{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:37:26Z","timestamp":1793295446468,"version":"4.5.0"},"reference-count":83,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:00Z","timestamp":1716422400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Introduction: Osteosarcomas of the jaw (OSJs) are rare tumors with distinct characteristics from osteosarcomas affecting other bones. This study aims to analyze the clinical, pathological, and therapeutic characteristics of OSJs. Methods: A retrospective, descriptive cross-sectional study including patients diagnosed with OSJ registered at the \u201cLa Paz\u201d University Hospital, Madrid, was performed. Results: Data of eight patients with a diagnosis of OSJ were obtained during the study period of 22 years (2002\u20132024). The mean age of the patients was 41 years. The distribution was 1:1 between the maxilla and mandible. Painful inflammation was the most frequent clinical manifestation. Conventional osteoblastic osteosarcoma was the most predominant histological type. Survival rate at 5 years was 50%, which decreased to 25% at 10 years. Conclusions: OSJs differ from conventional osteosarcomas of long tubular bones. Surgery continues to be the mainstay of treatment. However, more studies are needed through which more standardized protocols can be proposed for adjuvant therapeutic management.<\/jats:p>","DOI":"10.3390\/clinpract14030077","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T09:58:47Z","timestamp":1716458327000},"page":"965-979","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Clinical and Pathological Features of Osteosarcomas of the Jaws: A Retrospective Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1710-2025","authenticated-orcid":false,"given":"Jesus","family":"Rodriguez-Molinero","sequence":"first","affiliation":[{"name":"Department of Nursery and Stomatology, Faculty of Health Sciences, Rey Juan Carlos University, 28922 Alcorc\u00f3n, Madrid, Spain"},{"name":"High-Performance Research, Development and Innovation Group in Dental Biomaterials of Rey Juan Carlos University, 28922 Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Juan","family":"Pozo-Kreilinger","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Universitario La Paz, 28046 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Antonio","family":"Ruiz-Roca","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Stomatology and Radiology, Faculty of Dentistry, University of Murcia, 30100 Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9468-6933","authenticated-orcid":false,"given":"Antonio Francisco","family":"Lopez-Sanchez","sequence":"additional","affiliation":[{"name":"Department of Nursery and Stomatology, Faculty of Health Sciences, Rey Juan Carlos University, 28922 Alcorc\u00f3n, Madrid, Spain"},{"name":"High-Performance Research, Development and Innovation Group in Dental Biomaterials of Rey Juan Carlos University, 28922 Alcorc\u00f3n, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6253-9800","authenticated-orcid":false,"given":"Jose Luis","family":"Cebrian-Carretero","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery Department, University Hospital La Paz, Paseo de la Castellana, 261, 28046 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s12105-021-01404-7","article-title":"Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours","volume":"16","author":"Vered","year":"2022","journal-title":"Head. 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