","year":"2016","journal-title":"Strabismus"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"940","DOI":"10.4103\/ijo.IJO_1335_17","article-title":"Community outreach: An indicator for assessment of prevalence of amblyopia","volume":"66","author":"Magdalene","year":"2018","journal-title":"Indian J. Ophthalmol."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1016\/j.ophtha.2013.03.001","article-title":"Prevalence of amblyopia or strabismus in asian and non-Hispanic white preschool children: Multi-ethnic pediatric eye disease study","volume":"120","author":"Cotter","year":"2013","journal-title":"Ophthalmology"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1136\/bjophthalmol-2019-314759","article-title":"Global prevalence of amblyopia and disease burden projections through 2040: A systematic review and meta-analysis","volume":"104","author":"Fu","year":"2020","journal-title":"Br. J. Ophthalmol."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"583","DOI":"10.3389\/fpsyg.2014.00583","article-title":"Global processing in amblyopia: A review","volume":"5","author":"Hamm","year":"2014","journal-title":"Front. Psychol."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1001\/archopht.120.3.268","article-title":"A randomized trial of atropine vs. patching for treatment of moderate amblyopia in children","volume":"120","year":"2002","journal-title":"Arch. Ophthalmol."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.ophtha.2006.01.068","article-title":"Treatment of anisometropic amblyopia in children with refractive correction","volume":"113","author":"Cotter","year":"2006","journal-title":"Ophthalmology"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1001\/archopht.121.5.603","article-title":"A randomized trial of patching regimens for treatment of moderate amblyopia in children","volume":"121","author":"Repka","year":"2003","journal-title":"Arch. Ophthalmol."},{"key":"ref_106","doi-asserted-by":"crossref","unstructured":"Li, Y., Sun, H., Zhu, X., Su, Y., Yu, T., Wu, X., Zhou, X., and Jing, L. (2020). Efficacy of interventions for amblyopia: A systematic review and network meta-analysis. BMC Ophthalmol., 20.","DOI":"10.1186\/s12886-020-01442-9"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"e000657","DOI":"10.1136\/bmjophth-2020-000657","article-title":"Efficacy of vision-based treatments for children and teens with amblyopia: A systematic review and meta-analysis of randomised controlled trials","volume":"6","author":"Brin","year":"2021","journal-title":"BMJ Open Ophthalmol."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1007\/s40123-021-00394-7","article-title":"Recent Advances in Screening and Treatment for Amblyopia","volume":"10","author":"Birch","year":"2021","journal-title":"Ophthalmol. Ther."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1038\/eye.2016.156","article-title":"Global prevalence of childhood cataract: A systematic review","volume":"30","author":"Sheeladevi","year":"2016","journal-title":"Eye"},{"key":"ref_110","first-page":"1444","article-title":"Measuring and interpreting the incidence of congenital ocular anomalies: Lessons from a national study of congenital cataract in the UK","volume":"42","author":"Rahi","year":"2001","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1034\/j.1600-0420.1999.770520.x","article-title":"The occurrence of congenital cataract in western Sweden","volume":"77","author":"Abrahamsson","year":"1999","journal-title":"Acta Ophthalmol Scand."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1076\/opep.10.2.67.13894","article-title":"Birth prevalence of visually significant infantile cataract in a defined U.S. population","volume":"10","author":"Holmes","year":"2003","journal-title":"Ophthalmic. Epidemiol."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.4103\/ijo.IJO_1023_17","article-title":"Pediatric cataract","volume":"65","author":"Khokhar","year":"2017","journal-title":"Indian. J Ophthalmol."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/S0161-6420(81)80034-6","article-title":"Bruckner test","volume":"88","author":"Tongue","year":"1981","journal-title":"Ophthalmology"},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/S0031-3955(16)34502-3","article-title":"Cataracts in children","volume":"30","author":"Calhoun","year":"1983","journal-title":"Pediatr. Clin. North. Am."