{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T04:08:15Z","timestamp":1773806895130,"version":"3.50.1"},"reference-count":75,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T00:00:00Z","timestamp":1698278400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department of Urology, Tulane University School of Medicine"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>The COVID-19 pandemic due to the SARS-CoV-2 coronavirus showed acute and prolonged effects on human health. In addition, over the past four years, there has been a tremendous surge in COVID-19-related scientific publications, as shown by bibliometric and scientometric studies. However, such analysis of the scientific literature is lacking in the area of male reproduction. The current scientometric study analyzes publication characteristics of articles related to male reproduction and COVID-19 infection. We used the Scopus database to analyze scientometric data (the number of publications, journals, countries, type of documents, and subject area) related to COVID-19 and male reproductive research. Our literature search identified 345 articles related to COVID-19 and male reproductive research. Most of the articles were published in the USA (n = 72), Italy (n = 55), and China (n = 51). Such research was mainly focused around medicine (57.1%), followed by biochemistry, genetics, and molecular biology (25.7%). Also, in the area of male reproduction, only 37.1% (n = 128) of the articles contributed towards original research, whereas 52.8% (n = 182) were review articles and editorials focusing more on sexual dysfunction than infertility. Such a small number of studies published on COVID-19-related effects on male reproduction warrants a significant increase in research, which is required to decipher the mechanism(s) underlying SARS-CoV-2 infection-associated impairment of male reproductive function.<\/jats:p>","DOI":"10.3390\/clinpract13060118","type":"journal-article","created":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T07:22:15Z","timestamp":1698304935000},"page":"1319-1330","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Scientometric Evaluation of COVID-19 and Male Reproductive Research"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9120-2278","authenticated-orcid":false,"given":"Manesh Kumar","family":"Panner Selvam","sequence":"first","affiliation":[{"name":"Department of Urology, School of Medicine, Tulane University, New Orleans, LA 70112, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anika","family":"Kapoor","sequence":"additional","affiliation":[{"name":"The Hockaday School, Dallas, TX 75229, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4499-8680","authenticated-orcid":false,"given":"Saradha","family":"Baskaran","sequence":"additional","affiliation":[{"name":"Department of Urology, School of Medicine, Tulane University, New Orleans, LA 70112, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6928-218X","authenticated-orcid":false,"given":"Ajaya Kumar","family":"Moharana","sequence":"additional","affiliation":[{"name":"Department of Urology, School of Medicine, Tulane University, New Orleans, LA 70112, USA"},{"name":"Redox Biology & Proteomics Laboratory, Department of Zoology, School of Life Sciences, Ravenshaw University, Cuttack 753003, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suresh C.","family":"Sikka","sequence":"additional","affiliation":[{"name":"Department of Urology, School of Medicine, Tulane University, New Orleans, LA 70112, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,26]]},"reference":[{"key":"ref_1","unstructured":"WHO (2023, July 30). 14.9 Million Excess Deaths Associated with the COVID-19 Pandemic in 2020 and 2021. Available online: https:\/\/www.who.int\/news\/item\/05-05-2022-14.9-million-excess-deaths-were-associated-with-the-covid-19-pandemic-in-2020-and-2021."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"5578284","DOI":"10.1155\/2022\/5578284","article-title":"COVID-19 Impact on Public Health, Environment, Human Psychology, Global Socioeconomy, and Education","volume":"2022","author":"Miyah","year":"2022","journal-title":"Sci. World J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"e046863","DOI":"10.1136\/bmjopen-2020-046863","article-title":"Economic and social impacts of COVID-19 and public health measures: Results from an anonymous online survey in Thailand, Malaysia, the UK, Italy and Slovenia","volume":"11","author":"Osterrieder","year":"2021","journal-title":"BMJ Open"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Kopa\u0144ska, M., Barna\u015b, E., B\u0142ajda, J., Kuduk, B., \u0141agowska, A., and Bana\u015b-Z\u0105bczyk, A. (2022). Effects of SARS-CoV-2 Inflammation on Selected Organ Systems of the Human Body. