{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:28:55Z","timestamp":1760149735481,"version":"build-2065373602"},"reference-count":40,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T00:00:00Z","timestamp":1693958400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>The infrapatellar branch of the saphenous nerve (SN) is a widely described anatomic and functional structure; however, its relevance in daily clinical practice is underestimated. All surgical procedures performed on the anteromedial aspect of the knee are associated with a risk of iatrogenic injury to this nerve, including knee arthroscopy, knee arthroplasty, tibial nailing, etc. We present the case of a saphenous nerve neuroma after treatment with radiofrequency thermal ablation due to a knee pain problem. After conducting an anaesthetic suppression test, we decided to perform a denervation of the medial saphenous nerve in Hunter\u2019s canal. We performed surgery on the anteromedial aspect of the knee. The distal end of the medial SN was coagulated with a bipolar scalpel. The proximal end of the nerve was released proximally, and a termino-lateral suture was made at the free end of the nerve after creating an epineural window to inhibit its growth. A double crush was produced proximally to the suture site to create a grade II-III axonal injury. Autologous plasma rich in growth factors (PRGF) was used to reduce potential post-surgical adhesions and to stimulate regeneration of the surgical lesions. One year after surgery, the patient was living a completely normal life.<\/jats:p>","DOI":"10.3390\/clinpract13050097","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T10:34:57Z","timestamp":1693996497000},"page":"1090-1099","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Surgical Treatment of Saphenous Nerve Injury Assisted by Plasma Rich in Growth Factors (PRGF): Lessons from a Case Report"],"prefix":"10.3390","volume":"13","author":[{"given":"Homid","family":"Fahandezh-Saddi D\u00edaz","sequence":"first","affiliation":[{"name":"Hand and Upper Extremity Surgery Unit, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n, 28922 Alcorc\u00f3n, Spain"},{"name":"Unit for Ultrasound-Guided Surgery, Hospital Beata Mar\u00eda Ana, 28007 Madrid, Spain"},{"name":"Department of Traumatology and Orthopedic Surgery, Avanfi Institute, 28015 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0369-2848","authenticated-orcid":false,"given":"Antonio","family":"R\u00edos Luna","sequence":"additional","affiliation":[{"name":"Department of Traumatology and Orthopedic Surgery, Cl\u00ednica Orthoindal, 04004 Almer\u00eda, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Villanueva Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Unit for Ultrasound-Guided Surgery, Hospital Beata Mar\u00eda Ana, 28007 Madrid, Spain"},{"name":"Department of Traumatology and Orthopedic Surgery, Avanfi Institute, 28015 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Elena","family":"Cantero Yubero","sequence":"additional","affiliation":[{"name":"GP Doctor, \u00c1rea Oeste, CL Arroyomolinos, 28939 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4767-7206","authenticated-orcid":false,"given":"Roberto","family":"Prado","sequence":"additional","affiliation":[{"name":"Regenerative Medicine Laboratory, BTI\u2014Biotechnology Institute I MAS D, 01007 Vitoria, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabino","family":"Padilla","sequence":"additional","affiliation":[{"name":"Regenerative Medicine Laboratory, BTI\u2014Biotechnology Institute I MAS D, 01007 Vitoria, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8386-5303","authenticated-orcid":false,"given":"Eduardo","family":"Anitua","sequence":"additional","affiliation":[{"name":"Regenerative Medicine Laboratory, BTI\u2014Biotechnology Institute I MAS D, 01007 Vitoria, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.athoracsur.2007.11.032","article-title":"Surgical anatomy of the saphenous nerve","volume":"85","author":"Dayan","year":"2008","journal-title":"Ann. 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