{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:01:18Z","timestamp":1760148078517,"version":"build-2065373602"},"reference-count":39,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T00:00:00Z","timestamp":1679875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Italian Ministry of Health\u2014Current Research 2022"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>The purpose of this study was to investigate the effects of a \u201chuman immersion model\u201d (HIM) in improving psychological well-being in caregivers of patients with acquired brain injury (ABI) during the Omicron wave in Italy. Fifteen subjects affected by ABI, who attended our intensive neurorehabilitation unit from January to March 2022 and their caregivers were submitted to the HIM. This novel approach consisted of \u201creal\u201d long-lasting meetings between the patients and their careers in a hospital setting (1\u201372 h meeting per week for 8 weeks). Each ABI caregiver was assessed through the administration of a short psychometric battery before starting the first immersion session with their family member and at the end of the HIM. We found significant changes in the caregivers\u2019 scores analyzed for anxiety, as per SAS (p &lt; 0.0007, d = 1.02), burden and stress (ZBI-22; p &lt; 0.001, d = 0.65), and emotive intelligence (TEIQue-SF; p &lt; 0.0007, d = 0.82). Our data suggest that the HIM may be useful to promote ABI caregivers\u2019 psycho-emotional well-being in the context of critical periods such as the COVID-19 pandemic.<\/jats:p>","DOI":"10.3390\/clinpract13020044","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T06:46:19Z","timestamp":1679899579000},"page":"487-496","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Psycho-Emotional Well-Being in Caregivers of People with Acquired Brain Injury: An Exploratory Study on the Human Immersion Model during the Omicron Wave"],"prefix":"10.3390","volume":"13","author":[{"given":"Rosaria","family":"De Luca","sequence":"first","affiliation":[{"name":"IRCCS Centro Neurolesi \u201cBonino-Pulejo\u201d, 98123 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrizia","family":"Pollicino","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi \u201cBonino-Pulejo\u201d, 98123 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmela","family":"Rifici","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi \u201cBonino-Pulejo\u201d, 98123 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natale","family":"Mondo","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi \u201cBonino-Pulejo\u201d, 98123 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Iorio","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi \u201cBonino-Pulejo\u201d, 98123 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Cassaniti","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi \u201cBonino-Pulejo\u201d, 98123 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donatella","family":"Ferrara","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi \u201cBonino-Pulejo\u201d, 98123 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Caminiti","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi \u201cBonino-Pulejo\u201d, 98123 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9017-1991","authenticated-orcid":false,"given":"Fausto","family":"Fam\u00e0","sequence":"additional","affiliation":[{"name":"Department of Human Pathology in Adulthood and Childhood \u201cG. Barresi\u201d, University Hospital \u201cG. Martino\u201d, 98125 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3284-9741","authenticated-orcid":false,"given":"Mirjam","family":"Bonanno","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi \u201cBonino-Pulejo\u201d, 98123 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8566-3166","authenticated-orcid":false,"given":"Rocco Salvatore","family":"Calabr\u00f2","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi \u201cBonino-Pulejo\u201d, 98123 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1002\/mco2.110","article-title":"SARS-CoV-2 Omicron variant: Characteristics and prevention","volume":"2","author":"He","year":"2021","journal-title":"MedComm"},{"key":"ref_2","first-page":"8012","article-title":"Omicron SARS-CoV-2 new variant: Global prevalence and biological and clinical characteristics","volume":"25","author":"Meo","year":"2021","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"648286","DOI":"10.3389\/fpsyg.2021.648286","article-title":"The Impact of Psycho-Social Interventions on the Wellbeing of Individuals with Acquired Brain Injury During the COVID-19 Pandemic","volume":"12","author":"Wilkie","year":"2021","journal-title":"Front. Psychol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"World Health Organization (2022, January 27). Contact Tracing in the Context of COVID-19. Interim Guidance: 1 February 2021. Available online: https:\/\/www.who.int\/publications\/i\/item\/contact-tracing-in-the-context-of-covid-19.","DOI":"10.15557\/PiMR.2020.0005"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"(2022, January 27). Considerations for Quarantine of Contacts of COVID-19 Cases. Interim Guidance: 25 June 2021. Available online: https:\/\/www.who.int\/publications\/i\/item\/WHO-2019-nCoV-IHR-Quarantine-2021.1.","DOI":"10.17081\/psico.25.47.4549"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1080\/02699050802158243","article-title":"Perspectives of survivors of traumatic brain injury and their caregivers on long-term social integration","volume":"22","author":"Lefebvre","year":"2008","journal-title":"Brain Inj."