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23084178"},{"key":"ref_5","first-page":"199","article-title":"SARS-CoV-2 Effects on the Male Genitourinary System","volume":"10","author":"Connelly","year":"2022","journal-title":"Am. J. Clin. Exp. Urol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1161\/CIRCRESAHA.120.317015","article-title":"Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: Celebrating the 20th Anniversary of the Discovery of ACE2","volume":"126","author":"Gheblawi","year":"2020","journal-title":"Circ. Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"506","DOI":"10.5534\/wjmh.200134","article-title":"Male Fertility and the COVID-19 Pandemic: Systematic Review of the Literature","volume":"38","author":"Khalili","year":"2020","journal-title":"World J. Men\u2019s Health"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Hikmet, F., M\u00e9ar, L., Edvinsson, \u00c5., Micke, P., Uhl\u00e9n, M., and Lindskog, C. (2020). The protein expression profile of ACE2 in human tissues. Mol. Syst. Biol., 16.","DOI":"10.15252\/msb.20209610"},{"key":"ref_9","first-page":"1","article-title":"Interaction of SARS-CoV-2 with RAS\/ACE2 in the Female Reproductive System","volume":"16","author":"Zangeneh","year":"2022","journal-title":"J. Fam. Reprod. Health"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e053051","DOI":"10.1136\/bmjopen-2021-053051","article-title":"Impacts of COVID-19 and SARS-CoV-2 on male reproductive function: A systematic review and meta-analysis protocol","volume":"12","author":"Li","year":"2022","journal-title":"BMJ Open"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"677701","DOI":"10.3389\/fendo.2021.677701","article-title":"Effect of COVID-19 on Male Reproductive System\u2014A Systematic Review","volume":"12","author":"He","year":"2021","journal-title":"Front. Endocrinol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e14219","DOI":"10.1111\/and.14219","article-title":"Peyronie\u2019s disease in a patient after COVID-19 infection: A case report","volume":"53","author":"Rainer","year":"2021","journal-title":"Andrologia"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0140-6736(20)32667-2","article-title":"Male infertility","volume":"397","author":"Agarwal","year":"2021","journal-title":"Lancet"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"392","DOI":"10.4103\/1008-682X.179161","article-title":"Current updates on laboratory techniques for the diagnosis of male reproductive failure","volume":"18","author":"Sikka","year":"2016","journal-title":"Asian J. Androl."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"52","DOI":"10.5534\/wjmh.210022","article-title":"Standardized Laboratory Procedures, Quality Control and Quality Assurance Are Key Requirements for Accurate Semen Analysis in the Evaluation of Infertile Male","volume":"40","author":"Agarwal","year":"2022","journal-title":"World J. Men\u2019s Health"},{"key":"ref_16","first-page":"8","article-title":"Semen analysis is the cornerstone of investigation for male infertility","volume":"251","author":"Barratt","year":"2007","journal-title":"Practitioner"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"37533","DOI":"10.52965\/001c.37533","article-title":"Male Sexual Dysfunction","volume":"10","author":"Anderson","year":"2022","journal-title":"Health Psychol. Res."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/aja.2011.72","article-title":"Psychological and social aspects of infertility in men: An overview of the evidence and implications for psychologically informed clinical care and future research","volume":"14","author":"Fisher","year":"2012","journal-title":"Asian J. Androl."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0302-2838(03)00215-X","article-title":"Male erectile dysfunction and health-related quality of life","volume":"44","author":"Burgos","year":"2003","journal-title":"Eur. Urol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1007\/s10735-021-10003-3","article-title":"COVID-19 and male reproductive system: Pathogenic features and possible mechanisms","volume":"52","author":"Arab","year":"2021","journal-title":"J. Mol. Histol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/s41443-019-0161-8","article-title":"Trends in erectile dysfunction research from 2008 to 2018: A bibliometric analysis","volume":"32","author":"Hui","year":"2020","journal-title":"Int. J. Impot. Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"302","DOI":"10.5534\/wjmh.180114","article-title":"An In-Depth Bibliometric Analysis and Current Perspective on Male infertility Research","volume":"39","author":"Baskaran","year":"2021","journal-title":"World J. Men\u2019s Health"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1016\/j.jsxm.2018.08.004","article-title":"Bibliometric Analysis of Erectile Dysfunction Publications in Urology and Sexual Medicine Journals","volume":"15","author":"Rezaee","year":"2018","journal-title":"J. Sex. Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1111\/andr.12204","article-title":"Research trends and perspectives of male infertility: A bibliometric analysis of 20 years of scientific literature","volume":"4","author":"Zhang","year":"2016","journal-title":"Andrology"},{"key":"ref_25","first-page":"751","article-title":"The use of scientometric parameters for the evaluation of scientific contributions","volume":"23","year":"1999","journal-title":"Coll. Antropol."},{"key":"ref_26","unstructured":"de Oliveira, O.J., da Silva, F.F., Juliani, F., Barbosa, L.C.F.M., and Nunhes, T.V. (2019). Scientometrics Recent Advances, IntechOpen."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"e17703","DOI":"10.1016\/j.heliyon.2023.e17703","article-title":"COVID-19 pandemic sheds a new research spotlight on antiviral potential of essential oils\u2014A bibliometric study","volume":"9","author":"Ginting","year":"2023","journal-title":"Heliyon"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1135334","DOI":"10.3389\/fimmu.2023.1135334","article-title":"Current hotspot and study trend of innate immunity in COVID-19: A bibliometric analysis from 2020 to 2022","volume":"14","author":"Lai","year":"2023","journal-title":"Front. Immunol."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Yeung, A.W.K., Parvanov, E.D., Nawaz, F.A., Rayan, R.A., Kletecka-Pulker, M., Willschke, H., and Atanasov, A.G. (2022). COVID-19 Rapid Antigen Tests: Bibliometric Analysis of the Scientific Literature. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph191912493"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"3133","DOI":"10.1007\/s00330-023-09498-z","article-title":"COVID-19 imaging, where do we go from here? Bibliometric analysis of medical imaging in COVID-19","volume":"33","author":"Wen","year":"2023","journal-title":"Eur. Radiol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"4639","DOI":"10.1007\/s11192-021-03893-3","article-title":"Expert recommendations based on link prediction during the COVID-19 outbreak","volume":"126","author":"Wang","year":"2021","journal-title":"Scientometrics"},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Noruzi, A., Gholampour, B., Gholampour, S., Jafari, S., Farshid, R., Stanek, A., and Saboury, A.A. (2022). Current and Future Perspectives on the COVID-19 Vaccine: A Scientometric Review. J. Clin. Med., 11.","DOI":"10.3390\/jcm11030750"},{"key":"ref_33","unstructured":"Scopus (2023, July 30). Scopus Provides Unmatched Content and Data Quality, with Superior Search and Analytical Tools. Available online: https:\/\/www.elsevier.com\/solutions\/scopus\/how-scopus-works."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s11192-009-0146-3","article-title":"Software survey: VOSviewer, a computer program for bibliometric mapping","volume":"84","author":"Waltman","year":"2010","journal-title":"Scientometrics"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Tran, B.X., Ha, G.H., Nguyen, L.H., Vu, G.T., Hoang, M.T., Le, H.T., Latkin, C.A., Ho, C.S.H., and Ho, R.C.M. (2020). Studies of Novel Coronavirus Disease 19 (COVID-19) Pandemic: A Global Analysis of Literature. Int. J. Environ. Res. Public Health, 17.","DOI":"10.1101\/2020.05.05.20092635"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"e12","DOI":"10.1017\/dmp.2020.300","article-title":"Holistic Analysis of Coronavirus Literature: A Scientometric Study of the Global Publications Relevant to SARS-CoV-2 (COVID-19), MERS-CoV (MERS) and SARS-CoV (SARS)","volume":"15","author":"Topal","year":"2021","journal-title":"Disaster Med. Public Health Prep."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1022810","DOI":"10.3389\/fpubh.2022.1022810","article-title":"Bibliometric and visual analysis of cardiovascular diseases and COVID-19 research","volume":"10","author":"Wei","year":"2022","journal-title":"Front. Public Health"},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Hamidi, A., Khosravi, A., Hejazi, R., and Abtin, A. (2023). A scientometric approach to psychological research during the COVID-19 pandemic. Curr. Psychol., 1\u201310.","DOI":"10.1007\/s12144-023-04264-2"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"931575","DOI":"10.3389\/fpsyt.2022.931575","article-title":"Knowledge mapping analysis of mental health research on COVID-19","volume":"13","author":"Zhou","year":"2022","journal-title":"Front. Psychiatry"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.4103\/ijo.IJO_3284_20","article-title":"COVID-19 and ophthalmology: A scientometric analysis","volume":"69","author":"Kalra","year":"2021","journal-title":"Indian J. Ophthalmol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1530\/REP-20-0382","article-title":"COVID-19 and male reproductive function: A prospective, longitudinal cohort study","volume":"161","author":"Tartibian","year":"2021","journal-title":"Reproduction"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Wang, Z., and Xu, X. (2020). scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells. Cells, 