{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:39:58Z","timestamp":1787161198045,"version":"build-2736575974"},"reference-count":66,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:00:00Z","timestamp":1730160000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Introduction: Chronic obstructive pulmonary disease (COPD) has a severe impact on patients\u2019 health and can lead to multiple complications. Material and methods: We analyzed the co-occurrence of obstructive sleep apnea (OSA) in COPD patients hospitalized in the Pneumology Clinic of T\u00e2rgu Mure\u0219, Romania. Results: A total of 150 COPD patients were investigated by clinical examination, STOP-BANG and Epworth questionnaires, ventilatory polygraphy (PG), EKG, cardiac ultrasound, blood lipids, and sugar. Sixty-eight patients (45.3%) had OSA associated with COPD. A total of 61.7% were COPD gr. E, and 30.8% were gr. B. Frequently shown symptoms were snoring and nonrestorative sleep (100%), somnolence (73.5%), nocturnal awakenings (41.17%), morning headache (32.3%), and aggravated dyspnea. Types of OSA included obstructive (97.05%), central (2.5%), and associated obesity\u2013hypoventilation (39.7%). A total of 76.4% were recently diagnosed with OSA. Men predominated at 70.5%, 76.4% were smokers, and 61.7% had experienced alcohol abuse. A total of 25% were overweight, and 71% had obesity. A total of 13.2% belonged to the category of 38\u201350-year-olds, 55.8% were in the 51\u201365-year-old category, 17.6% were in the 66\u201370-year-old category, and roughly 13.2% were in the 71-year-old category. Overlap syndrome (OS) comorbidities and complications were frequently present: 41% experienced respiratory failure, 66.1% experienced blood hypertension, 58.8% experienced ischemic cardiac disease, 32.35% experienced diabetes mellitus, 50% experienced dyslipidemia, and 29.4% experienced cor pulmonale. Conclusions: OS conferred gravity or directly contributed to cardiovascular, respiratory, and metabolic complications. OS was associated with more severe COPD and obesity. The prevalence of smoking in OS patients was higher than the national\/European average.<\/jats:p>","DOI":"10.3390\/clinpract14060180","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T08:42:09Z","timestamp":1730191329000},"page":"2300-2312","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Insights into the Overlap of Chronic Obstructive Pulmonary Disease and Sleep Apnea: Experience from the Clinic of Pneumology, T\u00e2rgu Mure\u0219"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3558-2856","authenticated-orcid":false,"given":"Edith Simona","family":"Iano\u0219i","sequence":"first","affiliation":[{"name":"Pulmonology Discipline, University of Medicine Pharmacy, Sciences and Technology \u201cGeorge Emil Palade\u201d, 540139 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gall","family":"Zsuzs\u00e1nna","sequence":"additional","affiliation":[{"name":"Pediatry Discipline, University of Medicine Pharmacy, Sciences and Technology \u201cGeorge Emil Palade\u201d, 540139 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delia","family":"Rachi\u0219","sequence":"additional","affiliation":[{"name":"Clinic of Pulmonology, Clinical County Hospital, 540011 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0882-870X","authenticated-orcid":false,"given":"Drago\u0219","family":"Hu\u021banu","sequence":"additional","affiliation":[{"name":"Clinic of Pulmonology, Clinical County Hospital, 540011 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7785-0121","authenticated-orcid":false,"given":"Corina","family":"Budin","sequence":"additional","affiliation":[{"name":"Discipline of Pathophysiology, University of Medicine Pharmacy, Sciences and Technology \u201cGeorge Emil Palade\u201d, 540139 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paraschiva","family":"Postolache","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Pulmonology and Clinical Pharmacology, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Ia\u0219i, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Jimborean","sequence":"additional","affiliation":[{"name":"Pulmonology Discipline, University of Medicine Pharmacy, Sciences and Technology \u201cGeorge Emil Palade\u201d, 540139 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,29]]},"reference":[{"key":"ref_1","first-page":"e3453","article-title":"The Overlap Syndrome","volume":"10","author":"Singh","year":"2018","journal-title":"Cureus"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"259","DOI":"10.5664\/jcsm.4540","article-title":"Sleep disorders in chronic obstructive pulmonary disease: Etiology, impact, and management","volume":"11","author":"Budhiraja","year":"2015","journal-title":"J. Clin. 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