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.21037\/atm-20-3033","article-title":"Recent developments in the management of congenital cataract","volume":"8","author":"Daruich","year":"2020","journal-title":"Ann. Transl. Med."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S1091-8531(98)90009-X","article-title":"Visual outcomes after surgery for unilateral cataract in children more than two years old: Posterior chamber intraocular lens implantation versus contact lens correction of aphakia","volume":"2","author":"Greenwald","year":"1998","journal-title":"J. AAPOS"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1001\/jamaophthalmol.2014.531","article-title":"Comparison of contact lens and intraocular lens correction of monocular aphakia during infancy: A randomized clinical trial of HOTV optotype acuity at age 4.5 years and clinical findings at age 5 years","volume":"132","author":"Lambert","year":"2014","journal-title":"JAMA Ophthalmol."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.ophtha.2020.07.020","article-title":"Outcomes of Bilateral Cataract Surgery in Infants 7 to 24 Months of Age Using the Toddler Aphakia and Pseudophakia Treatment Study Registry","volume":"128","author":"Bothun","year":"2021","journal-title":"Ophthalmology"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1001\/jamaophthalmol.2015.2062","article-title":"Long-term results of pediatric cataract surgery and primary intraocular lens implantation from 7 to 22 months of life","volume":"133","author":"Struck","year":"2015","journal-title":"JAMA Ophthalmol."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1038\/s41433-020-1115-6","article-title":"Cataract management in children: A review of the literature and current practice across five large UK centres","volume":"34","author":"Self","year":"2020","journal-title":"Eye"},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0031-3955(02)00110-4","article-title":"Childhood glaucoma","volume":"50","author":"Kipp","year":"2003","journal-title":"Pediatr. Clin. North Am."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0039-6257(83)90174-1","article-title":"Primary infantile glaucoma (congenital glaucoma)","volume":"28","author":"deLuise","year":"1983","journal-title":"Surv Ophthalmol"},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1046\/j.1442-9071.2004.00750.x","article-title":"Primary infantile glaucoma in an Australian population","volume":"32","author":"MacKinnon","year":"2004","journal-title":"Clin. Exp. Ophthalmol."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.ajo.2012.12.006","article-title":"Primary and secondary congenital glaucoma: Baseline features from a registry at King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia","volume":"155","author":"Alanazi","year":"2013","journal-title":"Am. J. Ophthalmol."},{"key":"ref_126","first-page":"76","article-title":"Epidemiology and genetics of primary congenital glaucoma in Slovakia. Description of a form of primary congenital glaucoma in gypsies with autosomal-recessive inheritance and complete penetrance","volume":"16","author":"Gencik","year":"1989","journal-title":"Dev. Ophthalmol."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.optm.2006.10.016","article-title":"A case of primary congenital glaucoma: A diagnostic dilemma","volume":"78","author":"Girgis","year":"2007","journal-title":"Optometry"},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"92","DOI":"10.5005\/jp-journals-10008-1192","article-title":"Review on the Management of Primary Congenital Glaucoma","volume":"9","author":"Choy","year":"2015","journal-title":"J. Curr. Glaucoma. Pract."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/ICU.0000000000000349","article-title":"Pediatric glaucoma: Review of recent literature","volume":"28","author":"Giangiacomo","year":"2017","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"e000933","DOI":"10.1136\/bmjophth-2021-000933","article-title":"A systematic review of clinical practice guidelines for childhood glaucoma","volume":"7","author":"Lingham","year":"2022","journal-title":"BMJ Open Ophthalmol."