{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T02:40:44Z","timestamp":1794019244463,"version":"4.8.0"},"reference-count":87,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T00:00:00Z","timestamp":1739145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CIMB"],"abstract":"<jats:p>In vitro embryo production has accelerated in the cattle industry in recent years. Because women are similar to cows, this represents an opportunity to improve women\u2019s reproductive protocols. This review focuses on crosstalk communication during folliculogenesis for an in-depth understanding of the events involved in developing the oocyte competence necessary to generate an embryo after fertilization. This knowledge can be used to improve oocytes in in vitro maturation cultures, which would allow us to obtain oocytes of high quality and competence, resulting in successful pregnancies in both women and cows. The first part of this review covers the concepts of cellular crosstalk before puberty in the primordial, primary, and secondary follicles. The next part involves cellular crosstalk after puberty, when gonadotropin hormones act on the ovary, promoting oocyte maturation. The final part comprises a perspective on using cow models to study human ovary physiology.<\/jats:p>","DOI":"10.3390\/cimb47020113","type":"journal-article","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T04:44:03Z","timestamp":1739162643000},"page":"113","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Folliculogenesis: A Cellular Crosstalk Mechanism"],"prefix":"10.3390","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8325-4086","authenticated-orcid":false,"given":"Bianca Viviana","family":"Orozco-Galindo","sequence":"first","affiliation":[{"name":"Facultad de Zootecnia y Ecolog\u00eda, Universidad Aut\u00f3noma de Chihuahua (UACH), Perif. Fco. R. Almada Km. 1, 31453 Chihuahua, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7284-7855","authenticated-orcid":false,"given":"Blanca","family":"S\u00e1nchez-Ram\u00edrez","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Qu\u00edmicas, Universidad Aut\u00f3noma de Chihuahua (UACH), Campus Universitario #2, 31125 Chihuahua, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2720-7242","authenticated-orcid":false,"given":"Cynthia Lizeth","family":"Gonz\u00e1lez-Trevizo","sequence":"additional","affiliation":[{"name":"School of Engineering and Sciences, Tecnologico de Monterrey, Av. H. Colegio Militar 4700, Nombre de Dios, 31300 Chihuahua, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Castro-Valenzuela","sequence":"additional","affiliation":[{"name":"Facultad de Zootecnia y Ecolog\u00eda, Universidad Aut\u00f3noma de Chihuahua (UACH), Perif. Fco. R. Almada Km. 1, 31453 Chihuahua, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8808-8403","authenticated-orcid":false,"given":"Luis","family":"Varela-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Qu\u00edmicas, Universidad Aut\u00f3noma de Chihuahua (UACH), Campus Universitario #2, 31125 Chihuahua, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6945-4604","authenticated-orcid":false,"given":"M. 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