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1002\/jclp.23082","article-title":"How the COVID-19 pandemic has changed our lives: A study of psychological correlates across 59 countries","volume":"77","author":"Alzueta","year":"2021","journal-title":"J. Clin. Psychol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.jcbs.2020.07.010","article-title":"COVID-19: Psychological flexibility, coping, mental health, and wellbeing in the UK during the pandemic","volume":"17","author":"Dawson","year":"2020","journal-title":"J. Contextual. Behav. Sci."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Groarke, J.M., Berry, E., Graham-Wisener, L., McKenna-Plumley, P.E., McGlinchey, E., and Armour, C. (2020). Loneliness in the UK during the COVID-19 pandemic: Cross-sectional results from the COVID-19 Psychological Wellbeing Study. PLoS ONE, 15.","DOI":"10.31234\/osf.io\/j2pce"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3109\/02699052.2015.1113569","article-title":"The experience of discharge for patients with an acquired brain injury from the inpatient to the community setting: A qualitative review","volume":"30","author":"Piccenna","year":"2016","journal-title":"Brain Inj."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/S0140-6736(21)02046-8","article-title":"Considerations in boosting COVID-19 vaccine immune responses","volume":"398","author":"Krause","year":"2021","journal-title":"Lancet"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"612747","DOI":"10.3389\/fimmu.2021.612747","article-title":"Optimize Prime\/Boost Vaccine Strategies: Trained Immunity as a New Player in the Game","volume":"12","author":"Palgen","year":"2021","journal-title":"Front. Immunol."},{"key":"ref_13","first-page":"1357633X21990195","article-title":"\u2018Online therapy\u2019 to reduce caregiver\u2019s distress and to stimulate post-severe acquired brain injury motor and cognitive recovery: A Sicilian hospital experience in the COVID era","volume":"2021","author":"Rifici","year":"2021","journal-title":"J. Telemed. Telecare"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"De Luca, R., Rifici, C., Pollicino, P., Parisi, S., Bonanno, M., Torregrossa, W., Ferrara, D., Caminiti, A., Piccione, M., and Calabr\u00f2, R.S. (2022). Is the \u201cFamily Glass Cabin\u201d Useful to Safely Allow Inpatient-Caregiver Interaction in the COVID-19 Era? A Pilot Study on Severe Acquired Brain Injury. J. Clin. Med., 11.","DOI":"10.3390\/jcm11061623"},{"key":"ref_15","unstructured":"Tyerman, A. (2020, December 29). The Impact of Lockdown on Brain Injury Survivors and Their Families. Available online: https:\/\/www.headway.org.uk\/media\/8564\/the-impact-of-lockdown-on-brain-injury-survivors-and-their-families.pdf."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0033-3182(71)71479-0","article-title":"A rating instrument for anxiety disorders","volume":"12","author":"Zung","year":"1971","journal-title":"Psychosomatics"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1093\/geront\/20.6.649","article-title":"Relatives of the impaired elderly: Correlates of feelings of burden","volume":"20","author":"Zarit","year":"1980","journal-title":"Gerontologist"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1080\/00223891.2010.497426","article-title":"A psychometric analysis of the Trait Emotional Intelligence Questionnaire\u2013Short Form (TEIQue\u2013SF) using item response theory","volume":"92","author":"Cooper","year":"2010","journal-title":"J. Pers. Assess"},{"key":"ref_19","unstructured":"Stough, C., Saklofske, D., and Parker, J.D. Advances in the Assessment of Emotional Intelligence, Springer."},{"key":"ref_20","unstructured":"R Core Team (2022). R: A Language and Environment for Statistical Computing, R Foundation for Statistical Computing. Available online: https:\/\/www.R-project.org\/."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1080\/02699052.2016.1225987","article-title":"The experience of patients with ABI and their families during the hospital stay: A systematic review of qualitative literature","volume":"31","author":"Oyesanya","year":"2017","journal-title":"Brain Inj."},{"key":"ref_22","first-page":"438","article-title":"Caregiver burden: A concept analysis","volume":"7","author":"Liu","year":"2020","journal-title":"Int. J. Nurs. Sci."