{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:53:03Z","timestamp":1760057583708,"version":"build-2065373602"},"reference-count":11,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Background: Jugular foramen syndrome (JFS) is a rare condition characterized by the compression or impairment of one or more terminal cranial nerves passing through the jugular foramen. Although malignancies are the primary cause of JFS. Methods: In this report, we present the first documented case of JFS caused by acute otitis media in an adult patient. Results: A 74-year-old woman presented with ear pain, hoarseness, dysphagia, dizziness, tinnitus, and hearing loss. A physical examination revealed a reddish-bulging tympanic membrane, left-sided hearing loss, right uvula deviation, and cranial nerve palsies affecting the ninth and tenth nerves. Imaging studies confirmed temporal bone inflammation, thrombosis of the sigmoid sinus extending into the internal jugular vein, and signs of thrombophlebitis of the jugular vein. The patient underwent a cortical mastoidectomy, sigmoid sinus decompression, and ventilation tube insertion, along with antibiotic, steroid, and anticoagulant therapy. Postoperatively, the patient\u2019s condition improved significantly. Conclusions: This case highlights the importance of considering complicated acute otitis media in the differential diagnosis of neurological abnormalities associated with JFS. A thorough evaluation of the patient\u2019s medical history and radiological imaging can assist in identifying the cause of the symptoms and guide appropriate surgical or conservative treatment. Further research is essential to gain more comprehensive insights into the pathophysiology and therapeutic interventions of JFS affecting the ears.<\/jats:p>","DOI":"10.3390\/clinpract15020034","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T10:25:57Z","timestamp":1739355957000},"page":"34","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case Study and Concise Literature Review: Adult Patient\u2019s Initial Manifestation of Complicated Acute Otitis Media Presenting as Jugular Foramen Syndrome"],"prefix":"10.3390","volume":"15","author":[{"given":"Sabri","family":"El-Saied","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head & Neck Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva 8410101, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oren","family":"Ziv","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head & Neck Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva 8410101, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aviad","family":"Sapir","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head & Neck Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva 8410101, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Yafit","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head & Neck Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva 8410101, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel M.","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head & Neck Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva 8410101, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1148\/radiographics.17.5.9308106","article-title":"Jugular foramen: A review of the anatomy, masses, and imaging characteristics","volume":"17","author":"Caldemeyer","year":"1997","journal-title":"Radiographics"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.10.008","article-title":"Vernet\u2019s syndrome associated with internal jugular vein thrombosis","volume":"28","author":"Lee","year":"2019","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s13365-018-0622-8","article-title":"Vernet syndrome resulting from varicella zoster virus infection-a very rare clinical presentation of a common viral infection","volume":"24","author":"Ferreira","year":"2018","journal-title":"J. Neurovirol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.clineuro.2004.08.006","article-title":"Jugular foramen syndrome caused by cholesteatoma","volume":"107","author":"Erol","year":"2005","journal-title":"Clin. Neurol. 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