},{"key":"ref_131","doi-asserted-by":"crossref","unstructured":"Shah, M., Bouhenni, R., and Benmerzouga, I. (2022). Geographical Variability in CYP1B1 Mutations in Primary Congenital Glaucoma. J. Clin. Med., 11.","DOI":"10.3390\/jcm11072048"},{"key":"ref_132","first-page":"CD008213","article-title":"Surgical interventions for primary congenital glaucoma","volume":"1","author":"Ghate","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3928\/0191-3913-19840701-06","article-title":"Goniotomy vs trabeculotomy","volume":"21","author":"Hoskins","year":"1984","journal-title":"J. Pediatr. Ophthalmol. Strabismus"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1016\/j.ophtha.2011.03.010","article-title":"Comparison of latanoprost and timolol in pediatric glaucoma: A phase 3, 12-week, randomized, double-masked multicenter study","volume":"118","author":"Simons","year":"2011","journal-title":"Ophthalmology"},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3928\/01913913-20090101-05","article-title":"The safety and efficacy of glaucoma medication in the pediatric population","volume":"46","author":"Coppens","year":"2009","journal-title":"J. Pediatr. Ophthalmol. Strabismus"},{"key":"ref_136","first-page":"736","article-title":"Axenfeld-Rieger syndrome: A theory of mechanism and distinctions from the iridocorneal endothelial syndrome","volume":"81","author":"Shields","year":"1983","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1097\/ICO.0b013e31820156a9","article-title":"Peters anomaly: Review of the literature","volume":"30","author":"Bhandari","year":"2011","journal-title":"Cornea"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1159\/000309345","article-title":"Corticosteroid glaucoma","volume":"188","author":"Francois","year":"1984","journal-title":"Ophthalmologica"},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/S0161-6420(95)30906-2","article-title":"A prospective study of ocular hypertension and glaucoma after pediatric cataract surgery","volume":"102","author":"Egbert","year":"1995","journal-title":"Ophthalmology"},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3928\/0191-3913-19830901-06","article-title":"Congenital aniridia: A histopathologic study of the anterior segment in children","volume":"20","author":"Margo","year":"1983","journal-title":"J. Pediatr. Ophthalmol. Strabismus"},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.jaapos.2009.04.007","article-title":"Port-wine vascular malformations and glaucoma risk in Sturge-Weber syndrome","volume":"13","author":"Sharan","year":"2009","journal-title":"J. AAPOS"},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1001\/jamaophthalmol.2017.3319","article-title":"Epidemiology of Conjunctivitis in US Emergency Departments","volume":"135","author":"Ramirez","year":"2017","journal-title":"JAMA Ophthalmol."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1136\/bmj.327.7418.789","article-title":"Diagnostic impact of signs and symptoms in acute infectious conjunctivitis: Systematic literature search","volume":"327","author":"Rietveld","year":"2003","journal-title":"BMJ"},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1097\/00003226-199507000-00007","article-title":"Adenoviral ocular isolates demonstrate serotype-dependent differences in in vitro infectivity titers and clinical course","volume":"14","author":"Roba","year":"1995","journal-title":"Cornea"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1001\/jama.2013.280318","article-title":"Conjunctivitis: A systematic review of diagnosis and treatment","volume":"310","author":"Azari","year":"2013","journal-title":"JAMA"},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1542\/pir.31.5.196","article-title":"Conjunctivitis","volume":"31","author":"Richards","year":"2010","journal-title":"Pediatr. Rev."},{"key":"ref_147","unstructured":"Ryder, E.C., and Benson, S. (2022). Conjunctivitis, StatPearls."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0733-8635(18)30318-8","article-title":"Ocular effects of topical and systemic steroids","volume":"10","author":"Renfro","year":"1992","journal-title":"Dermatol. Clin."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1136\/bjo.2010.188623","article-title":"A randomised placebo-controlled trial of topical steroid in presumed viral conjunctivitis","volume":"95","author":"Wilkins","year":"2011","journal-title":"Br. J. Ophthalmol."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0002-9394(14)70640-3","article-title":"Possible consequences of shaking hands with your patients with epidemic keratoconjunctivitis","volume":"121","author":"Azar","year":"1996","journal-title":"Am. J. Ophthalmol."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1600-0420.2007.01006.x","article-title":"Acute bacterial conjunctivitis","volume":"86","author":"Hovding","year":"2008","journal-title":"Acta Ophthalmol."