},{"key":"ref_23","first-page":"e1590","article-title":"Caregiver\u2019s Burden of the Patients with Traumatic Brain Injury","volume":"9","author":"Qadeer","year":"2017","journal-title":"Cureus"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"790","DOI":"10.3389\/fpsyt.2020.00790","article-title":"COVID-19 Pandemic and Lockdown Measures Impact on Mental Health Among the General Population in Italy","volume":"11","author":"Rossi","year":"2020","journal-title":"Front. Psychiatry"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1177\/0269215506071279","article-title":"Stress and depression in family carers following traumatic brain injury: The influence of beliefs about difficult behaviours","volume":"21","author":"Riley","year":"2007","journal-title":"Clin. Rehabil."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1080\/02699050600743725","article-title":"Predictors of family system functioning after brain injury","volume":"20","author":"Gan","year":"2006","journal-title":"Brain Inj."},{"key":"ref_27","first-page":"8866534","article-title":"Families\u2019 Experiences Living with Acquired Brain Injury: \u201cThinking Family\u201d-A Nursing Pathway for Family-Centered Care","volume":"2020","author":"Karpa","year":"2020","journal-title":"Nurs. Res. Pract."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1002\/hpm.3008","article-title":"The coronavirus (COVID-19) pandemic\u2019s impact on mental health","volume":"35","author":"Javed","year":"2020","journal-title":"Int. J. Health Plann. Manag."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"114015","DOI":"10.1016\/j.psychres.2021.114015","article-title":"Self-isolation, psychotic symptoms and cognitive problems during the COVID-19 worldwide outbreak","volume":"302","author":"Berntsen","year":"2021","journal-title":"Psychiatry Res."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"210287","DOI":"10.1098\/rsos.210287","article-title":"Social touch deprivation during COVID-19: Effects on psychological wellbeing and craving interpersonal touch","volume":"8","author":"Kirsch","year":"2021","journal-title":"R. Soc. Open Sci."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Keyan, D., Dawson, K., Azevado, S., Yadav, S., Tran, J., and Bryant, R.A. (2021). Brief videoconferencing psychological intervention for reducing COVID-19 related distress: Study protocol for a randomized controlled trial. BMC Public Health, 21.","DOI":"10.1186\/s12889-021-10529-x"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2333721421999279","DOI":"10.1177\/2333721421999279","article-title":"Exploring Changes in Caregiver Burden and Caregiving Intensity due to COVID-19","volume":"7","author":"Cohen","year":"2021","journal-title":"Gerontol. Geriatr. Med."},{"key":"ref_33","first-page":"1529","article-title":"Self-soothing behaviors with particular reference to oxytocin release induced by non-noxious sensory stimulation","volume":"5","author":"Handlin","year":"2015","journal-title":"Front. Psychol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"783694","DOI":"10.3389\/fpsyg.2022.783694","article-title":"Therapeutic Alliance as Active Inference: The Role of Therapeutic Touch and Synchrony","volume":"13","author":"McParlin","year":"2022","journal-title":"Front. Psychol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.tics.2012.01.005","article-title":"Ventromedial prefrontal-subcortical systems and the generation of affective meaning","volume":"16","author":"Roy","year":"2012","journal-title":"Trends Cogn. Sci."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1098\/rstb.2006.1941","article-title":"Social buffering: Relief from stress and anxiety","volume":"361","author":"Kikusui","year":"2006","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.2522\/ptj.20090349","article-title":"The role of caregiver involvement in upper-limb treatment in individuals with subacute stroke","volume":"90","author":"Harris","year":"2010","journal-title":"Phys Ther."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1016\/j.apmr.2017.02.021","article-title":"Caregivers: Do they make a difference to patient recovery in subacute stroke?","volume":"98","author":"Ong","year":"2017","journal-title":"Arch. Phys. Med. Rehab."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1007\/s11606-018-4417-7","article-title":"Interventions that support or involve caregivers or families of patients with traumatic injury: A systematic review","volume":"33","author":"Shapiro","year":"2018","journal-title":"J. Gen. Intern."}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2039-7283\/13\/2\/44\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:03:58Z","timestamp":1760123038000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/13\/2\/44"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,27]]},"references-count":39,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["clinpract13020044"],"URL":"https:\/\/doi.org\/10.3390\/clinpract13020044","relation":{},"ISSN":["2039-7283"],"issn-type":[{"type":"electronic","value":"2039-7283"}],"subject":[],"published":{"date-parts":[[2023,3,27]]}}}