9.","DOI":"10.20944\/preprints202002.0299.v1"},{"key":"ref_43","first-page":"1016","article-title":"Evidence for residual SARS-CoV-2 in corpus cavernosum of patients who recovered from COVID-19 infection","volume":"11","author":"Dursun","year":"2022","journal-title":"Andrology"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"466","DOI":"10.5534\/wjmh.210055","article-title":"COVID-19 Endothelial Dysfunction Can Cause Erectile Dysfunction: Histopathological, Immunohistochemical, and Ultrastructural Study of the Human Penis","volume":"39","author":"Kresch","year":"2021","journal-title":"World J. Men\u2019s Health"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/s15010-021-01724-4","article-title":"Dynamics of urinary and respiratory shedding of Severe acute respiratory syndrome virus 2 (SARS-CoV-2) RNA excludes urine as a relevant source of viral transmission","volume":"50","author":"Mumm","year":"2022","journal-title":"Infection"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Wong, D.W.L., Klinkhammer, B.M., Djudjaj, S., Villwock, S., Timm, M.C., Buhl, E.M., Wucherpfennig, S., Cacchi, C., Braunschweig, T., and Kn\u00fcchel-Clarke, R. (2021). Multisystemic Cellular Tropism of SARS-CoV-2 in Autopsies of COVID-19 Patients. Cells, 10.","DOI":"10.1101\/2021.06.03.21258241"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"e14145","DOI":"10.1111\/and.14145","article-title":"The presence of SARS-CoV-2 virus in semen samples of patients with COVID-19 pneumonia","volume":"53","author":"Saylam","year":"2021","journal-title":"Andrologia"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"e208292","DOI":"10.1001\/jamanetworkopen.2020.8292","article-title":"Clinical Characteristics and Results of Semen Tests Among Men with Coronavirus Disease 2019","volume":"3","author":"Li","year":"2020","journal-title":"JAMA Netw. Open"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"135","DOI":"10.4103\/aja2021103","article-title":"Assessment of SARS-CoV-2 RNA shedding in semen of 36 males with symptomatic, asymptomatic, and convalescent infection during the first and second wave of COVID-19 pandemic in Italy","volume":"24","author":"Pavone","year":"2022","journal-title":"Asian J. Androl."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1007\/s10815-021-02119-y","article-title":"A cohort study of men infected with COVID-19 for presence of SARS-CoV-2 virus in their semen","volume":"38","author":"Burke","year":"2021","journal-title":"J. Assist. Reprod. Genet."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.fertnstert.2020.05.028","article-title":"Assessment of SARS-CoV-2 in human semen-a cohort study","volume":"114","author":"Holtmann","year":"2020","journal-title":"Fertil. Steril."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1007\/s00011-021-01497-4","article-title":"COVID-19 disrupts the blood-testis barrier through the induction of inflammatory cytokines and disruption of junctional proteins","volume":"70","author":"Peirouvi","year":"2021","journal-title":"Inflamm. Res."},{"key":"ref_53","first-page":"e633","article-title":"PD36-01 Bioinformatic Analysis of RNA Sequencing Data of Testis from SARS-CoV-2 Infected Men Reveals Molecular Alteration of Germ Cell-Sertoli cell Junction Signaling Pathway","volume":"207","author":"Selvam","year":"2022","journal-title":"J. Urol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1007\/s10815-022-02540-x","article-title":"SARS-CoV-2 effects on sperm parameters: A meta-analysis study","volume":"39","author":"Xie","year":"2022","journal-title":"J. Assist. Reprod. Genet."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s43043-021-00089-w","article-title":"Semen parameters in men recovered from COVID-19: A systematic review and meta-analysis","volume":"26","author":"Tiwari","year":"2021","journal-title":"Middle East Fertil. Soc. J."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1007\/s40618-022-01801-x","article-title":"Andrological effects of SARS-Cov-2 infection: A systematic review and meta-analysis","volume":"45","author":"Corona","year":"2022","journal-title":"J. Endocrinol. Investig."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"e14776","DOI":"10.1016\/j.heliyon.2023.e14776","article-title":"A systematic review of the effect of COVID-19 on semen parameters","volume":"9","author":"Lan","year":"2023","journal-title":"Heliyon"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"335","DOI":"10.4103\/aja.aja_82_20","article-title":"Viral infections and implications for male reproductive health","volume":"23","author":"Teixeira","year":"2021","journal-title":"Asian J. Androl."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1071\/RD20130","article-title":"Hepatitis B virus surface protein induces oxidative stress by increasing peroxides and inhibiting antioxidant defences in human spermatozoa","volume":"32","author":"Cheng","year":"2020","journal-title":"Reprod. Fertil. Dev."