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr7004a1","article-title":"Sexually Transmitted Infections Treatment Guidelines, 2021","volume":"70","author":"Workowski","year":"2021","journal-title":"MMWR Recomm. Rep."},{"key":"ref_153","doi-asserted-by":"crossref","unstructured":"US Preventive Services Task Force, Curry, S.J., Krist, A.H., Owens, D.K., Barry, M.J., Caughey, A.B., Davidson, K.W., Doubeni, C.A., Epling, J.W., and Kemper, A.R. (2019). Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA, 321, 394\u2013398.","DOI":"10.1001\/jama.2018.21367"},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1097\/INF.0000000000002114","article-title":"Management of Herpes Simplex Virus Keratitis in the Pediatric Population","volume":"37","author":"Vadoothker","year":"2018","journal-title":"Pediatr. Infect. Dis. J."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/eye.1998.166","article-title":"The natural history of epiphora in childhood","volume":"12","author":"Maini","year":"1998","journal-title":"Eye"},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/IIO.0000000000000030","article-title":"Update on congenital nasolacrimal duct obstruction","volume":"54","author":"Olitsky","year":"2014","journal-title":"Int. Ophthalmol. Clin."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"2430","DOI":"10.1016\/j.ophtha.2010.03.030","article-title":"Developmental anatomy of the nasolacrimal duct: Implications for congenital obstruction","volume":"117","author":"Moscato","year":"2010","journal-title":"Ophthalmology"},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.pcl.2014.03.002","article-title":"The lacrimal system","volume":"61","author":"Orge","year":"2014","journal-title":"Pediatr. Clin. N. Am."},{"key":"ref_159","unstructured":"Pezzoli, M.P., and Bhupendra, C. (2022). Dacryostenosis, StatPearls."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1001\/jamaophthalmol.2018.3841","article-title":"Spontaneous Resolution and Timing of Intervention in Congenital Nasolacrimal Duct Obstruction","volume":"136","author":"Sathiamoorthi","year":"2018","journal-title":"JAMA Ophthalmol."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"246","DOI":"10.3928\/0191-3913-19780701-14","article-title":"The natural course of congenital obstruction of the nasolacrimal duct","volume":"15","author":"Petersen","year":"1978","journal-title":"J. Pediatr. Ophthalmol. Strabismus"},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/eye.1991.103","article-title":"Epiphora during the first year of life","volume":"5","author":"MacEwen","year":"1991","journal-title":"Eye"},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1001\/archopht.1982.01030030599010","article-title":"Congenital nasolacrimal system obstruction","volume":"100","author":"Kushner","year":"1982","journal-title":"Arch. Ophthalmol."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/ICU.0b013e3283642e94","article-title":"Pediatric nasolacrimal duct obstruction","volume":"24","author":"Schnall","year":"2013","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1001\/archophthalmol.2012.2853","article-title":"A randomized trial comparing the cost-effectiveness of 2 approaches for treating unilateral nasolacrimal duct obstruction","volume":"130","year":"2012","journal-title":"Arch. Ophthalmol."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1034\/j.1600-0420.2000.078006694.x","article-title":"Bacteriology and antibiotic therapy in congenital nasolacrimal duct obstruction","volume":"78","author":"Kuchar","year":"2000","journal-title":"Acta Ophthalmol. Scand."},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/BF00160761","article-title":"The postsaccal, idiopathic dacryostenosis--experimental and clinical aspects","volume":"63","author":"Steinkogler","year":"1986","journal-title":"Doc. Ophthalmol."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.jaapos.2008.04.006","article-title":"The timing of antibiotic administration in the management of infant dacryocystitis","volume":"12","author":"Baskin","year":"2008","journal-title":"J. AAPOS"},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/j.ophtha.2010.10.026","article-title":"Incidence and demographics of childhood ptosis","volume":"118","author":"Griepentrog","year":"2011","journal-title":"Ophthalmology"},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"453","DOI":"10.2147\/OPTH.S111118","article-title":"Clinical presentation and management of congenital ptosis","volume":"11","author":"Marenco","year":"2017","journal-title":"Clin. Ophthalmol."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1038\/eye.1999.136","article-title":"Corneal topography in patients with congenital ptosis","volume":"13","author":"Ugurbas","year":"1999","journal-title":"Eye"},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/eye.1988.115","article-title":"Amblyopia and strabismus in congenital ptosis","volume":"2","author":"Harrad","year":"1988","journal-title":"Eye"},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1046\/j.1442-9071.2003.00621.x","article-title":"Blepharophimosis: A recommendation for early surgery in patients with severe ptosis","volume":"31","author":"Beckingsale","year":"2003","journal-title":"Clin. Exp. Ophthalmol."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.ophtha.2006.11.017","article-title":"Treatment of unilateral congenital ptosis","volume":"114","author":"Bernardini","year":"2007","journal-title":"Ophthalmology"},{"key":"ref_175","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/j.1525-1470.2008.00626.x","article-title":"Infantile hemangiomas: How common are they? A systematic review of the medical literature","volume":"25","author":"Kilcline","year":"2008","journal-title":"Pediatr. Dermatol."},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1001\/archderm.136.7.905","article-title":"Benign cutaneous vascular tumors of infancy: When to worry, what to do","volume":"136","author":"Metry","year":"2000","journal-title":"Arch. Dermatol."},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1542\/peds.2007-2767","article-title":"Growth characteristics of infantile hemangiomas: Implications for management","volume":"122","author":"Chang","year":"2008","journal-title":"Pediatrics"},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1056\/NEJM199907153410307","article-title":"Hemangiomas in children","volume":"341","author":"Drolet","year":"1999","journal-title":"N. Engl. J. Med."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"3946","DOI":"10.1542\/peds.2018-3475","article-title":"Clinical Practice Guideline for the Management of Infantile Hemangiomas","volume":"143","author":"Krowchuk","year":"2019","journal-title":"Pediatrics"},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ajo.2012.06.021","article-title":"Treatment of infantile capillary hemangioma of the eyelid with systemic propranolol","volume":"155","author":"Vassallo","year":"2013","journal-title":"Am. J. Ophthalmol."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.jaapos.2007.04.022","article-title":"Treatment of capillary hemangiomas causing refractive and occlusional amblyopia","volume":"11","author":"Schwartz","year":"2007","journal-title":"J. AAPOS"},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1097\/IOP.0000000000001466","article-title":"Surgical Intervention of Periocular Infantile Hemangiomas in the Era of beta-Blockers","volume":"36","author":"Men","year":"2020","journal-title":"Ophthalmic. Plast. Reconstr. Surg."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.jaad.2007.10.492","article-title":"Laser treatment of pediatric vascular lesions: Port wine stains and hemangiomas","volume":"58","author":"Stier","year":"2008","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.survophthal.2004.02.001","article-title":"Orbital cysts of childhood\u2013classification, clinical features, and management","volume":"49","author":"Shields","year":"2004","journal-title":"Surv. Ophthalmol."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"337","DOI":"10.3928\/01913913-20061101-02","article-title":"Current trends in the surgical management of orbital dermoid cysts among pediatric ophthalmologists","volume":"43","author":"Yen","year":"2006","journal-title":"J. Pediatr. Ophthalmol. Strabismus"},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s10792-011-9419-y","article-title":"Orbital dermoid cyst of childhood: Clinical pathologic findings, classification and management","volume":"31","author":"Cavazza","year":"2011","journal-title":"Int. Ophthalmol."},{"key":"ref_187","first-page":"CD005020","article-title":"Vision screening for amblyopia in childhood","volume":"3","author":"Powell","year":"2009","journal-title":"Cochrane Database Syst. 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