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"782915","DOI":"10.3389\/frph.2022.782915","article-title":"Viral Infections and Male Infertility: A Comprehensive Review of the Role of Oxidative Stress","volume":"4","author":"Akhigbe","year":"2022","journal-title":"Front. Reprod. Health"},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"Panner Selvam, M.K., Baskaran, S., O\u2019Connell, S., Almajed, W., Hellstrom, W.J.G., and Sikka, S.C. (2022). Association between Seminal Oxidation-Reduction Potential and Sperm DNA Fragmentation-A Meta-Analysis. Antioxidants, 11.","DOI":"10.3390\/antiox11081563"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"T41","DOI":"10.1530\/JOE-15-0113","article-title":"60 Years of Neuroendocrinology: The hypothalamo-pituitary-gonadal axis","volume":"226","author":"Plant","year":"2015","journal-title":"J. Endocrinol."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Niederberger, C.S., Lipshultz, L.I., and Howards, S.S. (2009). Infertility in the Male, Cambridge University Press. [4th ed.].","DOI":"10.1017\/CBO9780511635656"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1007\/s40618-023-02055-x","article-title":"SARS-CoV-2 and male infertility: From short- to long-term impacts","volume":"46","author":"Dai","year":"2023","journal-title":"J. Endocrinol. Investig."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/cen.14537","article-title":"Male pituitary-gonadal axis dysfunction in post-acute COVID-19 syndrome-Prevalence and associated factors: A Mediterranean case series","volume":"96","author":"Merino","year":"2022","journal-title":"Clin. Endocrinol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"5977","DOI":"10.1038\/s41598-023-32211-5","article-title":"Long COVID and risk of erectile dysfunction in recovered patients from mild to moderate COVID-19","volume":"13","author":"Alarfaj","year":"2023","journal-title":"Sci. Rep."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1080\/13685538.2022.2104833","article-title":"Impact of COVID-19 on erectile function","volume":"25","author":"Adeyemi","year":"2022","journal-title":"Aging Male"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"e13912","DOI":"10.1111\/and.13912","article-title":"Investigation of SARS-CoV-2 in semen samples and the effects of COVID-19 on male sexual health by using semen analysis and serum male hormone profile: A cross-sectional, pilot study","volume":"53","author":"Temiz","year":"2021","journal-title":"Andrologia"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/andr.12942","article-title":"Effects of SARS-CoV-2 infection on male sex-related hormones in recovering patients","volume":"9","author":"Xu","year":"2021","journal-title":"Andrology"},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Harirugsakul, K., Wainipitapong, S., Phannajit, J., Paitoonpong, L., and Tantiwongse, K. (2022). Erectile dysfunction after COVID-19 recovery: A follow-up study. PLoS ONE, 17.","DOI":"10.1371\/journal.pone.0276429"},{"key":"ref_71","doi-asserted-by":"crossref","unstructured":"G\u00f6k, A., Altan, M., Do\u011fan, A.E., Eraslan, A., Uysal, F., \u00d6zt\u00fcrk, U., Saguner, A.M., and \u0130mamo\u011flu, M.A. (2023). Does Post-COVID-19 Erectile Dysfunction Improve over Time?. J. Clin. Med., 12.","DOI":"10.3390\/jcm12031241"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1038\/s41392-021-00508-4","article-title":"Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis, prognosis and drug target discovery","volume":"6","author":"Li","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"981471","DOI":"10.3389\/fgene.2022.981471","article-title":"COVID-19 inhibits spermatogenesis in the testes by inducing cellular senescence","volume":"13","author":"Wang","year":"2022","journal-title":"Front. Genet."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/s41423-020-00604-5","article-title":"Pathological and molecular examinations of postmortem testis biopsies reveal SARS-CoV-2 infection in the testis and spermatogenesis damage in COVID-19 patients","volume":"18","author":"Ma","year":"2021","journal-title":"Cell. Mol. Immunol."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"8601","DOI":"10.1021\/acsomega.1c06551","article-title":"Semen Proteomics of COVID-19 Convalescent Men Reveals Disruption of Key Biological Pathways Relevant to Male Reproductive Function","volume":"7","author":"Ghosh","year":"2022","journal-title":"ACS Omega"}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2039-7283\/13\/6\/118\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:12:05Z","timestamp":1760130725000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/13\/6\/118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,26]]},"references-count":75,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["clinpract13060118"],"URL":"https:\/\/doi.org\/10.3390\/clinpract13060118","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,26]]}}}